Skip to main content

Doxycycline for Rheumatoid Arthritis User Reviews

Brand names: Vibramycin, Monodox, Adoxa, Doryx, Oracea, Doxy 100, Avidoxy, Acticlate, Doryx MPC, Doxy-Caps, Targadox, Morgidox, LymePak, Mondoxyne NL, Doxy-D, Oraxyl, Alodox, Adoxa Pak, Adoxa TT, Adoxa CK, Uracil Okebo Doxy 200 …show all brand names

Rating: 8.0

Doxycycline has an average rating of 8.0 out of 10 from a total of 5 reviews for the off-label treatment of rheumatoid arthritis. 80% of reviewers reported a positive experience, while 20% reported a negative experience.

10
40%
9
20%
8
20%
7
0%
6
0%
5
0%
4
0%
3
20%
2
0%
1
0%
  • TVL...
  • December 13, 2019

"20 years ago (1998) my wife got a flu shot, which was contaminated with mycoplasma bacteria. The result was Psoriatic arthritis. She was treated with Remicade, a popular biologic, and methotrexate. In 2008, we were made aware of the fact that arthritis is a bacterial infection, not an 'autoimmune' disease. We found an ethical Rheumatologist who put my wife on Doxycycline 50mg daily. She saw results in 6 months and was off Remicade. She still took the poison methotrexate for 10 more years until it started causing liver cirrhosis. When she stopped that and with NAC (N-acetylcysteine) and milk thistle, she overcame the cirrhosis. The fact is 'autoimmune diseases' are usually a bacterial infection which can be cured, not just treated for the symptoms. The ethical doctor is now trying to get her off the Doxycycline, which means she is cured of the mycoplasma bacteria."

10 / 10
Was this helpful?YesNo
76 Report
  • Dan...
  • December 30, 2017

"I have aggressive RA and was put on doxycycline by a doctor and was supposed to take an uptake inhibitor and prednisone at the same time. After reading negative comments about prednisone, I decided to take doxycycline alone. Within 3 days, I started to get some relief, and by 6 days, it was much more. My next appointment with the doctor was at 7 days, but I was not able to get there. I split pills in half to last until the appointment. When I told the doctor I felt much better from doxycycline, he said there was no evidence suggesting it is helpful. I had already done research online and knew this was not true. I found a source that gave me doxycycline. Roadback.org suggested 3 times a week, 100 mg, Monday, Wednesday, and Friday. I'm still hanging in there."

10 / 10
Was this helpful?YesNo
65 Report
  • Pae...
  • May 6, 2016

"For me, this drug has helped when others have failed me. I started Simponi, and it worked great for months until I developed a severe allergic reaction to it for some reason. Then everything I tried after, similar to Simponi, I became allergic to in some way. Finally, I found an article online that talked about the use of antibiotics to treat RA. That is when I asked my doctor about trying doxycycline. She once took me off of it and tried minocycline, which did not work for me, in fact, it made me worse. Please never try this. Then she took me off of everything, I got worse again, until finally putting me back on the doxycycline recently, and I am slowly getting better again."

8 / 10
Was this helpful?YesNo
42 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • July 21, 2020

"I have suffered from severe inflammatory arthritis for 10 years. I have it in over 40 joints. I was on prednisone for 3 years that gave me cataracts and DMARDs, including Humira and methotrexate. I am considered to have refractory arthritis, meaning I don’t respond well to multiple treatments. I struggle with regular respiratory illnesses as a result of immunosuppression. I recently was prescribed doxycycline and began to feel considerably better. Dr. Brown might have a point!"

9 / 10
Was this helpful?YesNo
23 Report
  • LDL...
  • August 24, 2017

"WOW! I have tried biologics, methotrexate, TNF blockers, and Prednisone to treat severe RA and basically concluded nothing treats this evil monster. Then, I tried doxycycline, and WOW. The agonizing constant pain and fatigue subsided within the first week. 200 mg a day for the next 90 days until my rheumatologist appointment. I could hardly wait to share the great news!! I felt normal for the first time in 4 1/2 years!! Then, 35 days in, things took a sudden turn. I started getting skin tears, which is a common occurrence in the elderly. I am 50. My skin tone changed and appeared see-through, opaque. When I ran my finger down my arm, it instantly left a bruise. Suddenly, I had pus bumps all up my arms and the back of my legs. Goodbye, Doxy."

3 / 10
Was this helpful?YesNo
23 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Rheumatoid Arthritis

Care guides

Symptoms and treatments

Medicine.com guides (external)