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Drospirenone / estradiol and Cramps: What Users Say

Brand names: Angeliq

Cramps: mentioned by 4 users (8.0%)

Based on user experiences from 50 Drospirenone / estradiol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 10.0%
weight gain 10.0%
cramps 8.0%
mood swings 8.0%
sore breasts 8.0%
sweating 8.0%
depression 6.0%
flushing 6.0%
spotting 6.0%

Reviews for Drospirenone / estradiol

Commonly mentioned side effects
  • Wea...
  • June 16, 2016

For Postmenopausal Symptoms "I've been on Angeliq for 6 weeks only. It has already helped with my mood swings and sweats, however, since the second week of taking it, I started spotting, and this has increased so much that it is soaking my clothing, and I ended up in the emergency room with severe bleeding, flooding. I've been told to keep on this for another week with tablets to help reduce the bleeding. These are not doing much. I notice that when I've taken a tablet of HRT, I then get cramping and then I flood. So, obviously not good. Anyone else had this?"

2 / 10
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35 Report
  • Gly...
  • November 11, 2016

For Postmenopausal Symptoms "I am 55 years old and went through menopause 2 years ago. I have still got my uterus, and after my yearly visit to my gynae, he decided to put me on Angeliq for my hot flushes. After taking them for 3 weeks and noticing absolutely no change, I started a period that lasted for 9 days (I haven't had a period in 2 years). After the bleeding stopped, I started with nausea and severe cramping. I phoned the gynae's office and was told it's normal and to carry on with the pills, but the cramping has got progressively worse, so I have stopped taking them. I am petrified to try anything else!!!"

1 / 10
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22 Report
  • Mar...
  • Taken for 5 to 10 years
  • September 26, 2021

For Postmenopausal Symptoms "Brain fog was causing me trouble at work to the point I feared I might lose my job. My doctor has had me on the bio-identical, very expensive medication for over 8 years. I have only good things to report. I responded within days by having a better overall feeling of being younger again and no or rare hot flashes. My hair is longer and thicker than ever before in my life - at 62, I am told I look 42. In a lot of ways, the hormone replacement stopped the clock, and if anything, my 'real age' reversed! My nails and skin are great and rarely a hot flash. My brain is happy and smart enough to handle complex work that I carry on joyfully. My doctor and I discussed the expense since the lower dose was the same cost. I split the pill and take a 1/2 or 1/4 and thus stretch it out over months. It is critical to take it daily, and as soon as you forget. I learned this because in trying to stretch it, I would skip days or just take it when I had a hot flash, and I began having ovarian pain."

10 / 10
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12 Report
  • Bee...
  • February 28, 2020

For Postmenopausal Symptoms "At 3 a.m. on the 2nd day of taking Angeliq, I started abdominal cramps, which got progressively worse. Stopped taking on the 5th day. Did some more research and figured I have endometriosis, which explained why I had debilitating pain every time I ovulated in my younger years. I'm 62 now. So the estrogen doesn't only invigorate the uterus and vagina, but also the bits of tissue that are sitting outside my uterus. They start paining because they start putting pressure on surrounding organs. My GP had to agree, even though Angeliq has the opposing progesterone. Rather going to treat symptoms of anxiety and irritability with an antidepressant. Need to boost serotonin levels for a while."

1 / 10
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5 Report

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