Leuprolide and Weight Gain: What Users Say (Page 3)

• Mik...
• Taken for 1 to 2 years
• January 13, 2025

Leuprolide for Prostate Cancer "Overwhelming, suffocating hot flashes that cause instant full-body sweating. This has caused disruption to all aspects of each day (whether at work, at leisure time, or bedtime). This drug causes weight gain regardless of exercise intensity. It has completely stopped all sex drive or interest. It has caused genital shrinkage and, at times, discomfort. I have unusual fatigue and muscle atrophy. I have been getting the drug for a year and a half. I will not be able to tolerate any more of this drug. It has kept my testosterone level at near undetectable levels."

• Bru...
• Taken for 1 to 6 months
• December 26, 2024

Leuprolide for Prostate Cancer "I am taking this drug along with 10 mg of Prednisone, so some of my symptoms may be from either drug. I've been taking Lupron Depot for four months and the prednisone for eight months. Hot flashes, 15-20 per day. Lasting 3-4 minutes. Dizziness, but much better since I stopped taking Flomax. Weight gain, always hungry. Prednisone does this to me. Fainting, may be dehydrated at times. A bit of chest pain, but not serious."

• Mik...
• Taken for 1 to 2 years
• November 9, 2024

Leuprolide for Prostate Cancer "Given all the things that testosterone regulates in the male body, none of the side effects are unexpected. My blood work indicates that it’s working. The hot flashes, weight gain, fatigue, and mild vertigo (among other side effects) subsided in a few months, just in time for the next every-four-month injection."

• any...
• Taken for 2 to 5 years
• December 2, 2024

Leuprolide for Prostate Cancer "I have been on Lupron for 20 months now, and it reduced my PSA from .64 to undetectable. The side effects for me have been hot flashes a couple of times a day, loss of body hair, 20 pounds of weight gain, and complete loss of my sexual function and appetite. I will be going off Lupron when this shot wears off in a couple of months. I have been receiving the 6-month shot. I am 67 years old and have high-risk prostate cancer, have had my prostate removed, and went through 38 rounds of radiation. I feel I am doing as well as can be expected and do everything I like to do minus my libido. Good luck to all!"

• End...
• Taken for 1 to 6 months
• April 27, 2023

Leuprolide for Endometriosis "I am a 22-year-old Black woman who started taking this injection in February after undergoing diagnostic surgery for endometriosis. I don't know what stage of endo I'm in, but it has spread to my intestines, liver, ovaries, and bladder. When I was informed about the injection, I read about its effects, so I'm not surprised, but it doesn't make me feel any less miserable. I experience severe hot flashes day and night, weight gain, and a severely decreased libido. Fortunately, I haven't felt any joint pain yet, but I hope I never do. I'm scheduled for the second dose, but I'm on the fence about continuing due to my decreased libido and weight gain. This injection is affecting my self-esteem, but I can't handle being in pain for 13 days every month. Although I still had a period every month, my last one was the worst, with heavy bleeding, extreme bloating, and gastrointestinal pain. If you're informed about this injection, choose to use it wisely."

• Eag...
• Taken for 6 months to 1 year
• November 28, 2024

Leuprolide for Prostate Cancer "The 7 months of treatment I am on, along with 9 weeks of radiation, appears to be working well. My PSA (with stage 3 prostate cancer) went from 7+ to 0.05. That said, I am fighting brain fog, fatigue, slight weight gain, loss of sexual interest, nearly chronic dry cough, general itching, and joint and muscle pain. Looking forward to the product wearing off starting around 6 weeks from now. Strongly recommend resistance exercise, it helps a great deal!"

• Flo...
• July 22, 2014

Leuprolide for Prostate Cancer "Hot flashes and chills. Stomach became larger and weight gain. Hot flashes are very annoying. Fainted, and the doctor said it probably was due to dehydration."

• Sul...
• November 20, 2015

Leuprolide for Uterine Fibroids "This medicine has given me horrible headaches. Lost a lot of hair, gained weight, insomnia."

• Mul...
• September 24, 2017

For Prostate Cancer "Weight gain. Hot flashes. Shrinking testicles."