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Glecaprevir / pibrentasvir for Hepatitis C User Reviews (Page 3)

Brand names: Mavyret

Glecaprevir / pibrentasvir has an average rating of 8.4 out of 10 from a total of 324 reviews for the treatment of Hepatitis C. 80% of reviewers reported a positive experience, while 8% reported a negative experience.

Reviews for Glecaprevir / pibrentasvir

  • Belie...
  • Taken for 1 to 6 months
  • May 16, 2019

Mavyret (glecaprevir / pibrentasvir) "Well, fabulous! Blood work done and hep-c gone after being on Mavyret! I go back in 3 months for follow up. Miracles are alive and well! And, Yes on the mental fog, I am still experiencing it. Like everything is sort of surreal. I feel you. Must say, this is a very strange feeling journey. Can't explain exactly what I mean but, very profound! God bless you all and I am praying for ALL of you! I love you..."

10 / 10
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  • Joy
  • Taken for 1 to 6 months
  • July 4, 2019

Mavyret (glecaprevir / pibrentasvir) "Started 8 week Mavyret treatment on June 3,2019. First 16 days were good. Then had flu like conditions for 10 days. Don't think it was related to treatment. Overall treatment has been good. I noticed I’m more tired and have a little less energy. I’ve lost weight but that is due to the flu or virus or whatever it was! I started with a viral load of about 6 million. Got my 4 week test done and I am now down to 15. A little disappointed it is still detected but sometimes that happens and I’m sure by the time I am done it will be gone. My advice is the same as everyone else. Lots of water. I take my pills at dinner time. The abbvie nurse who calls to check on me is wonderful. I will be glad when all of this is just a bad memory. Good luck to everyone."

10 / 10
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  • Jok
  • Taken for 1 to 6 months
  • August 20, 2019

Mavyret (glecaprevir / pibrentasvir) "I'm on week 7. Not sure what to say about side effects but most I've had are not listed. Heartburn within 45 min of taking every time, heavy weakness that feels like I'm being pulled down to the floor lasting 4-5 hours after taking. Dizziness and spaced out feeling. Some brain fog but seems to have gone away. I take Mavyret after noon meal and I'm basically worthless for about 5 hours, mornings are ok, no sleep problems. Main problem is heartburn and acid reflux, you can't take anything for the reflux so that makes it worse. Thanks to everyone for posting as this is the only place you can see all the real side effects."

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Frequently asked questions

  • Sam
  • Taken for 1 to 6 months
  • September 22, 2019

Mavyret (glecaprevir / pibrentasvir) "This med def has its ups and downs. Make sure you take it with food right before bed! It will create BAD insomnia otherwise. My main symptoms were being restless, sore, nauseous, headaches, clammy and occasional diarrhea. I was so exhausted the whole treatment. I did get a cold for about a week during it as well. I also went to the chiropractor during this treatment to help with back and body pains. I also saw a counsellor during this process as well. You have to keep up with the little things that keep you sane during this process because you’ll feel depressed and miserable. Just do what you can and don’t worry about perfection right now. It’s for a short time and soon you’ll be able to say you’re hep free like me!"

8 / 10
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  • DeeDee
  • Taken for 1 to 6 months
  • April 15, 2019

Mavyret (glecaprevir / pibrentasvir) "Two weeks of Mavyret treatment to go. Occasional loss of appetite, sometimes a slight headache, but not even needing an aspirin. No aches, brain fog, fatigue or nausea. Blood work at four weeks showed I hadn't cleared the virus completely, but my count went from over 1 million to 15. 15.....! Almost there! I take the pills around 7 pm with food, hasn't affected my sleep, energy level or concentration. Based on my experience 18 years ago with Interferon/Ribaviron, ( virus came back after 18 months of that brutal life -sapping treatment, during which it went undetectable) I was expecting the same side effects, if of a lesser intensity. I'm calling this the miracle we've been praying for."

10 / 10
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Are you taking this medicine?

