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Doxycycline and Vomiting: What Users Say (Page 4)

Brand names: Vibramycin, Monodox, Adoxa, Doryx, Oracea, Doxy 100, Avidoxy, Acticlate, Doryx MPC, Doxy-Caps, Targadox, Morgidox, LymePak, Mondoxyne NL, Doxy-D, Oraxyl, Alodox, Adoxa Pak, Adoxa TT, Adoxa CK, Uracil Okebo Doxy 200 …show all brand names

Reviews for Doxycycline

Commonly mentioned side effects
  • Pai...
  • Taken for less than 1 month
  • January 10, 2023

For Chlamydia Infection "I was diagnosed with a chlamydia infection and prescribed doxycycline 100 mg tablets for 7 days. I am hoping the pain goes away as it hurts to pee. I have one more pill. I have to eat before taking this medication as it did cause me to vomit one time after 2 hours of taking it."

5 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • January 23, 2014

For Acne "I'm a 22-year-old female who has struggled with acne since I was 11. I have been on doxycycline (100 mg/day) for the past few years but have struggled with taking it as prescribed (daily) because of the severity of the nausea/vomiting that would cause me to miss school. I talked to my dermatologist, and she prescribed me a coated tablet, which was significantly easier to digest. Downside: the coated tablet was much more expensive, even with good insurance. With the coated tablet, I notice no negative side effects. This medication works fast. As soon as I would begin taking it for 5-7 days straight, I would notice a difference in my face, fewer new breakouts. As soon as I stopped, however, the breakouts would begin to slowly appear again."

8 / 10
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  • Glo...
  • May 16, 2018

For Skin or Soft Tissue Infection "I was prescribed this medicine for a skin infection caused by MRSA. Yesterday was my 4th day of taking the capsule, and within minutes, I was retching my guts out. I am a cancer survivor, and even with aggressive chemo, I never threw up! I also experienced extreme loud ringing in my ears for several minutes. And I notice that I feel very tired on this drug. Well, that's enough for me... I'm out!!!"

2 / 10
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Frequently asked questions

  • Jus...
  • September 6, 2017

For Acne "I had mild cystic acne and have been on this medication for almost 2 months and am pleased with the results. I do believe, like with most acne medications, that it brings the acne to the surface and makes it worse before it becomes better. The doctor suggested taking the medication on an empty stomach. When I would do so in the morning, it would make me extremely nauseous. So I started taking it at night right before I go to bed, and it has been much, much better. For those that have said it made them nauseous or vomit, I'd recommend taking it early evening with food and a really large glass of water (it really burns if it gets stuck in your throat). Even when I've had difficulty sleeping (unrelated to the medication), I never felt nauseous. My doctor said to use it for 2 months and then go back and see him."

9 / 10
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  • amy...
  • Taken for less than 1 month
  • May 21, 2015

For Acne "I've had acne for a long time, all my teen years into adulthood. I'm 29 now and finally asked my doctor to prescribe something. I'm about 3 weeks into taking doxycycline, and I had noticed slight improvement until a few days ago. I just got my period, and dear God, my acne is more cystic and crazy than ever! It's mainly on my cheeks and chin now (which seems to be what others have experienced on this medication), and they are large, painful, and ugly. Ugh. I'm truly hoping this is the whole 'getting worse before it gets better' thing. I'm gonna stick with it and hope that this is just a one-time thing. I also began using the Acne Free Severe system with this med, so we shall see. Oh, and the first day I took the med, I vomited. Must eat prior!"

5 / 10
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  • SCa...
  • May 25, 2017

For Acne "I have moderate to almost severe acne. I have been on doxycycline for almost 4 months now, and my skin has improved drastically. At the first part of taking the medication, I started purging real bad that I dread leaving the house every time. Have some patience with this medication because it only took effect for me in the 3rd month. I'm only left with all the acne scarring now, very occasional pimples popping out and breaking out when it's about to be the time of my month! This is my third time trying out this antibiotic, as the first two times I never had the determination to continue the entire phase. Make sure your derm is lowering your dosage along the journey because I heard it helps a lot in avoiding horrible breakouts after stopping the med."

7 / 10
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  • Mic...
  • Taken for less than 1 month
  • October 1, 2021

For Bacterial Infection "Not the drug for me. First time I took it for a suspected infection, and it made me feel so sick I was bedridden for over a week. About 5 days in, and I couldn't stop vomiting. 10 years later, I was prescribed it for a possible infection that I had no symptoms of. 3 days in, and I could barely get out of bed, and when I forced myself to get up, I passed out within the hour with a weird head pressure. Great drug for those it helps, but intolerable for me."

