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Eligard and Fatigue: What Users Say

Fatigue: mentioned by 7 users (17.5%)

Based on user experiences from 40 Eligard reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 37.5%
mood swings 22.5%
fatigue 17.5%
depression 15.0%
night sweats 15.0%
weight gain 15.0%
bone pain 12.5%
sexual dysfunction 12.5%
insomnia 10.0%
pain 10.0%

Reviews for Eligard

Commonly mentioned side effects
  • Wal...
  • Taken for less than 1 month
  • January 9, 2020

For Prostate Cancer "Have had one month injection of Eligard and will not be taking another. Side effects including hot flashes, night sweats, fatigue, joint pains, mood swings, memory loss - I get the lot. Worst decision I ever made and hope the effects wear off ASAP. I would rather take my chances than be half the person I am now. Reading other comments where there seems to be no ending to the side effects gives me little hope for a reprieve. Oncologist gave me no impression I would be suffering like this. Just 'this is the standard treatment' - it does not cure the disease just supposedly slows it. Personally I would rather have less time and good quality of life."

3 / 10
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  • Bil...
  • May 21, 2020

For Prostate Cancer "Massive radical prostate surgery in 1997. Clear of the return of cancer until 2016, with a low PSA of 18 when discovered at my annual physical. No radiation, only Eligard every six months. Here it is 2020, and I am 86 years of age. Only side effects are an increase in weight (15 pounds), low energy level, and increased breast size. Never had hot flashes or sweating. COVID-19 has kept my wife and me housebound for the past 3 months, and we enjoy life in states of happiness, bliss, and joy. If one lives long enough, prostate cancer will eventually put you under. Too many symptoms to make a doctor's appointment. When I think it is cancer of the wrist, it's arthritis. When I think it's cancer of the lumbar region, it's vertebral discs. So why think you're going to live forever? Enjoy the love your wife, children, and friends offer and learn to appreciate how cancer progresses during the last phase of life. My wife has NEVER heard me complain."

10 / 10
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  • Pat...
  • July 24, 2021

For Prostate Cancer "I just got my 3rd shot of Eligard. Hard to say exact side effects, because I also have end-stage COPD. I haven't got a PSA yet, prior to Eligard, it was 7, then 17, then 24. Due to COVID, I put off seeing an oncologist for 7 months. I got both Moderna vax in March. I started radiation in April and finished on June 9. It seems each shot of Eligard is getting a bit worse. This last one hurt and burned longer, a minor issue. Hot flashes seem more frequent. I too go to the bathroom about 9 or 10 times a night, every 1 to 1.5 hours, but that was happening before Eligard. I am dizzy a lot, and I don't have much energy (I used to be quite active). I am 66 years old. My cancer rated as Stage 3, there were tumors on 8 of 12 biopsy samples. Surgery wasn't an option since scans showed it may have spread to lymph nodes. I will update this (if possible) with my PSA score this September. Good luck to everyone. I can't recommend Eligard or condemn it as of this writing."

5 / 10
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Frequently asked questions

  • Bik...
  • Taken for 6 months to 1 year
  • October 16, 2021

For Prostate Cancer "I was diagnosed with prostate cancer around Thanksgiving 2020 and given a one-month dose of Eligard about 2 months later. Then two more 6-month hormone shots of Eligard. I have also had SBRT and brachytherapy. So, while it is difficult to assign the side effects I am experiencing to the Eligard alone, I am affected by nearly all its known side effects. I have zero libido, 4 or 5 hot flashes per day, major loss of strength and energy, genital shrinkage, body hair loss, weight gain, frequent urination at night, some short-term memory loss, mood changes, apathy, and increased frequency of bowel movements. I have trouble carrying groceries up the stairs where I live now because of my loss of strength. I have continued to exercise, and I take calcium, vitamin D, and multivitamin supplements, but I am still getting progressively weaker. The good news is my PSA is around zero now, and if it doesn’t increase, I won’t have to get another Eligard injection when this last one wears off."

6 / 10
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  • geo...
  • Taken for 6 months to 1 year
  • October 1, 2024

For Prostate Cancer "Has helped reduce PSA from < 200 to .019 over 9 months of treatment. I've had 2 6mo shots. No problems with injections. Cannot differentiate which drug causes hot flashes, fatigue, and depression when receiving ADT. I'm receiving drugs and injections in my treatment. PSA number has steadily declined."

9 / 10
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  • Mar...
  • Taken for 6 months to 1 year
  • March 1, 2025

For Prostate Cancer "Have been getting 3-month injections of this for 4 cycles. Also had Docetaxel and Nubeqa. Apart from low energy, I have had no side effects from any of these drugs. I mean nothing. Low and lowering testosterone and PSA. I do not expect prostate cancer treatment to leave my sexual function unchanged. I am nearly 79 years of age. Eligard seems to be working and is causing me no ill issues."

10 / 10
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  • Cra...
  • Taken for less than 1 month
  • March 22, 2025

For Prostate Cancer "I'm 74, and I've been fighting prostate cancer for 8 years: radical prostatectomy, then heavy doses of radiation when the cancer returned the first time. Then another round of radiation when the cancer returned again. Last week, I started hormone therapy (Eligard), and I can barely get out of bed, I am so fatigued. Can anyone tell me if the fatigue situation improves with time? No way I can live with this for very long. Thanks."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.