  • Monica...
  • Taken for 1 to 6 months
  • December 6, 2017

Mavyret (glecaprevir / pibrentasvir) "I'm on my last six days of my eight week treatment. First round of labs is looking promising. Second set is next week . * Fingers crossed* And the side effects are very real and no I'm not just stating a headache, nausea and fatigue. About four weeks in I noticed a mental decline. Bouts of depression, anxiety and at times immense irritation, plus facial blemishes, thinning hair, weight gain and excessive sweating. Worth it, I hope considering if one stops treatment the likelihood of insurances authorizing another are very unlikely. I have always had adverse reactions to medicines (my luck), ultimately the potential benefits are worth it. Treatments Alleged Side effects suck vs. Hep C and its damage .. treatment was an easy win."

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  • Debra
  • Taken for less than 1 month
  • January 29, 2020

Mavyret (glecaprevir / pibrentasvir) "I just finished one month treatment on Mavyret and the side effects are definitely easing up. The effects at first were harsh. Flu like symptoms, fatigue, tummy ache, foggiest and prob the nausea was the worst of all for me. (I suffer from migraines so I’m more sensitive to nausea) but it’s lessening as I enter into the second month. I go for a first month checkup on Monday so I’m hoping things are looking good. Do the treatment your health is first priority. You will get through this and once your hep C free, this will be a distant memory. Good luck fellow patients!!!"

8 / 10
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More FAQ

  • Maree
  • Taken for less than 1 month
  • April 18, 2019

Mavyret (glecaprevir / pibrentasvir) "I am 44 years old (female) and have had hep c (geno 3a) for 19 years. I started experiencing fatigue in the last 3 years, but my liver is generally in good health considering. I contracted it off my partner, who had been living with the disease since the early 80’s. He had tried interferon twice, but unfortunately he died of liver cancer 3 years ago. I am sad that he never had the opportunity to try this wonderful drug. I am now on day 9 of my 8 week treatment. A few side effects... vivid dreams first 2 days; very tired; REALLY bad nausea. It’s only 8 weeks, so I just keep trucking. After watching my partner go through horrendous side effects from interferon, I count myself very lucky. I have a lot of confidence in this new drug. Good luck to all on the treatment."

8 / 10
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  • Krisg
  • Taken for 1 to 6 months
  • October 4, 2019

Mavyret (glecaprevir / pibrentasvir) "I just finished my 8-week treatment the day before yesterday. I had extreme fatigue, I was very depressed and thinking crazy stuff, had nightmares, was in a weird sleep the first few weeks like couldn't sleep but maybe I was asleep...I don't know just weird. Had diarrhea a few times and just very weak. I have 2 babies and could barely take care of them some days! It was a nightmare! I'm glad it's over! I haven't had blood work yet but will in a month. My doc told me to take 12 weeks but apparently got changed to 8 at end but said it was 8 whole time I'm pretty sure it was Medicaid not wanting to pay for more and my doc is lazy! I stopped day before yesterday and can't stop throwing up and having diarrhea today must be a bug I'm guessing. I was diagnosed in 2015 plus had some other liver issues besides hep.....wish everyone luck! It's not easy but can be done! I wish I would have known about this treatment a few years ago!"

3 / 10
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  • Spooks
  • February 22, 2020

Mavyret (glecaprevir / pibrentasvir) "Day 7: I feel that around 2 hours after I take the medication I get really nauseous and dizzy. I feel that it last about 2-3 hours. Once that goes away I feel fine besides the little heartburn I’ve been getting. I’ve been thinking about taking the medication at night with a snack before bed so that all the side effects happen then. I’m super grateful for the opportunity. I tried to get medication for this in 2012 and kept getting denied because of my insurance. So glad I’m able to take on this journey to freedom"

7 / 10
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  • Leelee
  • Taken for less than 1 month
  • October 18, 2019

Mavyret (glecaprevir / pibrentasvir) "Today is my first day on the treatment. I'm nervous about the side effects but I'm grateful that I have a chance to cure my hep c. Thanks everybody for your experience it helps prepare me just in case.."