1 / 10
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More FAQ

  • sel...
  • Taken for 1 to 6 months
  • March 29, 2017

For Acne "Coming up on 2 months on this 100 mg twice a day. Take on a full stomach. It makes me throw up if I haven't eaten food with it. My skin has progressively gotten worse. I don't think it is because of the doxycycline, I think my body just wants to continue down the path of giving me acne. I am on it for moderate cystic acne and I am still getting cysts regularly and am now breaking out on my forehead, whereas before it was just on the jawline. Not sure when this is supposed to work, but I look pretty darn bad. Will finish the treatment and hope for the best :("

2 / 10
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  • suz...
  • October 12, 2009

Doxycycline for Acne "Adoxa worked quite well in conjunction with being on Yaz (which makes the Yaz useless as actual birth control). It really cleared up my lifelong battle of breakouts. However, there were some side effects that went along with the long-term use of the antibiotic as strong as doxycycline, like the nausea and vomiting. It was well worth it. I never had a breakout while I was on it for 6 months. After my treatment was completed, the Yaz helped with the maintenance for a while. Every once in a while, I get a small pimple. Nothing compared to the big, icky ones I used to get."

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • December 20, 2012

For Bacterial Infection "Have a cold-related earache. Took 200 mg in the morning with coffee. Nausea within five minutes, vomited within ten minutes. No other malaise. Never a problem with tetracycline but am allergic to penicillin (identical reaction). This was my first dose."

2 / 10
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  • Anonymous
  • November 21, 2009

Doxycycline for Acne "I'm 14 years old, and my dermatologist prescribed Doryx for me for 2 months, and all it did was create worse acne. I have no idea why it didn't work, but I was put on Sulfamethoxazole about a week ago, and I already see a difference. My dermatologist said this drug is almost the same as Doryx, but has a different molecule in it. If you are going to try Doryx, I would definitely take it with food. With Doryx, I threw up 4 times because I didn't take it with enough food."

1 / 10
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  • Tir...
  • Taken for 1 to 6 months
  • September 27, 2020

For Lyme Disease "I was on doxy three times within 8 weeks. Each time, I was prescribed 100 mg 2x a day. The first time was 21 days for Lyme disease and shingles at the same time, things were okay, just a little dizzy. After being off it a week, the second time was 7 days for a cellulitis infection, I felt queasy and dizzy with it that time. The third time was about a week later after a small hand surgery. After 1 1/2 days, I was so sick, I had nausea, dizziness, and vomiting. I threw the doxy away. I believe my body was done with taking so much of it in a close time frame."

5 / 10
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  • Lov...
  • March 23, 2017

For Pneumonia "Was prescribed doxycycline Hyclate. The first day I took it as prescribed, no food. Made me feel sicker, vomited, felt tired, had to lay down for 1 hour. I did this a second day, then said, well let me try it with something light on my stomach (cracker, soup, or half a piece of wheat bread). Did this for 3 days, felt worse and worse, started losing my appetite. Fatigue was at a high, cough was terrible to where each cough I was urinating a bit. I just felt bad. My family took me back to the ER, doctor checked me. She said it sounded like it was clearing up, didn't want to do another X-ray due to too much radiation. Changed my meds to azithromycin 250. Started today taking 2 tablets 1st day, then 1 tablet each day 'til gone. I feel good, and I took on an empty stomach."

4 / 10
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  • Sen...
  • July 23, 2013

For Acne "I've always had mild teenage acne since middle school, and nothing worked. I finally decided to go to the dermatologist to get rid of my acne once and for all. Once I got the prescription, I was told to avoid dairy. I was so nauseous every day, throwing up at school for a week straight. But other than extreme nausea and occasional vomiting, within 2 months of diligent pill taking, 95% of all my facial, shoulder, chest, back, and cystic acne has cleared. Other than take with food and dairy, or prepare for some side effects, this has worked wonders. Highly recommend."

8 / 10
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  • Umm...
  • Taken for less than 1 month
  • December 18, 2020

For Chlamydia Infection "I've been taking doxycycline for 5 days, and I feel terrible. When I started taking it, I had barely any symptoms. My discharges smelled a little bit bad, but in the past five days, it has gotten way worse. I also puked in the morning and felt nauseous the whole day. I'm kind of scared that it won't work because I puked 10 minutes after taking one of the pills."

7 / 10
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  • Anonymous
  • December 18, 2010

For Bacterial Infection "I was put on doxycycline because I had a sinus infection that I just couldn't fight off. I tried taking it for three days but had excessive, explosive vomiting about a half hour after I took it. I was switched to another antibiotic, but I couldn't take it long enough to help."

