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Estradiol for Gender Dysphoria User Reviews

Brand names: Estrace, Estradiol Patch, Estrogel, Dotti, Climara, Divigel, Vivelle-Dot, Lyllana, Femring, Minivelle, Estraderm, Delestrogen, Alora, Depo-Estradiol Evamist Elestrin Menostar Estra Pellets …show all brand names

Estradiol has an average rating of 10.0 out of 10 from a total of 5 reviews for the off-label treatment of Gender Dysphoria. 100% of reviewers reported a positive experience, while 0% reported a negative experience.

Estradiol rating summary

10.0 average rating out of 10

5 ratings from 6 user reviews.

Compare all 6 medications used in the treatment of Gender Dysphoria.

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  • quiet...
  • Taken for 2 to 5 years
  • November 29, 2014

"After spending over two decades without any treatment, I sought help for my transsexualism; my doctor first prescribed spironolactone, followed by estradiol. It took a bit of time to find the proper dose to balance my estrogen levels, but patience paid off-no negatives! With estradiol, I've finally been able to start building a life for myself!"

10 / 10
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57 Report
  • jessn...
  • Taken for 1 to 6 months
  • November 5, 2018

"Estrogen. It's the best estrogen. Makes growth of breast tissue. But seriously, I can't recommend estradiol enough. I've been taking it sublingually for around 4 months now (2 mg daily for the first 3 months, increased to 4 mg last month), and I feel like an entirely different person. My skin feels so much softer (even though it's still just as dry >:( ), and I've noticed a fair bit of breast growth (they look a bit bigger but feel much different due to an increased amount of tissue), as well as more fat on my face. The one downside is the mood effects; my emotional lows are pretty low. Luckily, my highs are much higher than they ever were before. I'd recommend any trans woman get on estradiol ASAP (provided they're not on it already, haha)."

10 / 10
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35 Report
  • Delila...
  • Taken for 2 to 5 years
  • August 31, 2015

"So I started transitioning at 18, and after a lot of research, I settled on Premarin as it's the closest to organic estrogen. After 2 years on that, I gained too much weight for myself to continue without risking blood clots or a stroke. My doctor said, 'You're switching to estradiol.' I was like, okay. After maybe 3 weeks, when my sex drive came back and my weight went way down, I knew I had made a grave mistake years ago. This may be synthetic, but it's most customly fit for humans. Then I started developing again. This med has changed my life for the better."

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44 Report
  • regina
  • Taken for 5 to 10 years
  • December 29, 2020

"I used esteogen in combination with spiro for 8 years with no side effects ended up with a solid 40 c cup size would like to go back on it to get bigger. I used 2mg twice a day, 200 mgs of spiro and 200mgs of prometrium."

10 / 10
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9 Report
  • scigirl
  • Taken for 6 months to 1 year
  • November 28, 2021

"Turned me into a girl. Now I'm very pretty and don't want to die every day of my life. No downsides. 10/10"

10 / 10
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18 Report
  • evaraud
  • Taken for 1 to 6 months
  • May 26, 2022

"I'm three month on estradiol and cypro. My skin is much softer, my breasts started to develop, my odour is changed, my hair is less oily, i'm so happy with that!"

10 / 10
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5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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