4 / 10
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  • Careb...
  • September 23, 2019

Mavyret (glecaprevir / pibrentasvir) "Took Mavyret for the 8 weeks. Finished April 22nd and virus is undetected . Feel blessed or have gotten rid of it. So it’s been a full 5 months since I finished. The first 3 weeks taking Mavyret I had no side effects . But for the remaining 5 weeks. I felt like death. Never been that sick in my life ( extreme fatigue, brain fog, depression, chest pain, and right tightness, irritable muscle weakness itchy skin nightmares nauseous . Was in bed 20+ hrs a day. Good thing is I’m starting to feel better but very slow. Most days have nausea. Fatigue( I’m bed 15 hrs a day) bone and joint pain, irritable. But everyday gets a tiny bit better. This had been challenging but I’m cured. * also has anyone else had recurring candida infection after or during Mavyret treatment"

10 / 10
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  • Kellb...
  • Taken for 1 to 6 months
  • January 11, 2020

Mavyret (glecaprevir / pibrentasvir) "I did the 8 week treatment after getting hep c in 2004. My levels were pretty low when I started the medication and cat scan shows stage 2 liver fibrosis. I had zero negative side effects. On day 3, I did begin to get a lot of energy, almost to the point of feeling nervous, but I was getting so much accomplished because I had energy to do things. I had my levels checked after I finished and they were below 12 which means it is normal. I go for my 3m in a few weeks and we will see if it stayed negative."

10 / 10
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  • Rissa
  • Taken for 1 to 6 months
  • March 3, 2020

Mavyret (glecaprevir / pibrentasvir) "I completed the 8 week course of Mavyret a few weeks ago. The beginning of taking it I had a real bad headache for about a week and trouble getting to sleep but after the headache went away I had no other side effects. Waiting for the results of the blood testing to see if it worked but I am hopeful. Will update results upon . I was very nervous to do this treatment but it went pretty easily minus a the headache."

9 / 10
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  • Marie
  • Taken for less than 1 month
  • August 26, 2020

Mavyret (glecaprevir / pibrentasvir) "I'm on my third week of Mavyret at my 2 week mark they did lab work to make sure the medicine was doing it's job & not making it worse, almost a month ago my liver function were at a 160 & 116. On my third week and my lab work came back and my liver function is 27 and 16 "

10 / 10
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  • Drea
  • Taken for less than 1 month
  • March 17, 2019

Mavyret (glecaprevir / pibrentasvir) "I'm on my second day of Mavyret. Haven't had any side effects yet, so that's a good sign. Have waited 20 years for this and I'm so happy it finally came on March 15, 2019 at 12:45 pm. I'm doing the 8 week treatment, and it comes in 4 small boxes( for a month with 7 individual smaller boxes (in slots)with the 3 pills in each one, one box for each week. You take 3 pills at once and my doctor told me to eat at least 30 min before you take it and drink lots of water the whole time you're on the treatment, this way it would help with the side effects. So for 2 days I've been drinking lots of water and I eat a healthy meal 30 min before taking my pills. I decided to eat at 5 pm, and take my pills at 5:45 PM. Gave myself 15 mins to eat and 30 mins for my food to settle a little bit. And since my doc said it could cause fatigue, I chose to take it after dinner just incase I get tired. This way my whole day isn't wasted by being even more tired then usual."

10 / 10
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  • Suppa...
  • Taken for 1 to 6 months
  • September 15, 2018

Mavyret (glecaprevir / pibrentasvir) "I’m CURED. Genotype 3. I did 16 weeks because I had prior unsuccessful treatment with interferon and ribavirin. Just did a blood test after 3 months the end of the treatment and virus is undetectable which means I’m cured. I feel thankful and amazing. Thanks for Mavyret. Let’s erradicate this disease."

10 / 10
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  • Their...
  • Taken for less than 1 month
  • December 26, 2019

Mavyret (glecaprevir / pibrentasvir) "Day 4 on mavyret. I am taking it at 10 pm before I go to sleep. I have had slight nausea during the day but have not thrown up. I don't feel tired but my body feels weak. I have extreme thirst. I drink 3 cups of water at a time and still can't quench my thirst. Other than that not much to report. Got a ways to go but overall it's not to bad."

