Lupron Depot-PED for Precocious Puberty User Reviews
Lupron Depot-PED has an average rating of 5.6 out of 10 from a total of 18 reviews for the treatment of Precocious Puberty. 39% of reviewers reported a positive experience, while 33% reported a negative experience.
Reviews for Lupron Depot-PED
- wor...
- July 26, 2015
"My daughter was prescribed Depo Lupron when she was about 6 years old. I would never recommend it to anyone. She gained a lot of weight, became obese, has a lot of stretch marks, has high cholesterol, high sugar levels, sleep apnea, and uses a CPAP machine to sleep. She fights with me to binge eat. I am so sad, I feel guilty for using this drug. I wish I would have let her get her period, she would have only struggled for a little bit with that, than with a lifetime of health issues. Who cares if they stay shorter? Short is beautiful too, and even big is beautiful, but this med gives health problems that did exist. I feel like I scarred her for life :("
- Anonymous
- April 10, 2010
"I was diagnosed with precocious puberty when I was 8 and started getting a Lupron shot once a month. It stopped all signs of puberty except the mood swings, which often worsened in the week before I got a shot. After 3 years, I was taken off the medicine and started puberty normally. I had continued to grow taller throughout that time and am now 5'1". My grandmother and cousin both had precocious puberty as well, and neither were treated. They both stopped growing around age nine and neither reached five feet."
Frequently asked questions
- Are Lupron Depot and Eligard the same drug?
- Will I get my period while on Lupron?
- What does Lupron do for IVF?
- Can you get pregnant on Lupron Depot?
- Anonymous
- May 21, 2008
"As a child, I encountered precocious puberty at the age of 8. My pediatrician then referred me to my endocrinologist. She suggested the vaccine to stop my puberty so I could grow, if not, I would end up being shorter than 5 feet. Now I'm 5'1 1/2, if it was not for this vaccine, I would not even have reached 5 feet. I am thankful for her and for my parents that put me through this four-year process of daily injections. It was a long ride, but it was worth it in the end."
- Anonymous
- August 15, 2008
"My 8-year-old daughter has been diagnosed with precocious puberty. While being proactive about the whole issue of stunted growth and early menses, we (my husband and I) were in the process of setting up an appointment to have her initial injection of the drug, Lupron Depot-PED, and guess what?...she started her first menstrual cycle. We still went ahead with the treatment as planned. We are three treatments into the whole plan, and things are going well, but there is a side effect that has lingered: hot flushes that are still waking her up during the night."
Are you taking this medicine?
Your review helps others make informed decisions.- Cia...
- June 26, 2009
"I have extreme mixed feelings about this drug. At the age of 5, I was diagnosed with precocious puberty. My endocrinologist suggested I start Lupron, and I did. It did exactly what it was supposed to do. I quit growing taller and stopped puberty-like symptoms. One problem: I did not grow taller, but I was still eating. I gained a lot of weight, but the doctors promised that once I quit the shots, everything would even out. I quit the shots after 7 years of treatment, and it did not 'even out.' The weight gain caused insulin resistance, which also played with my hormones and led to polycystic ovarian syndrome."
- PS7...
- Taken for 2 to 5 years
- January 8, 2016
"I was 7 or 8 when I started this treatment. My bone age at that time was of a 10-year-old. Now at 18, I have gained a lot of weight every year after stopping the medication. Although I don't seem like a person that weighs a lot, my BMI is on the higher end of normal. In addition to that, while on the treatment, I had a lot of acne. Apart from that, my periods are extremely irregular. I guess everyone handles medications and treatment differently. However, I would not recommend this drug at all. Firstly, it's extremely expensive if you do not have insurance. Secondly, people are supposed to grow by themselves. This drug has more negative side effects than positive ones."
More FAQ
- Nis...
- January 19, 2012
"I was diagnosed with CPP at the age of 7 and began the course of Lupron shots monthly and would go every six months for check-ups. I did get my period one time when I was 8 years old while still on the shot. I must have started treatment too late because I never reached my full adult height. Now, at the age of 22, I am right under 5 ft. (4'11). It caused a lot of weight gain as well."
- JLA...
