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Famotidine and Anxiety: What Users Say (Page 2)

Brand names: Pepcid, Pepcid AC, Zantac 360, Heartburn Relief, Pepcid AC Maximum Strength, Pepcid Oral Suspension, Acid Reducer-Famotidine, Acid Reducer Maximum Strength, Heartburn Relief Maximum Strength, Pepcid AC Chewable Tablets, Pepcid AC Maximum Strength Tablets, Acid Reducer Original Strength, Acid Controller Original Strength, Acid Controller Maximum Strength Acid Control …show all brand names

Reviews for Famotidine

Commonly mentioned side effects
  • Alf...
  • Taken for less than 1 month
  • January 6, 2020

For Stomach Ulcer "Having stomach pains resulting from oral antibiotic treatment for diverticulitis. Famotidine worked great - pain went away overnight. Had huge anxiety attack on second day (never had one before). Was on famotidine 20 mg twice/day. Decided to stop it."

8 / 10
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33 Report
  • Lad...
  • Taken for less than 1 month
  • January 11, 2022

For GERD "After about a week on famotidine, I didn't really notice where it was helping me with the heartburn that I had. I had to supplement the famotidine with over-the-counter antacids like Pepto-Bismol or a bicarbonate tablet. But I would say about five or six days into taking famotidine, I started to have palpitations and feelings of discomfort in my chest, and then with that came feelings of anxiety and other symptoms like my muscles hurting, sides, and my back hurting, feeling like my kidneys are hurting, just all. I started to have slight headaches for no reason, and I drink a lot of water per day. I do not recommend H2 blockers and PPIs because just tweaking your diet can actually help your digestive tract a lot better than swallowing this garbage that actually damages your stomach and your intestines in the long run. I would not recommend famotidine to take longer than a week, and I have noticed in some of these reviews people have been on this medicine for a year-wow, I can't do it!"

2 / 10
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22 Report
  • cou...
  • Taken for less than 1 month
  • September 15, 2022

For GERD "I took 10 mg of famotidine twice a day for severe GERD. I had stomach and chest pressure, shortness of breath, anxiety, burning, belching, nausea, and throbbing. It was enough for me to end up in the ER. The famotidine helped my symptoms after the first dose, but by the second day, I felt like I was losing my mind. I felt like my brain wasn't mine, I felt weird and detached. I was having panic attacks, I felt agitated, shortness of breath, and like I couldn't really speak. I felt really scared of my own mind. Turns out it's some of the 'rare' side effects. Super helpful for my symptoms, but not worth these horrendous side effects."

2 / 10
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16 Report

Frequently asked questions

  • Kmr...
  • Taken for less than 1 month
  • May 4, 2022

For Indigestion "Got prescribed this for basic indigestion, was told to take 2 a day for 2 weeks. Only managed to take it for a week until I started having debilitating panic attacks, full-body muscle spasms constantly. I feel like I’m stuck in a state of panic, and it won’t go away. It’s been about a week and a half since I last took it, and the symptoms haven’t really slowed down. My stomach is fine now, but this constant anxiety is unbelievable. Would not recommend in any capacity."

1 / 10
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17 Report
  • Fam...
  • Taken for less than 1 month
  • March 15, 2022

For Peptic Ulcer "The side effects are worse than the pain. I was prescribed 20 mg famotidine twice a day. I experienced extreme anxiety, sleeplessness, increased heart rate, and sweats to the point of almost fainting within 2 days. I stopped taking it. It is just not worth adding all those symptoms on top of stomach pain. I can't believe with all the negative side effects it's on the market. I've never experienced such terrible side effects in my life."

1 / 10
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16 Report

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  • Car...
  • Taken for less than 1 month
  • October 6, 2021

For GERD "Took it for four days for acid reflux, which it fixed. Suddenly felt high anxiety, palpitations, and insomnia on the fourth day. I stopped taking it, and my normal sleep schedule returned at first. Now I'm experiencing insomnia and palpitations the day after I exercise. It's been almost two weeks since I stopped. I'm hoping this goes away soon. It's misery, and I'll never take this drug again."

1 / 10
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18 Report
  • Lau...
  • March 19, 2023

For GERD "I was prescribed famotidine 20 by my ENT doctor at bedtime. Went in with sinus issues, and he went down my nose/throat and noticed severe acid reflux, which is odd because I rarely get heartburn. Been taking it for a week and noticing odd things. I will discontinue it tonight to see if the side effects go away. I started burping a lot and would wake up nauseous. Breathing sometimes is off, and felt like I have a chest gas bubble that won’t come out, and I have been taking Gas-X. The chest discomfort made my anxiety worse some days. At first, I was happy with this medication because it helped me sleep and stopped my dry cough at night, but a lot of these issues started after taking it. When I burp, it does relieve the pressure, but then comes back later on, and today started randomly feeling leg pain. I’m hoping after I stop, the issues will subside. Otherwise, it’s another issue."

2 / 10
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6 Report
  • NO ...
  • Taken for less than 1 month
  • January 28, 2023

For GERD "I was prescribed famotidine for my stomach issues. I took this medication for a couple of weeks, and it seemed to help stomach issues, however, I had severe twitching and cramps in my right leg for three days, so I stopped taking famotidine. Recently, my stomach started to play up, went to the doctor, and was prescribed another H2 receptor medication, but it was not in stock, and I had to take famotidine. I took 40 mg at night for 3 nights and was fine, however, on the third night, I started to feel high levels of anxiety, had a strange feeling in my head, and had insomnia. I won't be continuing to take this medication anymore."

