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Doxylamine / pyridoxine User Reviews & Ratings (Page 2)

Brand names: Diclegis, Bonjesta

Doxylamine / pyridoxine has an average rating of 7.3 out of 10 from a total of 165 reviews on Drugs.com. 63% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Doxylamine / pyridoxine

Commonly mentioned side effects
  • Bar...
  • January 18, 2017

For Nausea/Vomiting of Pregnancy "This is my 4th pregnancy. I've always had bad morning sickness with each pregnancy but always ended by my 10th week. I started the Rx at 7 weeks and tried stopping at 13 weeks but experience terrible withdrawal symptoms. I only take 1 pill at night. When I tried stopping the med, I violently threw up, nauseous all day, body aches, and excessive sweating. I would have never started the prescription if I knew stopping it was this painful."

3 / 10
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  • Cou...
  • Taken for 1 to 6 months
  • November 15, 2018

For Nausea/Vomiting of Pregnancy "Came into severe morning sickness at 6th week of my 1st pregnancy. Lost my appetite; nauseous all day, every day. Nights were the worst because I would wake up every 20 minutes, feeling like I needed to vomit. I lost weight. I tried homeopathic remedies. Nothing worked. I was so worried that I would have to live like this for my whole pregnancy. My doctor prescribed Bonjesta. Within 20 minutes of taking the first pill, I felt drowsy, but my nausea already started subsiding. I will take drowsiness over nausea any day. I have to work hard to stay focused, but still, I am able to work and function and eat. I highly recommend Bonjesta. I still experience mild nausea from time to time, but nothing like before. I take 1 pill when I wake up in the AM, plus 1 pill at approximately 6:30 pm."

9 / 10
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  • Cha...
  • August 12, 2016

For Nausea/Vomiting of Pregnancy "I was prescribed this medicine for my morning sickness. I haven't been able to get out of bed since I found out I was 6 weeks pregnant. This medicine does help me to not feel nauseous, but the side effects are terrible. I feel as if I've been given a heavy sedative. I started with the prescribed dose of two pills at bedtime. When I woke up the following day, I could barely lift my head off the pillow and was in and out of strange drug-induced sleep all day. I tried taking the medication again but only taking one pill. The effects were the same, and I felt like I was on heavy drugs. I tried for a third time but only a half pill. Same outcome. Can't get out of bed, foggy, and in and out of sleep."

1 / 10
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  • 2nd...
  • Taken for less than 1 month
  • August 24, 2014

For Nausea/Vomiting of Pregnancy "I'm 4 months along with my second child. This pregnancy is very different from the last. I never had such bad nausea, vomiting, and dry heaving. I'm taking this medicine on an as-needed basis. So far, I need one pill at night and another about mid-morning. The original prescription said one in the morning, one in the midday, and two at night. I did that once and slept until 2 pm the next day. That's not healthy either. The only complaint I have is the cost. It ran $178.53 for us. A cost that wasn't expected, but when Phenergan and Zofran aren't working.... you give in. Just as every OTC or prescription, there are side effects. For me, the benefit outweighs the risk. Try to stay away from medication until at least 13 weeks."

10 / 10
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  • Col...
  • August 3, 2015

For Nausea/Vomiting of Pregnancy "I lost 15 lbs due to nausea and vomiting since my 7th week of pregnancy. I was vehemently against taking any medication, but after I researched this medication, I felt that it was as safe as a medication can be during pregnancy. I was at risk of losing my baby due to the significant weight loss, so I am grateful for this safe, completely effective medication. It is working for me at the lowest dose, and I feel I should buy stock in the company selling this wonderful drug. I am able to eat, drink, and maintain a normal lifestyle after weeks of misery. I highly recommend this drug if the traditional methods of managing NVP are not effective for you. I was lucky enough to receive samples from my OBGYN, so I cannot say anything as to cost."