- Taken for 5 to 10 years
- June 3, 2019
"My daughter was diagnosed with precocious puberty at the age of 2, however, she was born with enlarged breast buds, so she was probably born with it. However, it wasn't diagnosed until she was 2. She did Lupron injections every 28 days until the age of 9. Once she turned 9, one injection a month was not enough, so she had the Suprellin LA implant for 2 years until she was 11. Blood tests and X-rays always came back fine while on treatment. She did have a couple of years where she was a bit overweight, but that all went away. My daughter is now 18 and is suffering from joint pain, muscle weakness, lack of strength, moodiness, hand and wrist swelling, tiredness, numbness, tingling, painful periods, etc. The more I read, the more I think Lupron is the cause of her problems now. If I would have known then what I know now, I don't think we would have proceeded with the Lupron injections."
- cic...
- Taken for 2 to 5 years
- August 22, 2016
"I started Lupron when my daughter was 6 going on 7 years due to underarm odor, breast buds, pubic hair, and fear of her getting her period at an early age. The treatment did not reverse the budding of the breast or pubic, her pubic hair growth only increased. Neither am I certain if it is preventing her from getting her period sooner. I am certain that it stunted her growth, which is a common side effect. About 3 months ago, her doctor informed me that though he prescribed this treatment for her CPP and it is covered by the insurance, the insurance almost never covers the growth hormone he mentioned would be needed for her to regain the height she lost, he had never mentioned this before. Beware of issues like this."
- che...
- Taken for 5 to 10 years
- February 16, 2016
"My daughter was diagnosed at 6 years old with precocious puberty. Pubic hair, breast buds, underarm hair. We did Lupron injections until she was twelve. I am happy to say they seemed to work, she is now 5'8" and somewhat healthy. She has some issues. She has been on the line of pre-diabetic for years. She is somewhat overweight. She is about 208 lbs. She does have facial hair, and she has a thyroid issue, and now she has recently been diagnosed with lactose intolerance, extreme lactose intolerance. She only has 2 enzymes to break down lactose. She also has had to get on birth control to keep her period normal, and her periods are very painful. I have to tell myself that what we are dealing with now is minor compared to how she may have developed without it."
- Lee...
- February 11, 2020
"My daughter has just been diagnosed with precocious puberty. She is 3 years old with a bone age of 9 years old. Reading these comments has gotten me scared and overwhelmed. Has anyone found any other treatments?"
- Kav...
- Taken for 2 to 5 years
- January 5, 2017
"My daughter was diagnosed with precocious puberty at age 7. She takes the shots every 3 months and has been doing so for 2 years now. She had slight armpit hair, slight pubic hair, and breast buds. The shots did not stop puberty but slowed it down. I do recommend it. Her height has increased, and we hope to stop the shots when she turns 11."
- Gre...
- July 4, 2009
"My daughter was diagnosed with CPP at 2 years old. The pubic hair and breast development disappeared by changing to an all-organic diet even before starting the treatment. She still has mood swings, and her height has improved with the Lupron, but the doctor still can't give me a cause or hope of when we'll stop the vaccine."
- red...
- Taken for 5 to 10 years
- September 17, 2018
"One of the worst things to ever happen to me. I wish children weren't subjected to this. I had so many painful side effects after treatment. There was a point during my treatment where it was too painful to sit down or even walk. The injection site became a mass and swelled up to the size of a golf ball, was purple and green, and would bleed and release pus for weeks. I don't recommend this treatment to anyone."
- Ais...
- February 24, 2022
"My daughter was diagnosed with early puberty at the age of 5, and I was told this drug has no side effects. Every time she went for injections, she wasn’t moving properly afterward. The last incident was after her injection, she couldn’t walk. Every time she walked, she went right down. She has pain until today, and it hurts me to see her like this. Please, parents, don’t be fooled by these doctors. I wish I knew."
- Anonymous
- Taken for 10 years or more
- July 18, 2017
"My daughter is 11 years old, and she took Depo Lupron since she was 11 months old and stopped when she was 10 years old. My daughter is worse off more than before. I should have let nature take its course because my daughter is having some of the worst side effects ever. She forgets stuff and can't get out of bed. She is starting to get stiff bones, and her body locks up on her. She cramps so bad to the point she throws up or passes out. She can't play with her friends because she also developed back and neck problems as well. First, she used to take it every 28 days, and then it changed to every 3 months. I really think this is taking a toll on her. I'm afraid it might have messed up more than her body and mind. I'm afraid she might not be able to have children."
