Duloxetine for Bipolar Disorder User Reviews (Page 2)

• Anonymous
• November 14, 2011

Duloxetine "I have been taking Cymbalta for the second time after going off it cold turkey 5 months previously (wouldn't recommend it). I have found in the last week feeling very hyped up again. The depression is not as bad, but the hyped-up feeling is becoming hard to control. I'm on the 30 mg. Only sexual disinterest and constant feeling of wanting to go to the toilet are a little frustrating."

• Ooa...
• September 21, 2009

Duloxetine "I have been on Cymbalta 30 mg for the last 5 days. I noticed a lot of side effects, good and bad. The bad ones include insomnia, dizziness, nausea, and dry mouth. The two good side effects were less urgency to urinate and fewer hunger pangs. I used to run to the bathroom every hour and almost constantly eat. My mood is improving, and I seem to be coming out of my shell. In a few more days, my dose will double, and I am sure this medication will work. I feel as if I am on the right path to becoming who I used to be years ago."

• Sar...
• October 11, 2009

Duloxetine "Cymbalta was a wonderful mood elevator and controlled my swings especially well at first, but the emotional blunting and sexual disinterest and malfunction were devastating to my relationship with my mate. After several months of taking Cymbalta, it quit working so well, and when my dose was increased, the emotion blunting and other side effects turned me into a walking, talking zombie."

• PC1...
• Taken for 1 to 6 months
• June 25, 2024

"This medication has honestly saved my life. I’ve been struggling with bipolar disorder for over 10 years and was honestly losing hope until I was put on this. It has completely stopped my depression and extreme depressive episodes. I haven’t felt like this in years. The only negative experience is the first week in taking it, you may have a headache, which has been absolutely worth it ever since. I’ve now been on it for 2 months, and everything has been great."

• Anonymous
• October 17, 2009

"After a few years on SSRIs with recurring switches to hypomania, I was put on Cymbalta and Lithium. First, there was a great antidepressant effect, but soon after I was told to raise the dose, I switched into a period of mania, making me aggressive. Since two years ago, I haven't taken any antidepressants and have not been hypomanic/manic a single time."

• Anonymous
• Taken for less than 1 month
• March 17, 2022

"I began at 30 mg. When it started to kick in, I essentially felt like I had taken some MDMA/amphetamine. Hot flashes, panic, uncontrollable sweating, and even explosive diarrhea to the point where I had lost multiple pounds over the course of one night. After that had mostly subsided, I could not stop grinding my teeth and moving around like I was coming down from some strong stimulant. The twitching was unreal, as were the intrusive thoughts. I was extremely exhausted but had so much trouble getting to sleep. For some reason, I had taken it the following night before I went to sleep. I awoke in a panic, feeling all of the blood pulse throughout my extremities and my vision so blurry that it was a struggle to make out anything around me. I ended up in the ER with stroke-level blood pressure and severe hallucinations. The hallucinations and severe anxiety persisted for about three days after taking it for two. Certainly not a fun time!"

• Bet...
• February 2, 2022

"Saved my life. I only use 10 granules in the morning and ten granules at night. Breaking open the capsule per my doctor, I was in major depression. I have been able to get out of bed and do things. I can eat, sleep, and go to the bathroom okay. Seven years looking for a solution. I also suffer from fibromyalgia and neuropathic pain in my feet, which is why I was prescribed this medication, even with the risk of mania. Tried the super low dose, and it kicked my depression to the curb. I still have pain in my feet, but body pain goes away. I don't even care about the foot pain because my depression has finally lifted, and I don't feel like ending it all anymore. So for me, it is a miracle, and I am so happy to be alive and not have done anything. Prayers to everyone out there suffering with mental health issues, you are not alone."

• Gfe...
• August 19, 2009

Duloxetine "I find this new antidepressant the best I have tried so far, and I have tried so very many. I give it 95/100, only because it gives me really, really bad hot flushes through the night, which wake me up, and I toss and turn and get hot and cold - all night."

• Ton...
• Taken for 1 to 6 months
• May 3, 2019

"I have bipolar type 2 with mixed episodes and just been taking duloxetine for 3 weeks and got very manic. I had to stop them and really want to warn others with mixed episodes to not take these. All antidepressants give me hypomania, but Cymbalta and Wellbutrin have been the worst. I take Lamictal and olanzapine as well."

• ano...
• October 4, 2015

"I was on both Cymbalta and duloxetine, and I would swing in and out of black moods and get very angry and uncontrollable. I'm a small girl, 5'3, 114 lbs at the time, and it took three full-grown men to get me held down several times. We're now trying new medications after we discovered I was having seizures for months before starting the meds. It is a great medication to be on if it fits with you and your current medications. Do your research thoroughly."

• Bea...
• Taken for 2 to 5 years
• August 15, 2022

"Over nearly 50 years, I have taken many antidepressants, always with lithium. Each faded in effectiveness over time. All had unpleasant to serious side effects. No side effects from Cymbalta. Tapered lithium slowly over six to eight weeks as symptoms began to lift with Cymbalta. My new sense of authenticity is, in part, a gift of this med. I credit myself for my lifetime of work toward goals of living."