10 / 10
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  • Pre...
  • Taken for less than 1 month
  • January 20, 2021

For Nausea/Vomiting of Pregnancy "Well, I came to the comments hoping it wasn’t just me, haha! I started Bonjesta at 13 weeks, and honestly, I passed out the first night (can’t have nausea if you’re knocked out), so now I’m on day 4. It doesn’t put me out, but it’s like it amped it up. I’ve thrown up 3-4 times a day, and as soon as I put food on my tongue, I get gaggy and chills and end up not eating. I’ve been living on crackers and chips, then I throw those up. I tried a smoothie yesterday and ended up puking it all back up. Please tell me it’s almost over, lol."

5 / 10
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  • Raj...
  • Taken for 1 to 6 months
  • July 8, 2015

For Nausea/Vomiting of Pregnancy "I started taking Diclegis at 7 weeks (was totally against medicine, but the nausea was unbearable). I was so glad I did try it because it worked like magic. Huge difference the following day if I didn't take it at night. It also helped with my moodiness and oversensitivity to smell. 11 weeks later, I am discontinuing use of it - hoping I can manage the symptoms myself. I did not get side effects at first, but about 9-10 weeks into taking it (16-17 weeks of pregnancy), I started to lose sleep at night and stay tired all day. Since not taking Diclegis, I can sleep at night now. I think my body just got used to it and started to react with hyperactivity. Also noticed reduced fetal movement while taking it versus not."

9 / 10
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  • Ala...
  • Taken for 1 to 6 months
  • February 1, 2016

For Nausea/Vomiting of Pregnancy "I had morning sickness since I was 8 weeks pregnant. I had my first ObGyn visit at 12 weeks. In 4 weeks, I lost 11 lbs. :-( I felt miserable. I did not know there was medication to prevent nausea. My doctor prescribed Diclegis. I started 2 pills before sleeping, 1 pill in the morning, and another in the afternoon. It was magic and amazing. When I reached 20 weeks, I started feeling sick again, nauseous and dizzy, and shaking. I thought maybe I was doing overdose. I went down to 1 pill at night to sleep and I feel GREAT ALL DAY!!! Amazing... And I am currently 26 weeks and I still use it because I skipped one day and I felt horrible. Tip: if you skip or miss a pill at night, take one at any time and you will feel better. I love Diclegis."

10 / 10
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  • SSa...
  • Taken for 1 to 6 months
  • May 3, 2020

For Nausea/Vomiting of Pregnancy "When I was around 6 weeks pregnant, I was vomiting NONSTOP. It got to the point where I could not even hold down water. The doctor prescribed me Diclegis, and it has been a MIRACLE drug. I take two tablets at night before I go to bed (caution that it does make you very sleepy), which I find an added perk because it helps me get a full night's rest. There are some mornings where I wake up still feeling slightly nauseous, but I am not vomiting, so the occasional slight nausea I can deal with. If you’re looking for something to make the 1st trimester nausea/vomiting disappear (or almost disappear), look no further because this is the drug for you."

10 / 10
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  • meg...
  • January 2, 2016

For Nausea/Vomiting of Pregnancy "This is my first pregnancy and have been in the hospital twice, and I'm only 8 weeks. I have never been so sick in my entire life, one day I vomited for 16 hours every 15 minutes. Finally, this was prescribed to me, and I started the night I was discharged, and I have not even felt sick one bit. I was doing over-the-counter B6 and Unisom, but it did not seem to work for some reason. This pill is amazing, and I would recommend it to anyone else who is suffering as badly as I did."

10 / 10
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  • Lyn...
  • September 8, 2015

For Nausea/Vomiting of Pregnancy "I have been so sick since becoming pregnant, vomiting several times per day. Initially, I was given Zofran, but the minute it would wear off, I'd start vomiting again. My doctor switched me to Diclegis a few days ago and I feel great! No vomiting, no nausea, and I'm not worried about the potential problems that extended use of Zofran could cause anymore."

