Dulaglutide and Nausea: What Users Say (Page 4)

• Cat...
• March 8, 2017

For Type 2 Diabetes "First week - I was cold all the time, and I'm never cold. I had flu-like body aches. I had nausea after the first day. By the fourth day, I had vomiting and diarrhea for about 8 hours straight. Today is one week after the first injection, and my stomach is still not the same. I will NOT be taking another injection. Also, for several days, horrible belching, a rotten egg smell."

• Don...
• Taken for 1 to 6 months
• October 9, 2019

For Type 2 Diabetes "Review 2, week 10. I did ride it out, and the nausea and lack of appetite did subside at around week 4. However, week 8/9 it came back. Not sure why. Wasn’t as bad as the first 3 weeks. I’m due for a review at the doc's end of the month, so will see how it’s helped my A1c. Weight loss has been amazing. Just don’t think it’s the healthiest way to lose weight, due to not being able to eat."

• One...
• Taken for less than 1 month
• December 30, 2015

For Type 2 Diabetes "Today I started week 3, and here are the 3 biggest side effects I have been experiencing: 1. Nausea - Comes out of nowhere. It's comparable to a mid-level sea sickness-type feeling. At times I feel like I need to vomit; however, I came very close once and got past it. 2. Loss of appetite - I'm never hungry. Although I have to eat, I have made better choices when I do. My cravings for anything sweet have diminished altogether. 3. Heartburn - Just like the nausea; it comes out of nowhere and I want to drink a gallon of Pepto to help, which I did try once and I couldn't. Overall, like with any medication, there are going to be side effects. Some more severe than others, but try it and see how it might work for you. Best of luck!!"

• cat...
• Taken for less than 1 month
• January 16, 2016

For Type 2 Diabetes "I have taken a 1.75 mg shot of Trulicity, and I'm going to beg my doctor to take me off of it. I was nauseous from day 2 onward, and today (7 days later), I'm vomiting, have explosive diarrhea, and horrible, foul belching. This is the same exact reaction, down to the belching, that I had while taking Metformin. If you are taking Trulicity and Metformin, I'm not sure how you are even alive. My A1C, tested twice in the last 6 months, is 6.5, and that was while taking Januvia, Pioglitazone, and Farxiga. My doctor replaced the Januvia with Trulicity to help improve my daily high readings. Today is shot day...not happening. As I type, I'm about to puke..."

• Ste...
• June 22, 2017

For Type 2 Diabetes "September 2016, I tried the higher dose but could not tolerate it. Recently, my doctor had me try the lower dose. I was able to tolerate it and then titrate to the higher dose. Initially, the nausea and indigestion were significant, but I waited it out and it got better. I lost 8 pounds the first month. Had I not started on the lower dose, there is no possible way I could have used the medication. My sugars average 112 over the past month, and those are not even fasting. I really like the medication. It's a matter of just toughing it out."

• CeC...
• Taken for 1 to 6 months
• September 12, 2016

For Type 2 Diabetes "My blood sugar levels have definitely come down, from the 250-350 range to the 90-150 range. This med works great for that. However, 5 weeks in and I'm still having side effects that can be hard to deal with. The nausea has lessened, the burping is less, but I still get stomach cramps the first day or two after an injection. I'm also getting muscle weakness, muscle pain, extreme fatigue, joint pain, I'm off-balance, can't concentrate, jittery, woozy, and my peripheral neuropathy seems worse. I definitely eat less. I might be hypersensitive, and every little ache and pain gets blamed on the Trulicity, but since I started it I just don't feel good. I'm not sure if the side effects are worth the good numbers, but I'm hanging in there hoping to adjust!"

• Aci...
• Taken for 1 to 6 months
• January 5, 2019

For Type 2 Diabetes "I've been taking Trulicity for about 2 months. Nausea, horrible acid reflux, stomach pain and bloating, constipation. I'm scared to eat too much, so I suppose I've lost some weight, but at what price? I'm stopping this poison. I can feel fine and literally in 3 minutes, then be vomiting water."