• m11...
• June 2, 2009

Duloxetine "I really like Cymbalta. It eliminates my anxiety and levels me out. What I don't like about Cymbalta: night sweats and general muscle fatigue. I laughed when I saw that it is a treatment for hot flashes. I have been on numerous antidepressants, and that is one of the main side effects."

• Kat...
• Taken for 5 to 10 years
• September 25, 2021

"I can only say good things about Cymbalta. I have been on it about 8 years. It was prescribed for depression and a little fibromyalgia (I was pain sensitive to touch). Well, it worked wonders on both accounts. At one point, I felt I need something extra, so my GP upped me to 120 mg, and I felt no different. I worked in pharmacy, so I knew 90 was the max you could absorb in one dose. So, I went back to 60 mg. I had no side effects that I noticed. I had to change GPs and was sent for a psych evaluation. I was finally properly diagnosed with bipolar disorder mixed episodes. Occasionally, I have a tiny bit of mania/depression. I had already been taking trazodone for sleep. So between the three, I'm stable, I have moments but not often. I remind others there is no cure or magic pill. Meds help you manage it. Cymbalta is great!"

• sgo...
• Taken for 2 to 5 years
• June 20, 2021

"Duloxetine did nothing for me but induce my mania and depression. I was also misdiagnosed. My emotions felt a little torturous because I couldn’t control my emotions at all. I fell into depression, being slightly triggered, and tapering off this medication, it sucked so badly. It’s been the worst, with my mood swings, crying spells, hypomanic episodes, depressive ones became triggered, etc., etc."

• Blu...
• Taken for 1 to 2 years
• May 7, 2020

"I'm also on Duloxetine, Wellbutrin, and Lamictal. I feel flat. I miss being manic. When manic, I tend to lose a bunch of weight, drink excessively, buy a lot of stuff, and be sexually promiscuous. Lemme tell ya, that last one was a fun 9 months. I've been in a depressed/flat state just about 2 years now. I changed my lamotrigine dose (I'm such a horrible, non-compliant patient) a couple of months ago and eased myself down from three pills to one pill per day. (I think it's 30 mgs maybe). I haven't noticed any difference yet though."

• Ett...
• Taken for 2 to 5 years
• December 11, 2020

"I used to be on Cymbalta and loved it! Then I was put on Seroquel and loved it too. But which one, to me, is the absolute best? Seroquel, in my opinion, though I'm not on it now, and trust me... I'm feeling it! And why? Simple. Because I wasn't watching my supply so as to know when it was time to replenish it. But I'm planning to, and I'm certain that I won't run out of my Seroquel again!"

• Lun...
• January 29, 2016

"I have been battling with major depression since I was a child. I have been on many different types of medications over the years. I also have a major case of obsessive-compulsive disorder, and as I'm getting older, it has been getting severely worse. Everything has to be in perfect order. I spend hours upon hours a day making sure everything is in order. It's so bad that I cannot even have garbage in my garbage cans, if so, I have to clean the cans immediately. It has become so bad that it cuts into other daily activities such as spending time with my wife, family, and friends. Some days I do not even attempt to get out of bed. Some days I will sleep for well over 24 hours. These are the medications I'm taking daily. I take 150 mg of Lamotrigine."

• Fri...
• Taken for less than 1 month
• November 15, 2024

"I'm just starting but have a lot to say and will be back later with this name 'Friend.' First, if we are really bipolar, we have a big risk of mania no matter what antidepressant we take. One must take 500 mg Dapakan/Valproate with this, just as one person said. Then: we all have something weakening us, an odd psychic something, or mood, or another health problem. This is the safest antidepressant, but we should start by opening a 20 mg capsule and taking 1/4 of the granules for several days, unless you don't mind strong constipation, three sleepless nights, feeling excited when you need calm or something worse that we read here. I started with 1/2 a capsule morning and night as one person suggested. That's too much, and starting on more is asking for very unnecessary side effects. Most of these negative reviews come from haste, I assure you. I'm healthy, not very depressed or abnormal, but old. There's something like that for everyone and odd differences in make-up. May many more succeed!"

• MGO...
• September 16, 2011

Duloxetine "While on Cymbalta, I became suicidal."

• Anonymous
• August 20, 2009

Duloxetine "Made me too tired to function."

• THa...
• March 6, 2009

Duloxetine "Cymbalta has really helped me calm down and figure out what my problem is with my psychologist. Thank God for Cymbalta."

• Caz...
• February 7, 2017

"Awful. Sent me high as a kite, chaotic, impulsive, and suicidal. It was being administered without mood stabilizers, though, and at a high dose."

• Mar...
• Taken for 1 to 6 months
• November 5, 2023

"Since I started Cymbalta, it has helped me greatly have more energy and want to be more social."

• mik...
• April 22, 2021

"Hypermanic from it if I take 60 mg, even 30 mg, so no, this medicine is not for me. In the beginning, it helped my neuropathy, but now I am getting hypermanic on it."

• Anonymous
• November 10, 2009

Duloxetine "I really did think that it was a pretty good medicine. Had no problems with it."