CombiPatch Interactions
There are 439 drugs known to interact with CombiPatch (estradiol/norethindrone), along with 23 disease interactions, and 9 alcohol/food interactions. Of the total drug interactions, 74 are major, 339 are moderate, and 26 are minor.
- View all 439 medications that may interact with CombiPatch
- View CombiPatch alcohol/food interactions (9)
- View CombiPatch disease interactions (23)
Most frequently checked interactions
View interaction reports for CombiPatch (estradiol / norethindrone) and the medicines listed below.
- acetaminophen
- albuterol
- amlodipine
- atorvastatin
- bupropion
- Celebrex (celecoxib)
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- folic acid
- gabapentin
- hydrochlorothiazide
- hydroxyzine
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- losartan
- metformin
- methotrexate
- metoprolol
- omeprazole
- prednisone
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
CombiPatch alcohol/food interactions
There are 9 alcohol/food interactions with CombiPatch (estradiol / norethindrone).
CombiPatch disease interactions
There are 23 disease interactions with CombiPatch (estradiol / norethindrone) which include:
- abnormal genital bleeding
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- breast malignancy
- liver disease
- thromboembolism
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- hyperlipidemia
- weight gain
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More about CombiPatch (estradiol / norethindrone)
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- Side effects
- Dosage information
- During pregnancy
- Drug class: sex hormone combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.