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Duloxetine for Diabetic Peripheral Neuropathy User Reviews (Page 2)

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Reviews for Duloxetine

Commonly mentioned side effects
  • hem...
  • April 6, 2009

Duloxetine "Cymbalta has been a lifesaver for my diabetic neuropathy. In just a few days, the pain and discomfort went away. The only problem I am facing with Cymbalta is insomnia, even in combination with Xanax 4 mg and Vistaril 150 mg."

9 / 10
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35 Report
  • Mdo...
  • Taken for less than 1 month
  • March 5, 2022

Duloxetine "My issues are severe anxiety, severe depression, and neuropathy. I had suicidal thoughts with Lexapro, so I decided to try Cymbalta. It gave me jaw pain and a weird taste and smell when starting it, but not bad effects. It helped my crying spells stop and seemed to slightly increase depression. I was on 30 mg. However, it made my panic disorder and anxiety skyrocket. It really helped neuropathy and phantom pains I’ve been having. But the heightened anxiety I couldn’t stand, so I had to go off of it. It gave me a weird hypersensitivity feeling."

6 / 10
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6 Report
  • kat...
  • August 6, 2010

Duloxetine "I was very unsteady on my feet. At first, some of the pain was resolved, but it didn't work. Even though my feet were not swollen, they felt that way-a very tight feeling. It felt like I was walking on balloons, a terrible feeling, and I was afraid to walk with that unsteadiness. Didn't work for me. Since then, I have been on many different medications. Neurontin didn't help, amitriptyline didn't help, Lyrica didn't help. I am on nortriptyline now with a pain patch. The fentanyl patch really helps, but I don't want to stay on this forever, so I'm trying different medications. I am only supposed to leave the pain patch on for 3 days and found with the new medication, nortriptyline, I can go 5 days. So I am hopeful here."

3 / 10
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25 Report

Frequently asked questions

  • No ...
  • Taken for less than 1 month
  • July 11, 2016

Duloxetine "I have an amputated left arm. I have horrible nerve pain. The doctor I just saw started me on Cymbalta. I have only been on it a week and have not noticed any difference yet. How long does it take for it to work?"

2 / 10
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19 Report
  • Pet...
  • Taken for less than 1 month
  • October 17, 2017

"Started on 20 mg per day, increasing after a few weeks. At first, I had the expected nausea, dizziness, and feeling of being slightly out of it. However, I was told to push through and give them “time to settle.” Mistake! My symptoms quickly worsened to hot flushes with profuse sweating and a pounding heartbeat, where just being inside the house was way too warm. Then, the mental confusion worsened to the point where I couldn’t even work out simple things like how much money to give when I went shopping. I was getting very confused and clumsy, dropping things and tripping over my own feet. Finally, I began losing control over my upper body. It would freeze up solid with every muscle rigid, and there was nothing I could do to relax."

1 / 10
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6 Report

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  • Ton...
  • March 23, 2012

"I have severe diabetic neuropathy in both feet, and Neurontin seemed rather ineffective. The pain was a combination of burning, needles and pins sensation, and severe knife stabbing sensations intermittently in both feet. I started taking Cymbalta over a year ago, and it has significantly reduced the sensations and pain, making them tolerable. I initially noticed a loss of appetite, which was a blessing in disguise for me, and I lost 25 pounds before the anorexia disappeared. I have several severe disorders that require close monitoring of my blood, but overall, Cymbalta has been a godsend to me."

8 / 10
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6 Report
  • Mat...
  • Taken for 1 to 6 months
  • March 7, 2023

"Seems to have been effective in dealing with hand pain and tingling, but has caused constant nausea, dry mouth, and diarrhea. Reduced to 48- and 72-hour intervals, which deal with nerve pain but always cause side effects."

3 / 10
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1 Report

More FAQ

  • Bik...
  • Taken for 1 to 2 years
  • August 9, 2024

Duloxetine "I was given Cymbalta for depression after my doctor asked how long I had been taking Celexa. When I replied, 'since about 2006,' and it was now 2020, I am guessing that prompted her changing me up. I too have neuropathy, supposedly type II diabetes-related. I am still not sure that is what I have going on, but that is another story... I was placed on Cymbalta for depression, NOT pain. I am unaware of Cymbalta having pain-relieving properties. I DO know that Cymbalta or Duloxetine (sp) was originally formulated as an anti-seizure medication. I believe that they discovered it was effective enough to begin prescribing it specifically for that purpose. I also take Gabapentin for nerve pain. The stuff works, but some of the side effects are bad, one of them goes unaccepted as being related to Gabapentin: accelerated tooth and root decay. Numerous reports from people with the same symptoms after beginning Gabapentin."

7 / 10
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0 Report
  • Anonymous
  • September 6, 2010

Duloxetine "Cymbalta lessens the burning pain in my feet that used to wake me up and keep me awake at night. It often relieves burning pain almost completely."

8 / 10
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81 Report
  • Alf...
  • Taken for 6 months to 1 year
  • July 25, 2019

Duloxetine "I had frequent 'attacks' of neuropathy pains, and after a few months of using Cymbalta, the cycle of attacks drastically reduced."

9 / 10
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32 Report
  • Mom...
  • July 7, 2014

Duloxetine "Can't live without it."

10 / 10
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55 Report
  • Dun...
  • January 23, 2017

Duloxetine "I've been taking Cymbalta for 10 years for neuropathy. I didn't know how effective it was until I decided to stop taking it. My foot felt as if it were in hot coals. I love it."

10 / 10
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46 Report
  • Ann...
  • Taken for less than 1 month
  • September 1, 2019

Duloxetine "Within one week, I suffered a reaction to the drug, with hives progressing quickly."

1 / 10
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30 Report
  • HAP...
  • June 26, 2009

Duloxetine "Works great on my nerve pains, due to diabetes."

10 / 10
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51 Report
  • Rob...
  • Taken for 2 to 5 years
  • January 2, 2014

Duloxetine "Increases blood sugars. x 2 higher than when not taking it."

1 / 10
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45 Report
  • Anonymous
  • August 12, 2012

Duloxetine "Did not work for me. I had nausea, abdominal and stomach pain, loss of appetite. I lost 5 lbs. in less than a week."

1 / 10
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46 Report
  • No ...
  • May 28, 2016

Duloxetine "Sort of worked, but I was sleeping all the time. 12 - 14 hours per day and then could not move the rest of the day. Had to stop after 10 days of being a zombie."

5 / 10
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28 Report
  • Lis...
  • March 7, 2016

Duloxetine "Made me sick first day: nausea, dizzy, vomit, sweating, high blood pressure."

1 / 10
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22 Report
  • Anonymous
  • February 25, 2009

Duloxetine "Caused me to have serotonin syndrome."

9 / 10
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33 Report
  • GTa...
  • September 20, 2019

"After one week of taking the drug duloxetine, I broke out in a rash. The medication I was given to heal the rash caused the spots to turn to peeling skin."

1 / 10
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5 Report
  • Spa...
  • August 8, 2022

Duloxetine "Cymbalta works for neuropathy."

6 / 10
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4 Report
  • Flo...
  • Taken for less than 1 month
  • October 15, 2021

"Just wondering how long this medication lasts in our bodies after taking one week?"

4 / 10
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2 Report
  • Ros...
  • Taken for 6 months to 1 year
  • January 27, 2022

Duloxetine "Didn't do anything for pain for me, I might as well have taken an aspirin. It doesn't seem to work for pain for everyone."

1 / 10
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3 Report
  • Jos...
  • Taken for 1 to 6 months
  • June 18, 2014

"Causes erectile dysfunction and raises blood sugar x 2 times."

1 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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