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CombiPatch and Depression: What Users Say

Depression: mentioned by 3 users (5.1%)

Based on user experiences from 59 CombiPatch reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 22.0%
anxiety 16.9%
bleeding 13.6%
insomnia 11.9%
night sweats 10.2%
spotting 8.5%
cramps 6.8%
vaginal issues 6.8%
bloating 5.1%
depression 5.1%

Reviews for CombiPatch

  • Lil...
  • Taken for less than 1 month
  • October 23, 2024

For Postmenopausal Symptoms "I’ve been on CombiPatch for 3 weeks. I got it in May 2024 but only had the courage to start in October 2024. I had explant surgery mid-May, so I decided to wait a month or so. Then I got cold feet. In September, my symptoms of menopause were hard to ignore. Anxiety and despair were the worst part for me, and I wasn’t even sure anymore if my hot flashes were causing the despair or if the despair was causing the hot flashes because they always came in pairs. Either way, I knew it wasn’t normal, so I put the first patch on. The first night, and until last night, I was awake 2 to 4 times every night, and the hot flashes joined me every time. I almost stopped. The 4th week now, and my first full night of sleep with no hot flashes was last night. I did go to sleep at midnight, which was 2 hours late for me, but I woke up at 8:30, so it’s great. I did notice some more energy, and my husband attested that my mood is much better. Will I renew my prescription? Not sure. Still afraid of reports of breast cancer."

8 / 10
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7 Report
  • JMa...
  • Taken for 1 to 6 months
  • December 14, 2018

For Postmenopausal Symptoms "I was diagnosed with sudden early menopause. Severe migraines (worse than I ever had), anxiety and panic attacks, insomnia (barely sleeping), depression, and night sweats. I really started feeling 90% better within a couple of weeks. I’m sleeping. Anxiety is minimal, and I’m sleeping again. Minimal side effects, but I’ve had bloating and bad indigestion."

8 / 10
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27 Report
  • KMa...
  • Taken for 10 years or more
  • July 27, 2021

For Postmenopausal Symptoms "I was on CombiPatch for many years but had to go off of it about a year ago after retiring. Unfortunately, Medicare does not cover CombiPatch. Although I am not sure that it is totally due to going off CombiPatch, I have experienced many changes over the last several months. Those include the return of hot flashes, difficulty sleeping, extreme memory loss and brain fog, irritability, a sense of sadness, possibly depression, achy joints, and just no joy in my life. I spoke to my GYN about it at my annual yesterday. The out-of-pocket cost of CombiPatch for me would be almost $230 a month, and I cannot afford that. Due to this, we are going to try a generic estrogen patch and an oral progesterone tablet. I’ll see how that goes, and if this does not relieve some of my symptoms, I would appreciate someone who is knowledgeable about how I could possibly get CombiPatch from Canada. I have no idea how this works, and I want to appreciate the information if someone can please help me. Thank you."

8 / 10
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16 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.