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Vistaril and Tiredness: What Users Say

Tiredness: mentioned by 13 users (5.6%)

Based on user experiences from 232 Vistaril reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 17.7%
anxiety 6.9%
tiredness 5.6%
panic attacks 3.4%
sleepy 3.4%
nausea 3.0%
depression 2.6%
dry mouth 2.6%
hallucinations 2.6%
headaches 2.6%

Reviews for Vistaril

Commonly mentioned side effects
  • Chr...
  • November 7, 2013

For Anxiety "I have been taking 25 mg of Vistaril once per day for about the past month. I take it at night. I have depression and anxiety pretty bad with the anxiety being the stronger of the two issues. I can't handle stress very well at all either. I am taking 40 mg of Prozac a day also. The Vistaril at first made me drowsy and lethargic. It took me about a week to adjust. Now I feel much better. I can sleep at night and feel decent when I wake up. It's not perfect but I am not getting any side effects and it's improved my life. I would recommend trying it but I would only take at night and do not drive after taking it until you get used to it."

8 / 10
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  • Lea...
  • Taken for less than 1 month
  • August 9, 2019

For Anxiety "My psychiatrist prescribed me Vistaril for anxiety after trying plenty of other drugs (Celexa, Lexapro, and Klonopin). I was also trying other drugs like Prozac, Ritalin, and Intuniv. The first couple of days it made me tired, but like with all antihistamines I've ever taken, it wears off incredibly quickly, and I build a tolerance quite quickly. I was specifically prescribed it for anxiety, but as far as that goes, I haven't noticed a difference whatsoever. My anxiety is pretty severe, and I've had it since I was really young. Although everyone is different, and this will work differently for everyone, I have been taking it for about three and a half weeks, and the only reason I still take it is because I get nausea and allergies. But I haven't noticed a dent in my anxiety with it. I've always needed something relatively strong for my anxiety."

6 / 10
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41 Report
  • soc...
  • Taken for less than 1 month
  • July 3, 2012

For Anxiety "Made me very tired and sedated, slowed heart beat and felt like I forgot to breathe. I took one 50 mg pill and it didn't kick in for 45 mins. I'd rather take a 1 mg Xanax for my panic attacks. Woke up in the morning extremely tired and foggy."

2 / 10
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71 Report

See also:

Frequently asked questions

  • Anonymous
  • February 16, 2012

For Anxiety "I love this medication. I've tried everything. This is something I only take as needed! If it makes you tired, you are taking too much... in my opinion. I thank my doctor! I hated all other medicines because I was too lethargic! I'm sure some folks need to do something stronger, as I have in the past, but this works for me! Thanks."

9 / 10
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73 Report
  • Anonymous
  • February 16, 2012

For Anxiety "I love this medication. I've tried everything. This is something I only take as needed! If it makes you tired, you are taking too much... in my opinion. I thank my doctor! I hated all other medicines because I was too lethargic! I'm sure some folks need to do something stronger, as I have in the past, but this works for me! Thanks."

9 / 10
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73 Report

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  • Pre...
  • October 3, 2016

For Anxiety "I was given Vistaril for anxiety, to be used 'as needed' for my panic/anxiety attacks, and for me, it did nothing but make me a little sleepy. I know most anti-panic drugs are sedatives, but those generally do more than make you tired. This one just made me tired and freaked out."

2 / 10
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52 Report
  • Ano...
  • December 11, 2016

For Anxiety "I was prescribed Vistaril 25 mg to help relieve tension and was told to take 2 pills, so 50 mg, if 1 25 mg pill didn't work. 50 mg didn't really help either. I felt no improvement in how I felt after taking it. I was told after 30 minutes of taking it I should've felt better, but it never happened. After 2 to 3 hours after taking it, I felt somewhat relaxed but was more tired than relaxed. Vistaril really didn't work out for me."

2 / 10
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40 Report

More FAQ

  • Try...
  • June 27, 2014

For Anxiety "This stuff was the pits. A half hour after I took my first pill, I was falling asleep. The tiredness became extremely intense. I had to cancel my plans for the evening and lay down. I was so crazy exhausted that I became anxious. I asked my prescriber for anti-anxiety medication. I have mild anxiety that makes me uncomfortable. This stuff just made me worse than a couch potato. Several hours later, I got intestinal cramps. Then I started throwing up."

1 / 10
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66 Report
  • KL ...
  • September 30, 2017

For Anxiety "I battle depression, anxiety, and severe insomnia, also allergies. Knocked me out cold, and my allergies seemed under control, anxiety a little better. Problem I couldn't shake being extremely tired the next day. All I could do was sleep, which doesn't help with depression."

3 / 10
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22 Report
  • Cra...
  • Taken for 1 to 6 months
  • November 23, 2017

For Anxiety "I have severe bipolar, extreme manic depressive, high anxiety, suicidal tendencies, and ADHD. I had never taken any medications until recently. I didn't believe anything was wrong. I recently admitted myself to a psychiatric hospital that specializes in chemical dependency and mental illness. I was prescribed Vistaril 50mg every 6 hours as needed. I like this medication a lot. It works quickly for me, and I've not experienced any issues with making me tired at all, and I only use it during the day. But I also have Seroquel 150mg, Neurontin two 100mg capsules three times a day, and Depakote 500mg, 1 in the morning and 2 at bedtime. Vistaril has been great for me."

7 / 10
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20 Report
  • Lin...
  • November 26, 2014

For Anxiety "Didn't help me with my anxiety at all. Just made me physically exhausted and unable to function during the day."

2 / 10
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84 Report
  • Anonymous
  • August 31, 2010

For Anxiety "I take Vistaril for anxiety, and it helps a lot. It does make me tired, but that's okay because I also have trouble sleeping due to the anxiety."

8 / 10
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62 Report
  • Anonymous
  • July 28, 2016

For Anxiety "It made me very sleepy. I didn't like feeling so tired. With other medications for anxiety, I had more sense of calmness rather than just feeling loopy and tired. I won't use it again."

2 / 10
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40 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.