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Hydrochlorothiazide User Reviews & Ratings (Page 3)

Brand names: Microzide, Esidrix, Ezide, Inzirqo, Hydro Par Carozide Diaqua Aquazide H

Hydrochlorothiazide has an average rating of 5.2 out of 10 from a total of 185 reviews on Drugs.com. 35% of reviewers reported a positive experience, while 38% reported a negative experience.

Reviews for Hydrochlorothiazide

Commonly mentioned side effects
  • Kim...
  • Taken for 1 to 6 months
  • November 1, 2015

For High Blood Pressure "I was diagnosed with HBP in late August and was prescribed HCTZ. For the past two months, I experienced nausea and dizziness almost every single day. On the 5th day of taking HCTZ, I got numbness on my scalp, which did go away. Still scary! I traveled with a huge water bottle everywhere I went for fear of becoming dizzy/lightheaded. Eating became a concern as my dizzy/lightheaded feelings were overwhelming after eating or if I waited too long to eat. I had an increase in migraine episodes. I barely got any before, and I had 4 episodes in the 2-month period. I already had cervical neck pain, but this medicine made it worse. I had to use a topical muscle rub and take Tylenol (one dose) almost every day. Needless to say, this medicine was not for me."

4 / 10
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  • Fra...
  • October 27, 2015

For High Blood Pressure "I take 10 mg Lisinopril, and it reduces my BP to the normal pre-hypertension range. My doctor decided to give me a water pill. Now, I have a history of drugs working the opposite on me. For instance, he put me on a beta blocker to help my BP and warned it would lower my normal heart rate. In 2 days, it increased my heart rate enough to put me in the hospital (where they kept giving it to me). It also caused me to have heart pains. I'm weaned from it but may have the heart pains for up to a year as a side effect. I've taken this water pill on 2 separate occasions, and it doesn't do anything but increase my lower BP number. I don't retain water, and my output does not increase. No more. Lisinopril, diet, and exercise are all I need to control my BP. No additional pills."

1 / 10
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  • Sta...
  • February 18, 2018

For High Blood Pressure "I've been on this medication for about 6 months for edema and high blood pressure. It helps with both issues, but I have horrible side effects: blurred vision, tiredness, sadness (never had this before), weight gain (even with exercise, I'm up almost 30 lbs in 6 months), back pain that feels like kidney pains, random headaches, hot flashes, increased sweating. I was on lisinopril prior to this, but that made my heart race. The only way to resolve is by healthy eating, exercise, and not taking this pill. I have an appointment next week with my doctor to take me off."

3 / 10
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Frequently asked questions

  • Rob...
  • Taken for less than 1 month
  • August 27, 2015

For High Blood Pressure "Prescribed HCTZ 25 mg a week ago today. This is my first experience with the drug. My BP was high and erratic, the drug is supposed to flush the excess salt from my system and help lower my BP. The first six days were fine, my BP was stabilizing and steadily decreasing. I didn't have a problem with excessive urination because I take the pill at night before bed. I also lost water weight (5 lbs. approx.). The adverse effects started today, day seven. I woke up feeling congested and dry in my right nostril and had a dry BM (which never happens). I am also lightheaded with mild nausea. This medication is not for me. I'll work more diligently on alternative ways to lower my BP."

4 / 10
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  • Anonymous
  • July 22, 2011

For High Blood Pressure "I have used hydrochlorothiazide 12.5 mg for about 2 months now. It has significantly lowered my blood pressure, but I have noticed the arches in my feet hurt, some leg pain, and dry mouth. I also feel I don't have the same ambition. I do not urinate any more frequently than usual. I do think it has affected my sex life though, lowering my sex drive. I take this along with a beta blocker called propranolol 20mg. I will have to get my potassium checked to see how it is doing though."

7 / 10
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  • mis...
  • Taken for 10 years or more
  • February 17, 2017

For High Blood Pressure "I took HCTZ for 12 years for blood pressure, as well as 2 meds for diabetes. Recently, I stopped taking HCTZ and started experiencing problems with hypoglycemia. I found that HCTZ was causing my blood sugar to rise, making it necessary for the second diabetes med. When I stopped taking glipizide, the hypoglycemia no longer occurred. HCTZ was a wonderful med for my blood pressure, it helped bring it down to normal levels, but as I found out 2 months ago, I was taking a second med for diabetes that I should not have had to take. If you are not diabetic, it might be a good med for you, but if you are, please be careful with this med."

6 / 10
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  • Gor...
  • July 4, 2016

For High Blood Pressure "I have HBP as a side effect of cyclosporine and Myfortic used as anti-rejection meds for a liver transplant. I was first on amlodipine, and after two years of numbness/severe chills/exhaustion/extreme susceptibility to cold (I am Canadian) and stage 2 kidney failure, I suspected it and discontinued it on my own. The named side effects cleared within six months, but the HBP also reappeared. Enter hydrochlorothiazide --- after two years my kidney function is normal - BP fully controlled @115/75 and absolutely no downside effects other than peeing a lot = No Big Deal! Great med for me."

