Vyepti and Migraine: What Users Say

• jan...
• Taken for 1 to 6 months
• December 9, 2022

For Migraine Prevention "I have chronic daily migraines and have taken all three injectable CGRP medications: Emgality, Ajovy, and Aimovig. I sort of had my chronic daily headaches at a half-decent place, but this medicine was supposed to help in conjunction with the Botox and oral preventives I'm already on to take care of the last remaining symptoms. I had the infusion of 100 mg infused over half an hour. I was fine for about 4 hours, I want to say, and my cheeks and face got so red that my brown-colored blush didn't show. I felt extremely nauseated and like I was going to vomit, not to mention horribly physically sick and weak. It also gave me a migraine, and they worsened for about 10 days after. This is, for me anyways, one of the worst medications I have ever taken for the prevention of migraines, and the side effects are a lot worse it seems than advertised. I felt exhausted and gained weight as well, at least these effects are wearing off. I won't take a CGRP med ever again. If they work for you, great, but they're overrated."

• San...
• Taken for 1 to 6 months
• September 13, 2022

For Migraine Prevention "I have had migraines since childhood. About 12 years ago, I began to get ocular migraines and migraine vertigo. It got to the point where I was having at least one episode a day. I have tried every med, every device, Botox, acupuncture. The situation remained chronic. With time, I was down to about 15 or so a month, but I cannot attribute the diminishing to anything specific. Eventually, I was put on Aimovig, but after about a year, it didn't appear to work. I was changed to Emgality. Same thing. After a while, there was no improvement. I was put on Vyepti. Minutes after the first infusion, I had an ocular migraine, and the incidents of aura just kept increasing. My doctor has prescribed 300 mgs, up from 100. The co-pay on Medicare is over $1,000. Impossible! Ridiculous! I don't think this class of drugs works for me. Very disconcerting. I am going to give up on meds for a while."

• mrh...
• May 18, 2024

For Migraine Prevention "During my second infusion that was 300mg, I got a migraine. During my first 3 months of 100mg I saw improvement in weather-related triggers and odors. But I was more light sensitive, especially to the TV. My doctor gave me Ajovy samples to supplement the Vyepti unit I could go to 300mg."

• Itc...
• Taken for less than 1 month
• June 16, 2022

For Migraine Prevention "Not so great, I had an allergic reaction and an ongoing migraine for days accompanying the allergic reaction. I am allergic to a lot of things, though. 100 mg dose."