1 / 10
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  • Nic...
  • Taken for less than 1 month
  • October 17, 2019

For Acne "Just a little update from my previous review about this drug. So I'm coming to the end of my first month on this drug, and so far it's been awful. I have had a purge about 50 times before, so I know one when I see one, but after around 12 days of my acne staying the same, it's now breaking out in places I haven't had spots in for years... and doesn't seem to be a purge and cleaning. I think personally the doxy has just become ineffective after the 12 days, so it's just doing nothing but causing it. So far, my eyes have been too sensitive to drive, I have thrown up almost twice every week, constantly feel dizzy and weak, and I don't see why I should continue it. Giving it another week, then I'm stopping it and demanding Accutane. Unless your acne is really mild, I wouldn't even bother using this, as it won't do anything. The only drug that's actually proven to work is Accutane."

2 / 10
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  • Soa...
  • Taken for less than 1 month
  • October 4, 2019

For Skin or Soft Tissue Infection "I was prescribed this after my other antibiotics didn’t fully clear my sinus infection. Because of my first antibiotic, I ended up getting fluid in my ear, causing vertigo and was prescribed this. Every time I take this, I instantly feel like vomiting. I have taken it with and without food and still feel horrible nausea and vomiting right after. After I vomit, I feel fine. This is the only antibiotics I have taken that makes me vomit, though it is one of the most common side effects. I can’t wait to get done with this round of antibiotics and hopefully it clears up my ear."

4 / 10
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  • Anonymous
  • December 31, 2010

For Acne "I was given this medicine to clear up my acne, and it has worked so well. For those who say they got stomach aches or had vomiting, it is probably due to the fact that they didn't eat a whole meal before taking it. Because it happened to me once, and I learned my lesson after that. So don't forget, EAT when taking!"

9 / 10
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  • Cup...
  • May 11, 2016

For Acne "I've been on doxy for about 3 weeks straight now. My skin isn't getting any worse, but it's not getting any better either. It also makes me so nauseous, and I throw up sometimes. It doesn't seem worth it to me right now for the medication to be doing nothing except making me sick."

6 / 10
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  • Hat...
  • Taken for less than 1 month
  • March 28, 2016

For Chlamydia Infection "I've been taking this antibiotic for a few days now. And just wondering if I'm totally screwed. I took my first dose. Made me vomit, so I stopped taking it for a day or two. Then started taking it again with food, which helped. But because I missed doses, I don't know if it will still keep working. I have to take two a day for fourteen days."

5 / 10
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  • Ire...
  • Taken for 1 to 6 months
  • November 14, 2018

For Acne "I used this for about 1 month and a week, so 38 days. And it gave me a horrible itchy rash as a side effect. Not only that, I would sometimes get an upset stomach, especially if I did not eat before taking the pill. I got off it barely 2 days ago due to this rash I’ve never had before. I also threw up once for not eating before the pill, and all these side effects it gives you are not worth it. I would definitely not recommend taking this pill."

1 / 10
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  • Ano...
  • Taken for less than 1 month
  • August 12, 2021

For Chlamydia Infection "These meds will definitely put you down if you don’t take this seriously! I have a very weak stomach and have tried doxycycline twice now. This is my third time on it, and I can honestly say that eating carbs for the morning pill has saved me. I’m on day 4 and already feel immensely better, with the symptoms slowly diminishing. I know this medicine tells you it’s best on an empty stomach, but the past two times taking this pill, I've thrown up at least one pill in the morning from not eating, and it didn’t work. I even went to the pharmacy to get another pill to add it onto my week, but it still wasn’t enough. You need to take all your medicine in the same time frames, evenly spread out (12 hours). I promise you, potatoes, bread, tater tots, or even McDonald’s french fries! Whether you have to take this for a week or more, know you’re gonna get through this and feel 100 times better. Hoping I get through these last couple of days and the test comes back negative."

6 / 10
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  • New...
  • Taken for less than 1 month
  • February 7, 2021

For Bronchitis "While I normally never have reactions to a new medication, this one I did. Half an hour after taking it, I had diarrhea and vomiting. Prescribed for bronchitis. 100 mg. The first dose was without food. I'll try the second dose with food and see how that goes."

4 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • August 17, 2021

For Bacterial Infection "I would never take this medication ever again, unless it was life threatening. There are many other antibiotics; it doesn't have to be this one for my case. I'll elaborate: I received the medication for acne, which isn't very 'life threatening.' The side effects I got were vomiting, diarrhea, and esophagitis. Additionally, I decided to stop taking the medication after the esophagitis, which made it extremely painful to swallow and lay down. I wish my doctor had discussed the side effects of this medicine with me; if I knew then, I would have taken something else."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.