• Tra...
• Taken for 1 to 6 months
• February 11, 2019

For Type 2 Diabetes "I was worried about this injection, which proved to be simple and painless. What I wasn't ready for were the side effects: nausea that lasted 1 month and limited my abilities to go to work, diarrhea that was constant and explosive, which also limited my daily activities and lasted 3 weeks, followed by dehydration, dizziness, and foggy thinking. I had just started a new job, so this was a bad experience for me. I did, however, lose weight due to the nausea and diarrhea."

• Deb...
• Taken for less than 1 month
• May 23, 2019

For Type 2 Diabetes "If you want to feel like you are dying, this Trulicity is the drug for you! This drug is a disgrace and shouldn’t even be allowed to be on the market! SERIOUSLY! Worst medication I have ever taken! Pray they don't delete my post! I took this drug this morning, given to me by my doctor. I have had severe, nonstop, excruciating pains throughout my stomach, vomiting, nausea, and diarrhea! I looked over side effects, and it says exactly that - plus you can get deadly thyroid cancer. Do yourself a favor and REJECT THIS DISGUSTING, DEADLY MEDICINE!!"

• Dlr...
• Taken for 1 to 6 months
• August 15, 2017

For Type 2 Diabetes "Took first shot in doctor's office 2 weeks ago, 75 mg, and started feeling a little unwell that night. Next day, extreme nausea, belching, just sick. Finally subsided night before second shot. Took second shot, helps with bringing numbers down, though. Side effects of fullness - you have to hydrate and eat smaller meals. Hope this helps someone. It does get better. Hope. Took third shot, experienced bad nausea and vomiting."

• Cha...
• Taken for less than 1 month
• December 1, 2018

For Type 2 Diabetes "Trulicity is the worst. I started on Saturday after Thanksgiving. On Monday at 4 pm, I started feeling bad. Got home from work, diarrhea set in, very nauseous, belching rotten eggs, the smell was horrible, pain on the left side, and I was very cold. I went to bed, got up the next morning, very, very sick. Went to work, coworkers saw me and said, 'Are you OK?' I had to leave early, missed work the next day. Rapid heartbeat by Thursday, a week later still not eating, very dizzy. Will never take again - nightmare. Quality of life sucks."

• Per...
• Taken for 6 months to 1 year
• August 22, 2016

For Type 2 Diabetes "Been on Trulicity over 8 months, 6 or so months ago, thought I had pancreatitis, stomach pain so bad, sulfur burps, stomach swollen with gas, nausea, going through tests to find out what's wrong, then back pain that I've never had before, so severe. Already need hips and knees replaced, but knee pain got worse, nausea every day and night, sipping ginger ale just to survive, can't eat, except for cheese nips...not till today did I realize all this may be caused by Trulicity!! Thought I was dying!! Ugh, happy to have found this site."

• Typ...
• Taken for less than 1 month
• April 14, 2016

For Type 2 Diabetes "Starting on day one, I was using the bathroom at least six times a day, with the urge to go hitting me suddenly and urgently, with the end product (pardon me) being a thin gruel. I had no appetite, which made it harder to drink enough water to keep up with my fluid loss. By day three, I was nauseated and so dehydrated that my blood pressure dropped, leaving me weak and dizzy. That's when the vomiting started. The worst it got: one sip of water had me throwing up until nothing came out and then dry-heaving to the brink of exhaustion. I was almost completely bedridden for two days and only just recovered today, having survived on sips of Gatorade. I'm amazed the FDA approved Trulicity. It felt more like rat poison than a promising new drug."