9 / 10
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  • Hol
  • Taken for 1 to 6 months
  • May 27, 2019

Mavyret (glecaprevir / pibrentasvir) "Had hep C over 30 years, took Mavyret 8 weeks, finished a year ago end of May. I have tested 3 times since, no active virus, normal liver panels, still get pain in liver area occasionally, do have fatty liver, working on lowering carb intake. Side effects were not great, anxiety, sleep problems, depressed, first and last week were unbearable, stomach felt like hole burning in it. The best time to take meds were with a huge meal around 7pm..then go to bed. I did notice I have raised tiny bumps scattered all over my body ,were never there before, but at least I have more energy and can do family outings now..."

8 / 10
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  • MMC
  • Taken for 1 to 6 months
  • September 15, 2018

Mavyret (glecaprevir / pibrentasvir) "My 63 year old brother died today. He took Mavyret for his Hep C. Cancer was not detected. Under a year after taking this medication, he died of cholangiocarcinoma (Bile duct cancer). We don’t know yet of the connection but he did not have it before. He was in healthy shape. He was diagnosed on August 6, 2018 and died today, September 15, 2018. We are heartsick."

1 / 10
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  • LAMike
  • Taken for 1 to 6 months
  • August 26, 2018

Mavyret (glecaprevir / pibrentasvir) "I am 4 1/2 weeks into treatment out of 8 weeks. Week 4, I notice my cognitive thinking is improving. And my depression and anxiety is a 2 out of 10 today. Before treatment it was a constant 5-8. Still have hep C effects. Like fatigue, soreness in my knees and ankles is still there. But less. My energy level is almost 50% and soreness in my joints is subsiding. Plus I have very few side effects from the treatment. Which are minimal not even worth mentioning."

10 / 10
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  • Kt57
  • Taken for 1 to 6 months
  • April 2, 2024

Mavyret (glecaprevir / pibrentasvir) "I've been on Mavyret for 6 weeks now & the only thing I have noticed is an upset stomach in the mornings & that I am constantly hot. It can be 63 out & I’m going to be sweating! I'm looking forward to my follow-up in 2 weeks for testing & hope to be negative! Don't let small side effects stop you from living the longest life possible!"

9 / 10
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  • Kelli...
  • Taken for less than 1 month
  • August 16, 2019

Mavyret (glecaprevir / pibrentasvir) "I am on day 9 and have no side effects. Not one headache, not tired, not foggy. So far so good. Hoping it won't develop as I go on. The only thing I have noticed is a lot of energy. Almost to the point of a nervous energy. On occasion a bit shaky inside. I am not complaining. It is better than the 0 energy I had before I started. Will report more as I go."

10 / 10
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  • Kaoti...
  • October 5, 2019

Mavyret (glecaprevir / pibrentasvir) "So I just took the 1st days pills for week 3. The very 1st 3 days were the worst so far with the most side effects. However those we're mild compared to the complications the hep c causes on it's own. I do have brain fog daily within 2 hours of taking my pills with that peaking by late afternoon. Sometimes if I don't eat enough through the day I get a mild ill tummy. Easy fix. I suffer from daily & weekly headaches & migraines. But I've noticed twice I've had new style migraine which I'm assuming was from medication. Easily fixed with some Excedrin & extra fluids. I'll come back to comment again prob after week 4 blood work when I'll have real results of if I'm responding for you. I would like to add this; I went in this knowing despite being told no side effects. I very well could be sick all 8 weeks & sicker then I've ever been. I was willing to do that just to finally be well. So if that's your fear keeping you from getting treated. Just do it. Weeks compared to decades sick & death are worth it."

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  • Grate...
  • Taken for 1 to 6 months
  • March 26, 2019

Mavyret (glecaprevir / pibrentasvir) "I was diagnosed in 2012 was advised not to seek treatment as new meds were coming out. Took me until now, 2019, to put enough clean time together to be approved for meds. I’m on my last two days of an eight week treatment. Blood works done four days ago shows I have cleared the Hep C!! Have experienced extreme fatigue and light headaches. First week felt flu-ish. Wondering how long after stopping did other people notice their fatigue end? My doc swears that it’s immediate, and that I will also see how tired the hep C was making me prior to treatment. So grateful for this medication; also grateful it was covered by insurance."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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