2 / 10
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6 Report
  • Ale...
  • Taken for less than 1 month
  • August 6, 2021

For GERD "I was prescribed famotidine to help with my GERD and excess acid. The first day was fine, but the next day was horrible. I had anxiety, cough, muscle spasms in my legs and foot, and my blood pressure went through the roof. It shot up to 188/108! I stopped taking it and will go back to Protonix until I can see my GI doc. Really disappointing because it did help my GERD."

2 / 10
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8 Report
  • Its...
  • Taken for 1 to 6 months
  • October 20, 2021

For Peptic Ulcer "Started taking this for a month, 40 mg twice a day for gastritis. Noticed a lot of anxiety after taking it. Plus hallucinations, dizziness, feeling tired. Plus shoulder joints and back hurts. Had heart palpitations. Having hot flashes also. I've cut it down to when I need it. I pretty much feel back to normal again. Med works, just not worth the side effects. PPIs mess with your absorption of food. You don't get all your nutrients. I think it's messed up my gut. Diarrhea more than usual. Wish I never started it."

4 / 10
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7 Report
  • Ano...
  • November 14, 2020

For Indigestion "Famotidine is not the most effective thing I've taken for heartburn (Prevacid is awesome but gives me headaches), but it's helpful for cases where Rolaids and Pepto-Bismol don't give me relief. I feel just a bit off when I take it, but I'd rather feel out of it for a few hours instead of suffering through wicked heartburn."

7 / 10
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10 Report
  • Eli...
  • Taken for 1 to 6 months
  • May 17, 2023

For GERD "Controls the acid in your stomach for GERD. If you are regurgitating a lot, this will definitely help painful regurgitation/reflux episodes. However, since starting this drug, I occasionally get panic attacks and get severe anxiety despite never having anxiety issues my entire life. You have to weigh the pros and cons."

3 / 10
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4 Report
  • hol...
  • Taken for less than 1 month
  • May 14, 2023

For Urticaria "I have had stomach pain, uneasiness, and awful gurgling sounds in my belly for days. Diarrhea also. Just an overall unwell feeling after being on this for 3 days. My doctor put me on it to boost my Zyrtec and Allegra meds. I'm throwing them away tonight."

1 / 10
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4 Report
  • doy...
  • Taken for less than 1 month
  • November 17, 2021

For GERD "Took it for COVID nausea/GERD and felt super drowsy 30 min. after taking it. Then anxious and paranoid for the rest of the night. My stomach was super bloated with tons of gas and pains more than without it. I've had diarrhea this morning, cried, and had a heart palp. My son took some last night as well and burped so much. Even though the half-life says 2-3 hours, I definitely believe that the side effects last longer. Drinking lots of water to get this crap out of my system. This stuff should be discontinued. Our pedi even said there were no side effects with this... everything has a side effect. Was $20 too."

1 / 10
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6 Report
  • doy...
  • Taken for less than 1 month
  • November 17, 2021

For GERD "Took it for COVID nausea/GERD and felt super drowsy 30 min. after taking it. Then anxious and paranoid for the rest of the night. My stomach was super bloated with tons of gas and pains more than without it. I've had diarrhea this morning, cried, and had a heart palp. My son took some last night as well and burped so much. Even though the half-life says 2-3 hours, I definitely believe that the side effects last longer. Drinking lots of water to get this crap out of my system. This stuff should be discontinued. Our pedi even said there were no side effects with this... everything has a side effect. Was $20 too."

1 / 10
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6 Report
  • Kar...
  • April 7, 2021

For GERD "I started taking this medication 3 days ago, and I’ve had really bad side effects. I’ve had diarrhea, headaches, anxiety right after I take it, and joint pain, especially in my arm and my back. My doctor said I had to continue taking this medication, as it has been helping with my stomach acid, but it takes me a while to not feel the side effects of this medication."

3 / 10
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6 Report
  • Hal...
  • Taken for less than 1 month
  • December 17, 2021

For Indigestion "Taking it for some days, one 40 mg dose doesn't seem to be sufficient, if I take it in the morning, by late afternoon I start to feel a little burning again. Side effect-wise, I have anxiety, dizziness, and nervousness. Not worth the hassle, better to stick with antacids or PPIs."

4 / 10
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1 Report
  • Hal...
  • Taken for less than 1 month
  • December 17, 2021

For Indigestion "Taking it for some days, one 40 mg dose doesn't seem to be sufficient, if I take it in the morning, by late afternoon I start to feel a little burning again. Side effect-wise, I have anxiety, dizziness, and nervousness. Not worth the hassle, better to stick with antacids or PPIs."

4 / 10
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1 Report
  • 88k...
  • February 1, 2017

For GERD "Since taking this, I have had extreme anxiety, difficulty sleeping, and unable to eat. Has anyone had this problem?"

2 / 10
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120 Report
  • Szu...
  • Taken for less than 1 month
  • January 16, 2021

For GERD "I will never take famotidine again. I felt absolutely horrible! Made me super dizzy, anxious, and insanely tired. I was only taking the 20 mg dose."

1 / 10
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33 Report
  • Rob...
  • August 22, 2021

For GERD "Made me unwell at just 20 mg before bed - anxiety, raised BP, dizziness, migraine lasting days, near constant gas and gastrointestinal upset. If you take this, look out for unexplained migraines."

1 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.