10 / 10
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  • SPr...
  • Taken for 1 to 2 years
  • December 6, 2021

Hydrochlorothiazide for High Blood Pressure "In conjunction with Amlodipine, it worked well to lower my BP, which had been extremely high. However, after 1 year and a half, I began having dizzy spells. About a month after these started, I landed in the emergency room when my heart rate shot through the roof. While teaching, my heart suddenly began racing, and I thought I was about to blackout. I was rushed to the emergency room, where it was found that my potassium was so low, it was affecting my heart. I was immediately taken off hydrochlorothiazide and given potassium for a couple of days. Once off the drug, my arrhythmia attacks lessened and then completely stopped after about 2 months. If you are taking this drug, ensure your doctor is checking up on your potassium levels."

6 / 10
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  • mod...
  • May 2, 2016

For High Blood Pressure "I just started taking this medicine about a week ago. I'm 34 years old, healthy, active, and we believe my high blood pressure is attributed to genetics. I was adopted, so I am unsure whether or not I have a biological history of HBP. After a year of monitoring my BP, I finally decided that I needed to see the doc about it. He originally prescribed me Lisinopril, in which I became lightheaded and dizzy, so he switched me to HCTZ, starting off at 6.25 mg (dividing the 12.5 mg dosage). The day after I took my first dose, my BP had already gone down to normal levels. I was amazed. I really didn't experience anything else other than going to the bathroom more often, which isn't too inconvenient for me. But now I'm beginning to feel lazy."

7 / 10
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  • Boo...
  • Taken for less than 1 month
  • January 29, 2023

For High Blood Pressure "I started taking this medicine after having high blood pressure for 9 months. The first pill made me nauseous and dizzy. I was told that my body would get used to it. Seven days later, I have pain in my stomach and right lower side, severely nauseous, dizzy like being drunk, and I am a Type 2 diabetic. My blood sugar spiked 65%! I took my last pill on a Sunday, telehealth visit with the doctor on Monday, and was taken off this medication. It took me until Friday and 2 Imodium to get rid of the side effects."

1 / 10
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  • sup...
  • February 20, 2016

For High Blood Pressure "This med was added to enhance my present ACE inhibitor (Enalapril 20 mg/2x daily) to reduce my BP. Recently, I became extremely ill with a viral sinus infection, and ultimately my BP spiked because of fighting this wicked infection. The physician thought it may be prudent to lower the BP, so HCTZ was added to the regimen of treatment at 25 mg per day. I've been on it for 3 weeks. BP is normal, but it was normal before the infection on Enalapril. I am in good health, eat right, and exercise. I can't believe the side effects: extreme fatigue, nausea, gastric pains, muscle pains, weakness, anxiety, and on and on. I contacted the physician today, and she immediately removed me from the med. Be careful and be watchful if this med!!"

1 / 10
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  • KBa...
  • Taken for less than 1 month
  • October 1, 2019

For Edema "I took hydrochlorothiazide 12.5 mg for swollen ankles in my late 20s. I ended up in the ER with a heart rate of 130 and blood pressure of 170/120. I took it one other time just to see if it was the medication, and it was! Horrible chest palpitations and anxiety with them. No one can tell me why this medication had opposite effects. All I can think is possibly wasting too much potassium?"

1 / 10
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  • Kim...
  • July 6, 2009

For High Blood Pressure "I am 21 years old and I have high blood pressure. I was on hydrochlorothiazide for approximately 2 weeks when one night, about 3 hours after I took it, I had an allergic reaction. My hands, face, lips, and feet swelled up. I was itching and had difficulty breathing. My mom rushed me to the ER. If you have ANY of the previous symptoms, please go to the ER as soon as possible."

1 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • April 6, 2023

For High Blood Pressure "I was taking hydrochlorothiazide 25 mg, amlodipine 10 mg, and telmisartan 80 mg for 3 years without any noticeable side effects other than a slight decrease in serial urge. I recently did a blood work, and my potassium level was dangerously low at 1.3. I was immediately admitted to the hospital for 2 days, and I was taken off this hydrochlorothiazide. Please do blood tests regularly if you are on 25 mg of this drug."

4 / 10
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  • MeI...
  • Taken for 6 months to 1 year
  • March 27, 2023

For High Blood Pressure "I am a 62-year-old woman who had been taking Losartan for 7 years to manage my blood pressure, but it only brought it down to 134/90. I noticed fluid accumulation near my ankles, and my doctor switched me to HCTZ 25 mg in June 2022. Within weeks, my blood pressure decreased to a consistent 116/65, and I lost 8 pounds. However, in January 2023, my blood pressure started to increase to 134/92 and continued to climb until I ended up in the ER on March 23, 2023, with a blood pressure of 193/116, feeling chest pressure, dizziness, and a racing heart. The ambulance personnel and ER staff were unable to determine the cause, but they discovered that my potassium and magnesium levels were critically low and treated me accordingly. My regular doctor advised me to stop taking HCTZ immediately, and I have been feeling better for the past 5 days. However, I found HCTZ to be a powerful medication."