• Ano...
• Taken for 1 to 2 years
• July 21, 2018

For Type 2 Diabetes "Have been on the 0.75 dose for over a year. Endocrinologist wanted to increase the amount, and I said I couldn’t handle the nausea at 0.75. But they encouraged me to continue. I really tried to forge past the nausea, vomiting, and diarrhea. Yes, my sugars have come down, however, since February, they have started to be all over the map. The nausea is much worse, I’m vomiting in my sleep and choking all the time. Irregular periods. Constant diarrhea. Numbness in my feet. Excessive fatigue. Joint pain. Itching all over. Sore throat. And most recently, abdominal pain in my left upper stomach. I’m terrified I’m getting pancreatitis. This is not worth it. My doctor and endocrinologist said I would lose weight on this medication. False. I’ve gained 6 pounds. I’m over it. My kidney function has decreased, I’m now stage 2 chronic kidney disease. I pray the medication isn’t to blame. I also pray that it hasn’t caused permanent damage to other organs. Don’t use this medication."

• Ter...
• January 19, 2017

For Type 2 Diabetes "I have been on Trulicity (0.75) for about 6 weeks. It has lowered blood sugar about 25 points. I will get A1C in two weeks. The first shot left me with nausea and an upset stomach. That has passed, and now I have no stomach problems. I take the shot at night and am fine by the next morning. It has left me with joint pain in my hands. This pain started the first week, and I still have some joint pain. I keep hoping it will go away. I will see what happens in the next few weeks. I noticed in reviews that other people also had joint pain. Do any of these people have information on how long the pain lasts? In talking with the drug company and pharmacist, no one has any information on this issue. I have lost about 10 pounds."

• Mic...
• Taken for 1 to 6 months
• June 24, 2016

For Type 2 Diabetes "Week 6 update... The first 5 shots (5 weeks), lowest dose of 0.75. I had the usual nausea for a day or two after each shot and loss of appetite... no big deal, as it felt good to NOT be hungry and craving the carbs! Week 6 was this past Sunday. No nausea, but started with the sulfur burps and diarrhea Thursday night. Might not be connected, seeing it is week 6 and NOT week 1 or 2? I am down around 11 - 12 pounds since starting 6 weeks ago. Levels have been running NO higher than 126... UNHEARD of for me :) Also take Metformin XR x2 pills daily. I am soooo anxious to get my A1c level checked in a couple of months :)"

• Mau...
• Taken for less than 1 month
• November 4, 2018

For Type 2 Diabetes "I have struggled with my weight all my adult life, and as Trulicity is recommended before considering bariatric surgery, I took my doctor's advice and administered my first injection yesterday. It will be my last. I don't care if I lose 25 pounds before next week's injection is due, I have never felt this awful before. I read that the side effects tend to wane after a couple of treatments, but I refuse to live through another cycle of the worst heartburn, nausea, and ill feeling I have ever gone through (and I had heartburn through all four of my pregnancies)! I am praying that the one injection has not resulted in irreparable damage to either my esophagus or other organs. I feel so sorry for those who have genuine health concerns that have deemed Trulicity their best hope-I will never recommend it."

• Anonymous
• Taken for 1 to 6 months
• February 11, 2020

For Type 2 Diabetes "I have Type 2 Diabetes, and have not been taking Janumet like I am supposed to. My Endo gave me samples of Trulicity (low dose) to try. This week will be injection #8. I forgot to check my A1C prior to starting it, but I will check it in April. I have lost 17 pounds, with little exercise. I don't have an appetite most days (not complaining), but eat small meals/snacks. When I do eat, I get full quicker, and have noticed a slight nauseated feeling when eating something greasy. I do feel fatigue, but can't totally put that on the medication. My A1C is 6.6, and my doc said that I have to lose 5% of my body weight in order for me to not have to worry about having Type 2 Diabetes anymore! Thanks, Trulicity!"

• Gol...
• Taken for 1 to 6 months
• April 18, 2016

For Type 2 Diabetes "3-month update on Trulicity. When I started, my A1C was at 8 in January. I did have some aches, nausea, heartburn, and headaches. At the end of the three months, I've lost ten pounds, my A1C dropped to 6. From reading other people's experiences and results, I realize that everyone's body and results are different. I wish my A1C was lower, but I will definitely take it. As of right now, I have no longer had nausea or heartburn. I will continue to work on my diet and make better choices, and hopefully next time my A1C will be at a comfortable level."

