Skip to main content

User Reviews for GlipiZIDE XL

GlipiZIDE XL has an average rating of 5.3 out of 10 from a total of 10 ratings on Drugs.com. 22% of reviewers reported a positive experience, while 33% reported a negative experience.

Condition Avg. Rating Reviews Compare
Diabetes, Type 2  
5.3
10 reviews 153 medications

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for GlipiZIDE XL

IpsoFatso · Taken for 1 to 6 months · February 20, 2019

For Diabetes, Type 2 "When I first started taking Glipizide-ER 5mg along with Trulicity- once a week, also metformin 1000mg in a.m. and 1000 mg at night. My blood sugars (BS) was dropping to 100-110. I also have insulin as needed on a sliding scale. I refilled my medicine, but maybe a different manufacturer, my BS are reading 195-255. I'm constipated, moody as heck, dizzy in the morning. I bounce off the walls like a pinball machine, not to mention that I have gained a lot of weight. I have not changed my diet, not much exercise because I feel like rubbish all the time. Tonight I threw the medicine in the trash. It's bad stuff with too many side effects."

2 / 10
Was this helpful?YesNo
SDee7 · September 8, 2015

For Diabetes, Type 2 "I started taking Glipizide ER initially with instructions to take it only if my blood glucose level was 180 or higher. I did not have to take it every day, but took it several times a week. Then I was started having a hard time controlling my daily glucose levels. My Hg A1c was higher, so the instructions were changed to 2 in the a.m. and 1 at night. I purchased the medication from a different source and it was a larger pill with now Glipazide XL instead of ER. I have experienced a number of side effects and feel worse with it than before I started taking it. The longer I have taken it the worse I feel. I feel drugged, want to sleep all the time, have a slight headache, more thirsty, constipation on occasion, dry eyes, and more. Yuck!"

3 / 10
Was this helpful?YesNo
mozayic · November 3, 2011

For Diabetes, Type 2 "I have taken Glipizide and Glipizide XL in conjunction with metformin for a number of years with no side effects. Anyone taking Glipizide (not XL) should be aware that blood sugar levels can plummet quickly and that dosage timing may need to be readjusted. With Glipizide XL, I have not experienced these fluctuations; however, the positive control appears to take effect much slower as this is a time-released form."

6 / 10
Was this helpful?YesNo
Loni Q · Taken for 5 to 10 years · March 4, 2013

For Diabetes, Type 2 "I have used Glipizide XL for about 6 years now as a secondary medicine. Glipizide helps to keep my blood sugar numbers within range and keeps me from having to use insulin as much as I would without it, which is a good thing. I haven't had any side effects from the glipizide at all. I'm very happy with this medication."

10 / 10
Was this helpful?YesNo
Baxter · Taken for 1 to 6 months · June 18, 2019

For Diabetes, Type 2 "My Dr. insisted I switch to Glipizide XLfrom glyburide. Well, this drug is NOT working at all for me even at an increased dosage. My fasting glucose readings are 100 to 150 points higher than when I was on glyburide. But try telling and convincing a Dr. they're wrong."

1 / 10
Was this helpful?YesNo
Wayo · Taken for 1 to 2 years · January 18, 2019

For Diabetes, Type 2 "Took this med for diabetes for almost two years. I found that it contributed or fungal infections in genital areas. This was not listed as a side affect. After I stopped taking it I no longer have this condition. It also caused sudden drops of my glucose levels."

6 / 10
Was this helpful?YesNo
sugarboy · Taken for 1 to 2 years · February 7, 2019

For Diabetes, Type 2 "I was originally on metformin 500mg one daily when my A1C went to 7%. This didn't help so my doctor added glipizide 5mg once daily to my regimen. Both my sugars and A1C did not come down. Then again I didn't change my eating habits or start exercising (but I am tall and thin, no weight problem here). After too much GI trouble I stopped taking the metformin and told my doctor I'd never take it again. So, he upped my glipizide to ER 10mg once daily. After changing my diet pretty dramatically (cut out refined sugars and carb intake) my sugars came down. However, now I'm having quite a few hypoglycemic attacks. Scary ones like with a BS of 31. And I live alone. So that's worrying me now. Maybe my adjusted diet has resulted in me not needing 10mg but maybe 5mg daily again? It's kind of scary though. I moved so I have to find new doctors and get new blood work so I'm hoping to hang in there and then learn possibly to not be so extreme in my eating and if the dose should go down."

5 / 10
Was this helpful?YesNo
rich · Taken for 2 to 5 years · September 3, 2022

For Diabetes, Type 2 "I have been taking Metformin (2×1000) and Glipizide 2.5 for two years and been able to keep my A1c to between 6.2 and 6.4. Trying to watch what I eat and get some exercise. No side effects. Working for me."

10 / 10
Was this helpful?YesNo
MarC · Taken for 5 to 10 years · August 23, 2021

For Diabetes, Type 2 "When I first was diagnosed with type 2 diabetes it frightened enough to watch everything I ate. I dieted hard, and lost 35 pounds in about 4 to 5 months. My doctor prescribed Glipizide to go along with the dieting. I brought my A1C from 7.6 to 6.8 in the first 6 months. That was about as low as I could get my A1C, so I guess the Glipizide worked but only marginally. The only side effect was I actually gained weight back when I stopped being as rigid with my diet."

5 / 10
Was this helpful?YesNo
Diabetes RN · Taken for 1 to 6 months · May 30, 2017

For Diabetes, Type 2 "Fabulous drug. My patients are doing so much better with Glipizide XL. Getting them to goal. Easy to take and no pre meal dosing."

Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.