1 / 10
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  • Lac...
  • Taken for less than 1 month
  • August 9, 2016

For High Blood Pressure "I started taking this medicine 4 days ago. On day 3, the cramps started so badly that I couldn't do anything without my hands involuntarily becoming fists, sometimes both of them, to the point of my husband having to help me pry them apart. I also had dizziness, nausea, muscle pain, among others. None of which I had on the Benazapril. I talked to my doctor yesterday, and he switched me to something different. I'm hoping it helps!"

1 / 10
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  • Anonymous
  • October 9, 2011

For High Blood Pressure "I have taken hydrochlorothiazide for a number of years and felt that it helped lower my BP, but recently began feeling more fatigued, so my doctor raised my dose to 50 mg. I have had severe rashes and edema ever since. She is now running tests to see if I have developed lupus. I had just 3 months ago been diagnosed with fibromyalgia. I am in severe pain, have large rashes on both legs that itch ALL the time, and my feet and legs are so swollen that I can hardly walk, especially in the morning and late evening. She took me off HCTZ 5 days ago until the results of the tests come back. I am also taking 240 mg of Diltiazem HCl and 20 mg of Altace. I need help and answers fast. I have never been so sick."

1 / 10
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  • Mar...
  • October 26, 2015

For High Blood Pressure "I only took one-half a pill, had a terrible reaction, severe nerve pain in both forearms, weakness all over, went to the ER in the hospital for 3 days. Now I have loss of sensation in my skin on my left side and sciatic nerve pain, plus burning all the way down my leg and foot on my left side. I have had MRIs, pain blocks, CT scans, been to orthopedic, neurosurgeons, neurologists, etc., with no relief. I am in pain every day of my life thanks to this medicine. I could walk 3 miles 1 year ago, and now I cannot walk one block without extreme pain!"

1 / 10
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  • ban...
  • Taken for less than 1 month
  • December 17, 2017

For High Blood Pressure "I was prescribed this drug (25 mg) daily because I've had recurrent calcium kidney stones for 20 yrs., and BP was very high for me. I am 57, of normal weight, no other medical conditions other than moderately high cholesterol, which I take simvastatin to control. Within a few hours of taking the first dose, I felt like I was going to jump out of my skin. My heart was racing. Resting pulse rate was 115-120. My jumped up to 156/86. My bp before this used to be 120/78. But the day I went to dr., it was 145/83. My resting pulse 93. I think my problem may be more tachycardia and anxiety, and this med ramped it up. Took over 24 hrs. to get out of my system and had bloating in abdomen. Will never take it again...."

1 / 10
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  • Lum...
  • Taken for 1 to 6 months
  • January 23, 2016

For High Blood Pressure "Works with my lisinopril to lower my high blood pressure. Really bad dry mouth and throat the first week. Also, I pee all the time. My tummy has gotten smaller, and I fit into pants I could never wear."

8 / 10
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  • gor...
  • April 11, 2015

For High Blood Pressure "I hate this drug. My Dr. put me on 25 mg per day. It makes me lightheaded, run to the toilet every hour, constipated, and causes leg cramps. I don't know why he added a new drug instead of just upping the dose of Losartan."

2 / 10
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  • Kah...
  • January 15, 2010

For Edema "I had noticeable results within 24 hours. I had gained a lot of edema from Lyrica. This drug helped reverse that with little discomfort or side effects. I had an increased pulse at first and a little dizziness, but it went away quickly."

9 / 10
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  • Ema...
  • Taken for 1 to 6 months
  • March 24, 2016

For High Blood Pressure "This medication causes me to sweat profusely. It was so bad water was dripping off my hair and I was sweating all over my body. The sweating makes me miserable, and I believe dehydrated. When I tell the doctor, they just ignore me. It does not cause me to go to the bathroom more often, but I'm probably sweating it off. I was taking 25 mg. I also have type 2 diabetes. I saw diabetics shouldn't take this. I had taken it for years before I was sweating then too."

5 / 10
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  • Joe...
  • Taken for 2 to 5 years
  • September 3, 2024

For High Blood Pressure "I'm just here to say that although hydrochlorothiazide has worked to get rid of some of my fluid, it matters which manufacturer you get it from! I got switched to Heritage Pharma and Avet Pharma, which are the same company. I had a very strong urge to urinate and thought I actually had a UTI. I went back to my regular manufacturer and bam, that urge is gone. Don't let doctors make you think you're just being crazy. You know your body. Tell them what manufacturer you prefer. They can tell the pharmacy what you want. Each brand uses different ingredients that you may be more sensitive to."

7 / 10
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  • Mim...
  • Taken for less than 1 month
  • July 19, 2021

For High Blood Pressure "My doctor prescribed this medication for my high blood pressure, even though I have had a tendency for years to have low sodium. Five days after starting the med, I had a medical emergency due to critically low sodium and potassium and was hospitalized for 4 days to try and bring my levels back up. My doctor has since added this medication to my list of drugs I can’t take. The hospital doctor tried to convince me that my doctor did not make a mistake by prescribing this for me, but common sense tells me if a patient already has low sodium, don’t prescribe a drug that could potentially lower it even more. My doctor has said more than once that she has never had a patient react so severely to hydrochlorothiazide. I am living proof that it can and does happen."

1 / 10
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