Keppra and Irritability: What Users Say (Page 2)

• Jim...
• Taken for 5 to 10 years
• June 5, 2020

For Epilepsy "Been taking Keppra the whole time I've had epilepsy, which will be six years come next Christmas Eve. It will make you irritable the first few weeks, but that passes. I have one grand mal seizure once every three months. It's an alright drug if your epilepsy isn't a 'I have one every hour' type thing. (: Good luck!"

• Lyn...
• Taken for 1 to 2 years
• January 10, 2022

For Epilepsy "I took this medication during my pregnancy with my youngest son. I had almost 160 seizures during the pregnancy, plus I was a horrible person to be around due to the constant irritability. It was horrible. My son was delivered early to try to get me on a better medicine. My doctor suggested we try it again after the pregnancy, and it still didn't work. Horrible medicine!"

• Kri...
• Taken for 1 to 6 months
• May 12, 2025

"With each Keppra increase, I feel short-tempered, grumpy, tired, depressed, and definitely mad at the world, and an anger for myself as well for not being a better version of who I am. I think symptoms last like two or three weeks? My husband might beg to differ. I do need to try that vitamin B6."

• JRC...
• Taken for 1 to 2 years
• March 22, 2022

For Seizures "I started having seizures when I was 35. I’m now 72. I took Depakote for 35 years and was mostly successful in avoiding seizures, although I did have periodic breakthrough events without warning. About two years ago, I noticed I was getting frequent mouth infections. At this point, the neurologist weaned me off of Depakote over a six-week period and at the same time gradually increased the Keppra to 1500 mg per day. For the first three weeks on Keppra, I was tired and irritable, but that soon subsided. I took a precautionary EEG as well. So far, no seizures and no mouth infections."

• Emo...
• Taken for 1 to 6 months
• July 27, 2021

For Seizures "I was put on this medication after one seizure with no history of seizures of any kind. This medication is horrible!!! I plead with anyone who is taking this to ask for help, and if you have a loved one on it, know that they need your help. It causes severe confusion, nosebleeds, aggression, bad dreams, and irritability to name a few. My doctor was adamant that I needed it, but when I finally forgot to take it one day, I had a moment of clarity and looked up its side effects. I was floored that I was ever put on it. It was by far the worst experience I have ever had with a medication, especially one I didn’t need! I weaned myself off of it and worry about long-term effects from taking it for so long. I implore everyone to find something else if you suffer from seizures and ask a loved one to help you if you are having any of these horrific side effects. God bless you and good luck to you all! I give it a scale of 10 on effects for very negative side effects."

• pat...
• December 27, 2007

For Seizures "Keppra has been a difficult drug for me. I have had mood swings, mouth sores, no sleep, anger, and agitation."

• Win...
• Taken for 5 to 10 years
• January 16, 2016

For Seizures "Falling asleep most of the day and feeling zonked out. They do help, but there must be a kinder drug they could use on us. Also, I am grumpy, but then that could be me."

• Con...
• August 14, 2016

For Epilepsy "Anger, moodiness, hopelessness, irritability, trouble making cohesive thoughts, very serious suicidal urge. Same day after the first pill of 500 mg."