Dulaglutide and Nausea: What Users Say (Page 2)

• Dap...
• Taken for 1 to 6 months
• September 12, 2019

For Type 2 Diabetes "It's been almost 4 weeks now since I've been on the Trulicity 0.75 mg weekly. I did experience some mild nausea and a few headaches, but overall, my experience has been great. My appetite has decreased a lot. I was advised to stay on the 1000 mg of metformin at bedtime by my endocrinologist, which balanced out the constipation and diarrhea. I am, however, gassy... lol... but I can deal with that. I have experienced some weight loss, but I don't know how much. I see it in my clothing, and I feel much lighter. I also have increased energy."

• Nan...
• November 12, 2019

For Type 2 Diabetes "I've been a diabetic for 23 years, and for the last 4 years, I've been all over the charts with my A1C. Dr. prescribed Trulicity last week, I should have read the reviews on this site first. I've been sick the last 4 days! I swear I felt it in my lungs the minute it was injected, then the nausea started. I've been in bed the better part of the last 4 days, but between the cramping, dizziness, diarrhea, headaches, and high blood pressure readings, I've decided it's not working for me. It's not worth the misery. I wanted to give it a chance, but I can't live like this any longer. Any food I put in my stomach feels like a sharp pain, it feels like my insides are turned inside out! I'm 58, and I've quit! Life's too short."

• lst...
• Taken for 1 to 2 years
• April 28, 2016

For Type 2 Diabetes "I've been on Trulicity for 1 year. It has been a miracle medicine for me. I had nausea the first 2 weeks, but no adverse side effects since then. I take a 1.5 shot each week. A1C has improved to 5.6. Hashimoto's and IBS are much improved. Abdominal pain and low blood sugar were gone after 1 month. I have struggled with abdominal pain, IBS, low blood sugar, and morbid obesity for 40 years. I lost 74 pounds this year while taking Trulicity."

• Lyd...
• Taken for 1 to 2 years
• March 23, 2019

For Type 2 Diabetes "I've been taking this drug for over a year now. While it has decreased my A1C to normal, I have experienced nausea the entire time. Diarrhea the entire time, loss of appetite to the point of forgetting to eat, and recently have started to have severe upper stomach pain, especially after I eat. Doesn't matter what I eat or how little or how much. The pain radiates to my back. Been doing a little research, and I firmly believe this drug has caused me to have pancreatitis. All this time, I thought it was normal side effects, but at some point during the past year, I've developed another medical issue because of this drug. I am stopping usage today. I can barely eat anything. I wake up in the middle of the night in pain, and it is starting to negatively affect my day-to-day life. Be careful with this drug and pay attention to your symptoms."

• Ste...
• Taken for less than 1 month
• July 18, 2019

For Type 2 Diabetes "Lucky for us in the UK, meds are all free on the NHS. So, I have now been on Trulicity for 3 weeks. 1st week, awful nausea with tummy ache. Appetite non-existent. 2nd week, similar, but noticed nausea reduced, in fact, it comes and goes in bouts. Not too much bloating, but gassy at times. Bloods down dramatically to 5.5-6.5. Reduced Gliclazide from 2 per day down to half a tablet per day. 3rd week, feeling much better with side effects reduced further again. Weight loss over 3 weeks, average 10 pounds, so very happy. Intend to stay on this for the long term, with exercise, my weight will come off quickly. Very happy with Trulicity, and if you are lucky like me, stay on it. Sorry for all of you who couldn't stick with it."

• Jay...
• Taken for less than 1 month
• May 5, 2019

For Type 2 Diabetes "I started on Trulicity last Monday, and I've been sick as a dog ever since (it's now Saturday night). Within an hour of injection, I was retching at the porcelain altar. Sick to my stomach and stayed in bed the whole next day. Wednesday, I felt good enough to go to the gym and eat lightly, although I still felt slightly nauseous. Wednesday night, I woke up retching again. Sick all day Thursday, and I had a charity dinner to attend that night. Couldn't eat the dinner and went out in the lobby while others dined. Totally miserable! Friday, still sick and weak, foggy brained. Had an appointment with an attorney I was late for because of anal leakage in my khaki pants! Friday night and all day Saturday, I had intense stomach cramps and black liquid diarrhea. Leakage again, had to change pants. Drank half a bottle of Kaopectate, but can't stop diarrhea. I have a concert tomorrow, I don't know if I'll be able to attend."

• gri...
• Taken for 1 to 6 months
• October 20, 2016

For Type 2 Diabetes "I take my 6th dose of 0.75 mg Trulicity tomorrow (10/21/16), and I feel great! The first few doses came with some nausea and a little cramping, but I was expecting it. Now I don't have cramping or nausea, but I notice that my appetite is almost non-existent for the first day or two, so I just remind myself to eat small, healthy meals to keep me from feeling bad. I have lost a total of 18 lbs since starting Trulicity 5 weeks ago, and I went from my blood sugar averaging 200-300 to having blood sugar levels that range from 80-150. I have more energy, and I don't feel like I am in a fog all of the time. It has really made a difference for me so far."

