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ZzzQuil and Restless Leg Syndrome: What Users Say

Restless leg syndrome: mentioned by 6 users (8.8%)

Based on user experiences from 68 ZzzQuil reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

restless leg syndrome 8.8%
headaches 7.4%
insomnia 5.9%
restlessness 5.9%
anxiety 4.4%
increased heart rate 4.4%
tiredness 4.4%

Reviews for ZzzQuil

Showing 6 reviews tagged with "restless leg syndrome". Clear filters to view all 68 reviews.
Commonly mentioned side effects
  • Fel...
  • August 25, 2019

For Insomnia "I used to work overnight, so now I suffer from being on an opposite schedule. Up at night and sleeping during the day. I decided to take ZzzQuil, and it kept me up all night. The first time I took it, I didn’t sleep soundly and had crazy dreams. The second time, I suffered from a little restless leg syndrome, but I thought maybe it’s okay since I have arthritis as well. I tried it one more time, and it was awful. I tossed and turned all night. My legs were so restless every time I started to fall asleep, my legs woke me up because I was so uncomfortable. I’m totally throwing it away. I even couldn’t sleep the next day, and I was exhausted. It was horrible."

1 / 10
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47 Report
  • Dre...
  • Taken for less than 1 month
  • September 30, 2022

For Insomnia "Trying to get off an enormous amount of THC full CBD, which helps sleep a bit but makes me wonky. So, ZzzQuil. Unbelievably awful, an experience I hope nobody would have. Didn't make me sleepy at all, but the restless legs were absolute torture. Torture. This side effect is not admitted by the manufacturer, but it's so real it's scary."

1 / 10
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12 Report
  • Nev...
  • February 3, 2023

For Insomnia "Tried this for the first time, and never again. I had the worst case of anxiety and restless leg syndrome that I’ve ever experienced in my life. Woke up tired from being up more than if I didn’t take it. On top of that, horrible dreams as well."

1 / 10
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3 Report

Frequently asked questions

  • dco...
  • Taken for less than 1 month
  • March 24, 2020

For Insomnia "Diphenhydramine triggers restless leg syndrome."

1 / 10
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10 Report
  • Mar...
  • Taken for less than 1 month
  • April 10, 2020

For Insomnia "ZzzQuil. It's really not working. Took it for the first time and could not sleep because of increased restless legs symptoms. Waste of money."

1 / 10
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8 Report
  • Che...
  • Taken for less than 1 month
  • April 5, 2023

For Insomnia "Tastes funny. Gave me a headache and restless legs, as well as twitching. Doesn’t help me doze off any better than not taking it."

1 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.