10 / 10
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  • Bec...
  • Taken for 1 to 6 months
  • January 23, 2020

For Nausea/Vomiting of Pregnancy "I had pretty bad morning sickness starting around my 6th week of pregnancy. I got to where I dreaded waking up the next day because I knew I’d be super nauseous and sometimes vomit. At my first appointment at 8 weeks, I told the doctor I was experiencing nausea and vomiting, and he prescribed me this, and it’s an absolute godsend! Taken at bedtime, I felt much better the next day! You don’t have to worry about this drug because all it is is a high dosage of Vitamin B6 and Unisom. I’m now 27 weeks and still taking it every night because I’ve been feeling good and am scared to stop it and be sick again! Lol. I tried stopping it early in the 2nd trimester but promptly vomited throughout the day, so I plan on continuing to take it because my doctor said it is safe to do so."

10 / 10
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  • SJa...
  • Taken for less than 1 month
  • September 3, 2018

For Nausea/Vomiting of Pregnancy "Was extremely nauseous and was put on Zofran. Still had nausea, so my doctor suggested I try Bonjesta. So far, it has made my nausea manageable and even nonexistent at times. I have gained the weight back that I had lost from not being able to eat. The worst part is the tired feeling, but I will take that over the intense nausea any day. It does make my heart pound, but nothing that wasn’t already listed in side effects."

10 / 10
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  • Fir...
  • Taken for less than 1 month
  • July 16, 2015

For Nausea/Vomiting of Pregnancy "I have been taking Diclegis for 2 weeks now, and I feel amazing. Taking 3 pills a day seems to be the magic dose for me. I previously tried Zofran, which helped minimally, but I was still nauseous and vomiting violently a few times throughout the day. I work full time, so I really needed something more effective, so my doctor recommended I try Diclegis. Two thumbs up, just a little pricey."

9 / 10
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  • Pau...
  • March 23, 2017

For Nausea/Vomiting of Pregnancy "This was the only medication that helped me deal with morning sickness, that actually it was never just in the morning. I was sick all day and all night. It makes you sleepy, but it's not like you can't get out of bed. They tell you to take 2 before bed, another one in the morning, and one more at noon, but I'm just taking one before bedtime and one in the morning so I don't feel super sleepy, and it works perfectly for me! No more sickness, and I can eat anything I want :) Plus, it's super safe for the baby!"

10 / 10
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  • Hum...
  • August 5, 2020

For Nausea/Vomiting of Pregnancy "So, the first time I took Diclegis, I was around 8 weeks pregnant, and it worked wonders. I couldn’t relate to negative feedback here, but now with my second pregnancy, it doesn’t work like the first time. I still throw up, I’m still nauseous, I hate the smell and sight of food, but I’m not going to say I’m as miserable as I was with my first pregnancy without this drug. Maybe because I’ve been here before, I know what to eat and what to avoid, or maybe it’s Diclegis working 20 percent only. I hate to say this, but ladies, it doesn’t work every time."

3 / 10
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  • Dan...
  • Taken for 1 to 6 months
  • September 19, 2021

For Nausea/Vomiting of Pregnancy "10/10 I've had terrible nausea and vomiting since week 6, currently in week 11. Two nights ago, I forgot my pill ONE night, and the next AM, projectile vomiting. What does this tell me? This WORKS, and I will make sure I don't miss another dose as I feel great when I do take it."

10 / 10
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  • KT1...
  • Taken for less than 1 month
  • February 1, 2020

For Nausea/Vomiting of Pregnancy "I was experiencing pregnancy nausea without vomiting from week 6 to current (week 8). I wasn’t able to eat, really only able to rest in bed for the most part. I tried Bonjesta, and it’s helped a great deal. I still experience slight nausea, but it’s bearable, and every so often I will actually feel hungry and am able to eat like normal. I have tried Zofran as well, which does help with nausea but backs you up badly, so be careful."