• Mic...
• Taken for less than 1 month
• July 22, 2019

For Type 2 Diabetes "I started taking Trulicity Thursday after a lot of apprehension due to reading not only bad but very worrying reviews on it. Well, I’m into my fourth day now and can very happily report it’s been fine apart from very slight nausea, which I can live with. I have had terrible trapped wind and burps at nighttime, which has kept me awake, but this is the first night I’m not suffering. My appetite has gone right down, and my sugar levels, although not completely down, are better than they were. To be honest, the very slight effects I have suffered have been nothing compared to the tiredness, sickness, and the feeling that comes with high sugar levels. For me personally, I can only give a positive review as so far, so good and have no real negatives to report. All I can suggest for anyone going onto this medication, it is worth giving a go. It may not suit everyone, but until you try it, you won’t know."

• Sic...
• November 22, 2015

For Type 2 Diabetes "PART 1: Been on Trulicity for approx. 6 weeks (2 weeks at .5, the rest at 1.5). I FEEL LIKE CRAP. No weight loss, but sugars are running low, sometimes too low (60s). The first 2 weeks were like everyone else: diarrhea, heartburn, etc. BUT THIS WEEK IS THE WORST. I couldn't sleep one night due to the heartburn, I'm constantly nauseous and can't eat. Surprisingly, I've been constipated lately and had to take stool softeners. Yesterday (Saturday) I threw up 4 times!! Reading the other comments did help explain the other effects I also have been experiencing. I am EXTREMELY fatigued ALL the time, I'm already on anti-depressants, but this is actually making symptoms worse than before I was on Trulicity. I have constant headaches....."

• Anonymous
• Taken for less than 1 month
• June 24, 2019

For Type 2 Diabetes "On 06/16/19, I took my first injection of Trulicity, and for the first 2 days, I felt good. My sugar levels were staying between 100-130. By the morning of day 3, I was starting to feel nauseated. Then I was starting to belch up a nasty taste in my mouth, like a metal taste, and it smelled like sewage. Then I started to get very bloated and gassy. I could not have bowel movements and could not release any gas out of my stomach. My stomach felt so hard, and it was hurting me so badly. I had a very bad full feeling, and I stopped eating by that Friday morning, which was the 5th day, and I was experiencing very bad indigestion. I took Gas X and Pepcid AC, but no relief at all! I have gone 4 days with no appetite, and I’m getting concerned because of being a Type 2 diabetic. I really think this medication needs to be taken off the market. I have read too many bad reviews with people having the same symptoms. I will definitely NOT be taking this medication again or ever recommend it for anyone to take!!"

• Gol...
• Taken for less than 1 month
• January 23, 2016

For Type 2 Diabetes "Third week on Trulicity and I feel great. Nausea is gone. Only lasted maybe four days from the first injection. Testing my blood sugar, and this morning it was at 85, down from the 150-160s I was used to seeing. Anxious to see what my A1C will be in April. Have also lost some weight. Do occasionally get heartburn. Trulicity makes me watch closer to what I'm actually eating and not just eating like I was before."

• Pig...
• Taken for less than 1 month
• October 3, 2019

For Type 2 Diabetes "I'm on day 10, so I have had two injections. My fasting numbers are really good! No gastrointestinal side effects except mild heartburn. Experienced decreased appetite and have lost 6 lbs so far. I have horrible side effects with metformin in any form or amount. I used to take Byetta with much more severe side effects. Mostly nausea."

• Por...
• Taken for 1 to 6 months
• January 15, 2017

For Type 2 Diabetes "This medicine is awesome! Some stomach issues in the beginning (nausea, indigestion). They do not persist after a few weeks. My mood has improved, as well as less of an appetite. I have not had any hypoglycemic events. Let your dose get to room temperature before injection."