Keppra and Anger: What Users Say (Page 3)

• Kay...
• Taken for less than 1 month
• February 22, 2021

For Epilepsy "Worst medication I've ever been on. I am naturally a very calm, kind, and easygoing person. On Keppra, I suddenly became an aggressive and angry person. I did not realize this at first, but soon realized I was yelling at everyone and had explosive anger towards the smallest circumstances. I was on this for about a month. I have had amazing experiences on Lamictal (Generic: Lamotrigine)."

• Kay...
• Taken for less than 1 month
• February 22, 2021

For Epilepsy "Worst medication I've ever been on. I am naturally a very calm, kind, and easygoing person. On Keppra, I suddenly became an aggressive and angry person. I did not realize this at first, but soon realized I was yelling at everyone and had explosive anger towards the smallest circumstances. I was on this for about a month. I have had amazing experiences on Lamictal (Generic: Lamotrigine)."

• Mim...
• Taken for 6 months to 1 year
• February 20, 2021

For Seizures "I have been on Keppra for 10 months post-craniotomy to prevent seizures. Initially, I was taking 1000 mg per day and then was reduced to 500 mg per day. I had my neurologist lower the dose because I was becoming very aggressive. I was very mean and spoke with no filter. I have not had any seizures, it's more of a preventive measure. I hope I can get off this medication soon."

• Pet...
• Taken for less than 1 month
• July 8, 2022

For Seizures "It is for my son. He is more aggressive, and he will not eat. He had not had a seizure when he was put on Keppra. It was given to him instead of Tegretol. He has cerebral palsy and autism and cannot depend on himself. I tried to get in touch with the doctor several times regarding this issue and had no help. He has barely eaten in two weeks."

• Nic...
• Taken for 10 years or more
• November 8, 2021

For Epilepsy "This 'Med'/Keppra/Brivaracetam has always been Neuro's 1st choice since diagnosed in 2008 for 'Opiate induced Epilepsy' @30 (3000 mg). Not helped 'Absent' or 'Nocturnal Seizures'! Would take any 'Med' to avoid Sleep-Wandering, biting mouth to shreds & various injuries when awakened. Keppra = No thanks. The SIZE of the tabs are scary enough, increased anxiety, zombified 24/7, terrible lethargy, that KEPPRA RAGE & negative feelings as others have described. (Tegretol, Clobazam + Zebinix are helping more, tbh.) The gut feeling with others' experiences on this 'Med' confirms suspicions. Bless all.."

• Liv...
• Taken for 10 years or more
• August 26, 2021

For Epilepsy "I started Keppra XR in 2010, 2250 mg daily, and have been seizure-free to date. The first month was a bit rough as I felt disoriented and fatigued. I had a bit of a hiccup when my not-so-usual doctor switched me to immediate release generic. That was terrible! Suicide ideation, anger, and hostility. Life was really awful within 24 hours on that crap! I even got in trouble with the law by day two! Knowing that wasn’t me, I went back to my regular and much-loved doctor. Although not covered under my HMO, I needed my doctor and Keppra XR brand. I have no side effects other than I sometimes feel a little euphoric about an hour after my morning dose. Very satisfied with the results and living my best life."

• Liv...
• Taken for 10 years or more
• August 26, 2021

For Epilepsy "I started Keppra XR in 2010, 2250 mg daily, and have been seizure-free to date. The first month was a bit rough as I felt disoriented and fatigued. I had a bit of a hiccup when my not-so-usual doctor switched me to immediate release generic. That was terrible! Suicide ideation, anger, and hostility. Life was really awful within 24 hours on that crap! I even got in trouble with the law by day two! Knowing that wasn’t me, I went back to my regular and much-loved doctor. Although not covered under my HMO, I needed my doctor and Keppra XR brand. I have no side effects other than I sometimes feel a little euphoric about an hour after my morning dose. Very satisfied with the results and living my best life."

• Hur...
• Taken for 2 to 5 years
• October 8, 2021

For Seizures "Had first seizure at age 73. MRI didn't reveal anything. Dr. prescribed 750 mg twice a day. Questioned such a high dose, and he said some people take 3000 to 5000 mg a day. Have not had a seizure in 3 years, but side effects are horrible. Lightheadedness, weakness, anger, shortness of breath, loss of balance, drowsiness, ear infections. I am ready to reduce dosage and try to stop taking it altogether."

• Kri...
• Taken for 1 to 6 months
• May 12, 2025

"With each Keppra increase, I feel short-tempered, grumpy, tired, depressed, and definitely mad at the world, and an anger for myself as well for not being a better version of who I am. I think symptoms last like two or three weeks? My husband might beg to differ. I do need to try that vitamin B6."

• Emo...
• Taken for 1 to 6 months
• July 27, 2021

For Seizures "I was put on this medication after one seizure with no history of seizures of any kind. This medication is horrible!!! I plead with anyone who is taking this to ask for help, and if you have a loved one on it, know that they need your help. It causes severe confusion, nosebleeds, aggression, bad dreams, and irritability to name a few. My doctor was adamant that I needed it, but when I finally forgot to take it one day, I had a moment of clarity and looked up its side effects. I was floored that I was ever put on it. It was by far the worst experience I have ever had with a medication, especially one I didn’t need! I weaned myself off of it and worry about long-term effects from taking it for so long. I implore everyone to find something else if you suffer from seizures and ask a loved one to help you if you are having any of these horrific side effects. God bless you and good luck to you all! I give it a scale of 10 on effects for very negative side effects."

• Kit...
• August 26, 2013

For Seizures "Been on Keppra for 1 month. No seizures but very tired, depressed, and angry. 500mg morning, 500mg evening."

• pat...
• December 27, 2007

For Seizures "Keppra has been a difficult drug for me. I have had mood swings, mouth sores, no sleep, anger, and agitation."

• Kep...
• Taken for less than 1 month
• April 15, 2016

For Seizures "Within a week, suffered suicidal thoughts, psychosis, hallucinations, rages, and self-harming acts!"

• Nik...
• Taken for 1 to 2 years
• January 22, 2020

For Seizures "Keppra makes me sleepy, so I take it before bed. The only other side effect is nightmares, with talking, flailing, and swearing in my sleep. Lamictal and Topamax had worse side effects for me."

• JMG...
• Taken for 1 to 2 years
• December 25, 2022

For Epilepsy "This drug is awful. I have so much anger, and they got me on a high dose, but it’s not working. I also get tired easier."

• Con...
• August 14, 2016

For Epilepsy "Anger, moodiness, hopelessness, irritability, trouble making cohesive thoughts, very serious suicidal urge. Same day after the first pill of 500 mg."

• jam...
• March 13, 2023

For Epilepsy "Look, it does the job. I don't have seizures on it, but it also makes me mentally foggy, extremely sleepy, aggressive, depressed, and suicidal every now and then."

• Dha...
• Taken for 10 years or more
• June 2, 2016

For Epilepsy "This medication has been an on-and-off solution. It used to cause a lot of Keppra rage, but I am on another medication that is for seizures that also helps with my anger bouts."