• Kel...
• Taken for less than 1 month
• November 18, 2018

For Type 2 Diabetes "I realize everyone's experience is different, but I was not prepared for this. Nausea, vomiting, and diarrhea 24/7. I have never felt so horrible in my life. It's only been 3 weeks. I can't live like this. I am missing work because I need to get to a bathroom constantly. I've lost 15 pounds. My aunt takes the same dose, and she has had no side effects at all. I am just praying it works its way out of my system soon."

• Anonymous
• Taken for 1 to 6 months
• January 2, 2016

For Type 2 Diabetes "I have been on Trulicity for 12 weeks now. The first 2 weeks I was on the 0.75 mg injection, then went to 1.5 mg. The first 2 days after my injection, I am very nauseated and usually vomit around 4 a.m. My issue is indigestion, and of course, nausea and vomiting. I have found that eating no greasy foods, dairy products, and no eating past 6 p.m. has helped me tremendously in cutting down on the indigestion and nausea and vomiting. My blood sugars are doing great, and my A1C is coming down. I, like so many others, do not have an appetite, and I experience diarrhea often. I have lost 34 pounds so far. I am very happy with the medication, and just learning what you can and cannot eat is the key factor."

• Maw...
• Taken for less than 1 month
• June 2, 2020

For Type 2 Diabetes "Started Trulicity 5 days ago on Thursday afternoon. Horrible night. Horrible indigestion, bloating, nausea, gas, feeling so bad and weak all over. Wanted this medicine out of my body. Late Monday afternoon, began to feel better. Today, Tuesday, still feel better with just some belching. Have to eat little at a time and eat ginger cookies for some leftover nausea after eating. Sugar levels have been lower. Now trying to decide if the same thing will happen with the second dose on Thursday and if I want to do another injection."

• Bea...
• Taken for less than 1 month
• January 26, 2019

For Type 2 Diabetes "One year ago this past October, on my 45th birthday, I was diagnosed with DM 2 out of the blue. As it would turn out, I am one of those poorly controlled individuals. I was started on Metformin 500 mg twice a day, then Glipizide ER 5 added daily with fasting still 450. In December, my readings stayed over 600. This is when I was introduced to 'Trulicity.' Week 1, not bad. Week 2, rougher, pain in the pancreatic region/kidney. More intense waves of nausea/diarrhea. Tolerating. Week 3, debilitating. Nausea, mass diarrhea, which was crippling. I have lost 10 lbs since starting this med on January 7th. My blood sugars have improved, 170s...the lowest it's been in a year, but I have to question, is it the Trulicity or the fact that I can't eat, and when I try, I'm puking my guts out? This has been the worst week yet, so I am done. No more Trulicity for me. I would rather suffer the consequences of poor control than to have an 'improved' blood sugar that is still non-therapeutic and have no quality of life."

• Kim...
• Taken for less than 1 month
• August 17, 2019

For Type 2 Diabetes "So took my first dose of Trulicity yesterday. And it was, all in all, a pretty good day. Last night I woke up with abdominal pain and the worst nausea I have ever had in my 53 years of life. I have not held down anything today. And lucky me, I get 5 more days until it is out of my system. I will not take this ever again. I would not recommend this drug to anyone."

• Sav...
• May 21, 2023

For Type 2 Diabetes "My husband was in a bad car accident, and the pain and stress caused his blood sugar to be very high. After 3 months, he was prescribed Trulicity to get it to come down. Well, he had stomach pains, nausea, vomiting, and decreased appetite, and he lost 30 pounds in 2 months. He was NOT OBESE! Now he is weak and still can’t eat, even after quitting it 3 weeks ago."

• Bon...
• February 27, 2020

For Type 2 Diabetes "I took Trulicity for 5 weeks, and the 3 days after the first dose I was nauseous and somewhat constipated. Sugars came down somewhat, but the longer I took it, the worse I felt! Stopped taking it after the 5th week, and I’m still nauseated, and my abdomen hurts so bad! I’m praying this gets out of my system soon! I don’t have much of an appetite, which I’m glad for, but ready for the pain to leave!"

• Bon...
• February 27, 2020

For Type 2 Diabetes "I took Trulicity for 5 weeks, and the 3 days after the first dose I was nauseous and somewhat constipated. Sugars came down somewhat, but the longer I took it, the worse I felt! Stopped taking it after the 5th week, and I’m still nauseated, and my abdomen hurts so bad! I’m praying this gets out of my system soon! I don’t have much of an appetite, which I’m glad for, but ready for the pain to leave!"

• Edg...
• May 25, 2020

For Type 2 Diabetes "Been taking Trulicity for 4 years now with no side effect. 3 months ago, I started to feel bloated, stomach upset, keep burping, and nauseated every time I inject Trulicity. I am not sure if I will continue taking it as the side effect is starting to get to me. A1C is 7.8 with Trulicity."

• Di0...
• Taken for 1 to 6 months
• March 9, 2020

For Type 2 Diabetes "I took my first dose of Trulicity in January. I started having pain in my left side through to the back. The doctor suggested I take it every two weeks. The pain has persisted, plus now I am super nauseous and throwing violently. For the last four days, I’ve lived on fat-free broth. No more for me!"