- Can...
- Taken for 5 to 10 years
- February 29, 2020
"I have a slim body type, small breasts, and only reached 5 feet. I took the Lupron injection for many years. I am now 22 and deal with irregular periods, chronic headaches, chronic neck and back pain, and weakness. I’ve experienced episodes of numbness, tingling, and confusion. It’s frustrating to not know whether these are long-term effects from the Lupron injection when other test results have come back negative. It feels like a dead end to receive some kind of relief and live a normal life."
- 507...
- Taken for 1 to 6 months
- July 12, 2021
"My daughter took 2 doses of Lupron Depot-PED, and she started with side effects such as headache, seizures, hand shakes, muscle pain, loss of equilibrium, and focal epilepsy symptoms. After 4 years without medication, the side effects are still active. She was hospitalized in intensive therapy due to the seizures for 10 days."
- Why...
- Taken for 1 to 2 years
- November 12, 2017
"My 9-year-old has been on this drug for a year and has put on 11 kg. I have just decided to stop the injections as I have read so much on long-term weight gain. Can anyone advise if they too have had this side effect? I’m now worried, even though I have stopped it, now how will she lose the weight as it just isn’t budging, though we have cut her calories, etc."
- cvh...
- February 23, 2009
"My daughter, than 3 1/2, now 6 1/2, started the Lupron 7.25 mg every 3 weeks. She did have a small side effect of hot flashes and eating ups and downs. This medication did take a while for her blood estrogen levels to even out, but the medication worked as it should have. We hope to stop the Lupron if all goes well. If not, we still have another 5 years or so of the shots."
- Dan...
- November 18, 2011
"My daughter is 7 years old now, but about 11 months ago, we (my wife and I) have noticed some abnormal symptoms in my daughter: hips growing, waist, armpits smells. We visited 1 endocrinologist, and she recommends us to use Lupron. I hope this works well with no side effects."
- Str...
- Taken for 2 to 5 years
- February 20, 2019
"My daughter started her treatment while still in elementary due to early development and strong underarm odors. The treatment went well through the whole treatment with regular blood testing and all. It wasn’t until she was done with the whole treatment did she start getting all these stretch marks. First under her buttocks and now at age 17 and at 5’6”, she has the stretch marks going all the way down her legs. Even her pediatrician was saying that wasn’t normal, but yet the dermatologist we’ve seen can't tell us anything. To date, we’ve seen 3, and she also had a biopsy done, and the results came back negative. The stretch marks are really bad looking all over her lower body, and I don’t know what to do. Thank God my daughter doesn’t let that stop her from wearing shorts or bathing suits."
- Mom...
- Taken for 1 to 2 years
- June 8, 2017
"Grecia-- I hope you'll find this message, even though it's been many years since you posted. My daughter also started Lupron PED at 2 years old. She's now 4. It has reversed her chest development and her growth is more on track now. But I'm just finding out about all these bad side affects. I haven't heard of anyone else starting the medicine so early like her, so I was wondering if your daughter ever had/has any bad side affects from using it. My daughter has the 11.25mg injection every 3 months. Our insurance just changed how the bill it so now it's going to be over $4k!!! Help!!!"
- wor...
- Taken for less than 1 month
- May 1, 2015
"My daughter is 7, will be 8 soon, and was diagnosed with CPP. I am on the fence about it, have read everything, but am still worried."
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- Drug class: gonadotropin releasing hormones
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"My 8-year-old daughter had signs of CPP: breast buds, armpit odor, and excessive height. After seeing the specialist and getting tests, the ultrasound said she developed 5 cysts on her ovaries. The hand x-ray said she had a bone age of 10. She started the monthly Lupron shot. She is now 10, and she has no cysts on her ovaries now. Yet her bone age shows 12. Her breast buds are completely gone. She never gained any excess weight. No night sweats. We plan to stop the shot right after her 11th birthday."