10 / 10
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  • Mom...
  • Taken for less than 1 month
  • July 14, 2019

For Nausea/Vomiting of Pregnancy "With my first daughter 5 years ago, I had pretty bad nausea but managed to get through it without needing any medication. This time around was a completely different story. I really tried to not take any medicine, but after two days of being unable to consume any food, it was time (I was 6 weeks). My doctor prescribed me Bonjesta and warned me it would make me tired. Boy, was she right! I took this the first night around 9 pm, woke up the next day, and within 2 hours, I had to lay back down for a 3-hour nap. The nausea has mostly gone away, but tonight it came back. I haven’t been taking it twice a day yet as I’m afraid I’ll be a zombie, but I think I might need to. Works great for the morning sickness, but I just wish it didn’t make me so tired! Also, this is expensive. My insurance covered $600+, but I still had to pay about $135 out of pocket."

8 / 10
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  • Ste...
  • Taken for less than 1 month
  • January 6, 2017

For Nausea/Vomiting of Pregnancy "The first time I took it, I took one pill upon waking up. I literally stayed in bed the entire day. I could hardly open my eyes, let alone lift my head off the pillow. Thank goodness it was a weekend, and I didn't have to work! I chalked it up to a bad morning sickness day and took two at bedtime that night. The next morning, it wasn't quite as bad, but it was still a struggle to get through the day. I wasn't nauseous, but I was so fatigued and sleepy, and just felt 'bad.' I realized it might be the Diclegis, so I didn't take any more after that. So now I'm back to all-day nausea (no vomiting), but at least I can function! I only recommend Diclegis if you've got major vomiting/HG. Otherwise, the side effects just aren't worth it."

2 / 10
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  • SBi...
  • Taken for less than 1 month
  • June 22, 2019

For Nausea/Vomiting of Pregnancy "I’m 10 weeks pregnant and started getting nausea at 6 weeks. I was prescribed Zofran initially, and that didn’t really help. Now on Bonjesta, and it’s an improvement. I do have to take it morning and evening, but it helps keep the nausea under control and sometimes takes it away completely. It’s still a bit of a struggle because it does make you more tired, but I’ll take it. Anything but this nausea, please."

8 / 10
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  • kim...
  • August 23, 2015

For Nausea/Vomiting of Pregnancy "This medication works wonders! I can take it without having to eat something before, which was so helpful, considering I couldn't hold any food down! I lost more than 20 lbs due to vomiting and nausea. And getting into a moving vehicle was the worst! I take one in the morning and I feel good all day! I love it so much, lifesaver."

10 / 10
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  • Kat...
  • June 9, 2018

For Nausea/Vomiting of Pregnancy "I know this doesn’t work for everyone, but before I started it, I was praying for twins because I didn’t think I could take another pregnancy. Since I started it, my whole experience has been completely different, and I feel amazing! Worth every penny!!"

10 / 10
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  • Fre...
  • August 24, 2017

For Nausea/Vomiting "This medication gave me my life back. I started it yesterday, and I do not need any more time to try it out to review it. I was throwing up so much that I had thoughts of suicide and/or termination of pregnancy... and we planned for this baby. Anyone who knows me knows those thoughts are insane for me, but I couldn't take another day of laying in bed throwing up. I was expecting to fall asleep and not wake up based on the comments, but I woke up completely fine at 6 a.m., and I took 2 pills before bed at 10 p.m. I was pretty tired until 11 a.m., but I will take tired ANY DAY over being sick and nauseous. I could sleep like crazy right now, but I will not stop taking these meds. It was $894 before insurance for 120 pills, and my copay was only $40!!!!"

10 / 10
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  • Jsi...
  • April 23, 2016

For Nausea/Vomiting of Pregnancy "I have been feeling pretty nauseous all day (first trimester of pregnancy), and my healthcare provider gave me a sample of this drug to try. I wanted to share my experience, as all I've read are glowing reviews. Glad it's working for some people, but I have to imagine there are others who experienced something similar to me. I have taken it now for 3-4 days, which should have been enough time to get a feel for whether or not it works. It did absolutely nothing for my nausea. If anything, it made me feel worse. I was so tired I couldn't function. Had to lay down in the middle of the day for a few hours, feeling so tired and sick. I didn't take any last night, and today I feel better than I have since I started taking it!"

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.