• LCa...
• Taken for 1 to 6 months
• December 17, 2019

For Type 2 Diabetes "Diagnosed in October with type 2 diabetes, started Trulicity. Blood sugars normal. Developed back pain and fatigue. Injections on Fridays, day after Thanksgiving, diarrhea, nausea, burps like nasty sulfur x 4 days, very sick. To ER Dec 10th, chest pain, back pain, diarrhea, nausea. Labs normal for heart, pancreas, and liver. Thought severe flare of my GERD, saw PCM Thur 12th, increased Nexium, & more meds for stomach and diarrhea. Inject Friday 13th, sick again Sat & Sunday. No more Trulicity for me. Missed too much work and sick the past 3 weeks."

• Jea...
• Taken for less than 1 month
• December 24, 2020

For Type 2 Diabetes "I’m 73 years old, not overweight at all, and have had type two diabetes for the last 10 years. My A1C is up to 8.9, so my doctor started me on Trulicity. To say I am nauseous is an understatement. Headache, abdominal pain, absolutely no appetite. I don’t know how much longer I can tolerate this drug."

• Spr...
• April 30, 2020

For Type 2 Diabetes "This is my 2nd month on Trulicity. First month, I had the 1.75 and had too many side effects: nausea, stomach pain, loss of appetite, and some ankle swelling. Called doctor, and he reduced dosage to the .75, and so far, so good. I can’t take this med with Metformin, though, because I get a worse effect when I take both together."

• Wil...
• Taken for 1 to 6 months
• September 11, 2020

For Type 2 Diabetes "I have had type 2 diabetes for 16 years. Controlled well on a low-carb, high-fat eating plan (LCHF) diet. Got too difficult and gradually went back to a normal diet, but still low carbs. HBA1c was rising, so Dr. suggested Trulicity. I've had 5 injections and will see Dr. on Monday, this week. I've had enough, my levels have gone up even when combined with Metformin. I am getting side effects of feeling nauseous for about three days after the injection, burping, wind, constipated, no appetite. All thought of food makes me feel sick, the only good point is I lost 3 kgs. I can't continue, it's not suitable for me. If my readings had come down, maybe... a big maybe I'd continue. I've tried for just about 6 weeks, but I feel shaky, sick, constipated, it's not worth it for me."

• Jud...
• May 27, 2021

For Type 2 Diabetes "I have to say after reading these reviews, I was horrified and so scared because I took the injection before I read the reviews, and I am glad I did take it. The first day, I was very fatigued, the second day, I was good. I noticed I was a little nauseous, but not to where I was in pain or discomfort, and I also noticed I was not hungry at all, which caused my sugar to drop. I have had no other symptoms such as diarrhea or vomiting. Now, on the 5th day, I have felt very hungry and find myself snacking again. It's been now a week, and it did not cut my appetite like I wanted, but... my sugar levels are between 110 and 150 all day without insulin. I do check my sugars 3 times a day just to keep checking. I know it has only been one week, and I will update weekly just to see if anything changes. I have not lost 1 lb as of yet. I am just sharing my experience with anyone that may read the reviews and feel terrified of them like I did, everyone is different, so it will affect differently for every person."

• Lad...
• Taken for 6 months to 1 year
• September 22, 2016

For Type 2 Diabetes "I started on Trulicity in April of this year. At that time I weighed 352# and had been diagnosed as a new Type 2 diabetic. My PCP had tried a three-month course of Metformin and it dropped my 'number' a whopping 0.2. He recommended Trulicity and started me immediately on the 1.5 dosage, giving me the first injection in his office. From the first dose, I have had virtually no side effects. On occasion, I will get slightly sick to my stomach if I eat too much, or have a bout of diarrhea if I consume too many carbs, but that's it. This is mid-September and I have lost 57# without dieting or exercising or anything. Naturally, as the weight comes off, I feel more like moving around and doing things, but IMHO this is a miracle drug!"

• Hop...
• Taken for less than 1 month
• February 21, 2020

For Type 2 Diabetes "Just started Trulicity 3 days ago. The next day I started with gas pains, burping, and nausea. Today I have been drinking peppermint tea, and it has helped. The doc warned me about the side effects and said they would go away in a few weeks. My A1C was 11 consistently this past year. I needed to try something different. I am going to do my best to stick with it. If I can reach my goal weight and goal A1C, then it will be worth it. Hopefully."

• Sar...
• December 29, 2015

For Type 2 Diabetes "I have been on Trulicity for about 2 months now. It, along with diet and exercise, has helped me lose 12 pounds so far. I am only on the .75 dosage still. The first two days of taking this, I literally did not eat and forced myself to drink water. I just felt full, bloated, and slightly nauseous. I typically feel nauseous after the first couple of days after my Sunday injection, but it wears off. I'm not sure why people are so surprised at their loss of appetite, what do you think the commercials mean when they say 'while ____ is not intended for weight loss, it may help you lose weight'? MANY diabetic medications have this side effect, and for a reason I believe. Morning sugars are MUCH better, and I'm satisfied with Trulicity."