Itraconazole and Headaches: What Users Say

• Bog...
• June 27, 2009

Itraconazole for Onychomycosis, Toenail "One small nail had 100% infection while 2-3 other toes (including big toes) were slightly affected. After one month it was clear. Sporanox was very effective. Healthy nail growth was apparent. But I stopped using the medicine because of the side effects, namely the sense of abnormal heart and mental function (not unlike the effects of pseudoephedrine), together with headaches and tiredness. I tried Lamisil for one month, and the improvement continued, but I suffered from nausea, tiredness, and occasional headaches. Now I have just started Diflucan."

• Bog...
• June 27, 2009

Itraconazole for Onychomycosis, Toenail "One small nail had 100% infection while 2-3 other toes (including big toes) were slightly affected. After one month it was clear. Sporanox was very effective. Healthy nail growth was apparent. But I stopped using the medicine because of the side effects, namely the sense of abnormal heart and mental function (not unlike the effects of pseudoephedrine), together with headaches and tiredness. I tried Lamisil for one month, and the improvement continued, but I suffered from nausea, tiredness, and occasional headaches. Now I have just started Diflucan."

• Anonymous
• Taken for less than 1 month
• July 23, 2020

Itraconazole for Onychomycosis, Toenail "I was prescribed Sporanox to take as a pulse therapy for a toenail fungal infection. Day 1 was okay. Woke up at night, thirsty and with a feeling of sand in my mouth. Day 2, small cough and breathing not 100%. Day 3, the worst nightmare of my life. Let me just say, I'm a healthy young person, running around 80 miles a month in addition to regular gym sessions. My resting HR is 45. Never in my life have I had even a headache. That day, I was extremely tired, coughing, the strongest headache in my life, constantly thirsty, literally thought the next stage was dying. It's day 5 (I stopped on day 3), and I still feel a headache and the lymph nodes behind my ears hurt very much for the second day in a row. I can't move my head too much without hurting. If you're thinking of taking this for a fungal infection in toes or fingers, consider a different therapy like laser options. It was too short of a therapy to see any effects, so I can't say if it would be effective, the side effects were too much."

• Bir...
• Taken for less than 1 month
• May 7, 2021

For Blastomycosis "I started a high dose. Had to stop as my liver and kidney levels went high. Then a couple of weeks later, started me again on 1 dose twice a day. Day 3, feeling sick, headaches, numbness, tingling in hands, tired, just not myself at all. I just sent another message to my doctor to see what to do. Also, I keep feeling like my heart is racing. I’m not liking it. That is, my body is not liking it."

• Ary...
• Taken for less than 1 month
• January 30, 2022

For Dermatophytosis "Started a course of 50 mg twice a day itraconazole, developed a mild to moderate headache every time I had a dose. Drinking a lot of water and having some food helped in reducing the headaches. However, a mild headache persisted throughout the day. I stopped taking the medicine after 5 days due to the headache, and now I am relying on a topical antifungal agent for a yeast infection. Did not have any other side effects, however, headache persisted throughout the day."