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Eligard and Weight Gain: What Users Say

Weight gain: mentioned by 6 users (15.0%)

Based on user experiences from 40 Eligard reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 37.5%
mood swings 22.5%
fatigue 17.5%
depression 15.0%
night sweats 15.0%
weight gain 15.0%
bone pain 12.5%
sexual dysfunction 12.5%
insomnia 10.0%
pain 10.0%

Reviews for Eligard

Commonly mentioned side effects
  • Pea...
  • Taken for 1 to 6 months
  • December 19, 2019

For Prostate Cancer "I am 68 years old. Had 6-month injection in August 2018. Doctor told me hot flashes and night sweats were the side effects. That I could handle. What I could not handle was the loss of cognitive functions, mood swings, loss of muscle mass, weight gain, thoughts of suicide, total erectile dysfunction, shrunken penis, and testicles. It has destroyed my life. I have still not recovered all of the cognitive functions I lost, cannot get rid of the extra weight, and to top it all off, my cancer was not to the point where I needed the hormone. Eligard may have saved lives, but to me, the treatment has destroyed my quality of life."

1 / 10
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  • Bar...
  • Taken for 1 to 6 months
  • May 2, 2020

For Prostate Cancer "Diagnosed with prostate cancer in April 2019, had a 6-month Lupron shot in May followed by 45 radiation treatments ending in early September. Went on vacation and able to do 2-3 mile hikes over rough terrain with only a little fatigue. Went in for a second shot in early November and they changed me to Eligard. They said it was virtually the same product. Within 2 weeks, I developed intense pain in my hips that has not gone away. Can hardly walk to the mailbox any longer due to the pain. Dealing with mood swings, minor depression, trouble sleeping, and have gained 30 pounds. Due to go back next Wednesday for another 6-month Eligard shot. Not going to happen."

1 / 10
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  • Rob...
  • February 25, 2021

For Prostate Cancer "Got the results back. In September 2020, I had a biopsy (thanks for the delay, COVID). It came back with a Gleason score of 9 and Grade 5! They tried to operate, but there was too much scar tissue. Next was the oncologist appointment, who said we need to do something now and that Eligard should stop it from growing. What they didn't say was that I would gain weight. The night sweats make you put covers on, take covers off all night, and I get up to pee up to 9 times a night. Feeling lethargic, dark thoughts and mood swings. An emotional wreck. Went to the GP who put me on antidepressant tablets, which have amplified my emotional state. Told the wife tonight that I'm not taking any more antidepressants, not doing Eligard, and not going to a planning day. I want to go out on my terms, feeling like myself, not juiced up on this rubbish. Facts are I could have some good years left without medication or go on feeling wound up and unintentionally pushing away those that care."

1 / 10
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Frequently asked questions

  • pof...
  • Taken for 2 to 5 years
  • October 25, 2020

For Prostate Cancer "I was diagnosed with prostate cancer in 2014 at 64 years old. My doctor said my best option for getting rid of the cancer was to have it removed. I went through the surgery in August 2014, but the cancer was not gone. I had 38 radiation treatments in 2015, and that kept my PSA low for two years. It went up to 1.0, and the doctor started giving me Eligard injections every 3 months beginning in 2018. I have severe depression with dark thoughts concerning my death eventually from this cancer. I also have weight gain and no sexual desires at all. I have no tolerance or patience, and it makes me very irritable. I must admit it works as it has kept my PSA below 1.0 for the last two years! I don't think I will take it much longer. My doctor is saying they are looking for a different treatment soon. I have no idea what that will be. It has taken all the joy of life out of me, and I am not interested in almost anything..."

5 / 10
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  • Ano...
  • Taken for 2 to 5 years
  • June 28, 2016

For Prostate Cancer "I am the wife of a man currently taking Eligard. I have to say it has worked to keep the prostate cancer from spreading, which is absolutely wonderful. However, it has caused a lot of other problems that have affected both of us. He has absolutely no sexual desire, he has developed what appears to be breasts, his penis has become inverted, and his testicles have decreased in size. His muscle mass has decreased as well, and the weight gain is mostly in his belly. I can only hope that he will regain his manhood if and when he is taken off this medication."

10 / 10
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  • Bik...
  • Taken for 6 months to 1 year
  • October 16, 2021

For Prostate Cancer "I was diagnosed with prostate cancer around Thanksgiving 2020 and given a one-month dose of Eligard about 2 months later. Then two more 6-month hormone shots of Eligard. I have also had SBRT and brachytherapy. So, while it is difficult to assign the side effects I am experiencing to the Eligard alone, I am affected by nearly all its known side effects. I have zero libido, 4 or 5 hot flashes per day, major loss of strength and energy, genital shrinkage, body hair loss, weight gain, frequent urination at night, some short-term memory loss, mood changes, apathy, and increased frequency of bowel movements. I have trouble carrying groceries up the stairs where I live now because of my loss of strength. I have continued to exercise, and I take calcium, vitamin D, and multivitamin supplements, but I am still getting progressively weaker. The good news is my PSA is around zero now, and if it doesn’t increase, I won’t have to get another Eligard injection when this last one wears off."

6 / 10
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