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Diclofenac / misoprostol and Upset Stomach: What Users Say

Brand names: Arthrotec

Upset stomach: mentioned by 7 users (12.5%)

Based on user experiences from 56 Diclofenac / misoprostol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

upset stomach 12.5%
gas 7.1%
nausea 7.1%
bloating 5.4%
dizziness 5.4%
increased appetite 5.4%
stomach pain 5.4%

Reviews for Diclofenac / misoprostol

Commonly mentioned side effects
  • Jud...
  • Taken for less than 1 month
  • February 21, 2013

Diclofenac / misoprostol for Rheumatoid Arthritis "I have been living with four swollen fingers on my right hand (my dominant hand) and have trouble sleeping with pain in both hips and shoulders. At 49, I feel far too young for arthritis, but sometimes life is not fair. The doctor prescribed Arthrotec yesterday. Two pills in, and I can hold a pen, type, and slept like a baby last night! I'll take the queasy stomach and gas if it means I'm not cranky because of poor sleep and constant pain!"

9 / 10
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69 Report
  • Dav...
  • October 1, 2015

Diclofenac / misoprostol for Rheumatoid Arthritis "I recently switched from Celebrex to Arthrotec. Although my stomach has been very upset most days, the pain in my shoulders, hips, and knee has been greatly reduced. Also, I have gained considerable mobility in the range of motion in my leg/knee."

8 / 10
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32 Report
  • Anonymous
  • Taken for less than 1 month
  • August 3, 2014

For Osteoarthritis "I was prescribed 50-0.2 mg twice a day. This medicine did work to relieve my back pain, but it came at a cost. It caused me to have severe stomach cramps and constantly feel nauseous. I had to stop taking the medicine because of this problem."

6 / 10
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25 Report
  • 11Q...
  • May 26, 2018

Diclofenac / misoprostol for Rheumatoid Arthritis "Suffering from RA, osteo, fibro, and Sjögren's. Diagnosed at 41, am now 53. On Enbrel and Arthrotec 75. This combination works very well for me, I still have pain, but it is manageable. I tried to do generic Arthrotec, but it did not work. I usually take one tab before bed. If I am going to be very active, I will take one in the morning as well, but that is rare. The gas and stomach upset are expected, along with feeling very hungry, and I do have bathroom issues from it. I have lost weight while taking this. I believe a lot of inflammation stems from the digestive tract, and when it is emptied, I suffer a lot less. I will watch my kidneys, but as for this med, I love it, and the pros outweigh the cons."

10 / 10
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10 Report
  • 06H...
  • June 2, 2017

Diclofenac / misoprostol for Sciatica "Started taking this medication about a week ago for sciatica-related pain. I had L5-L6 back surgery 10 years ago and get flare-ups of pain from post-surgery. It has helped the pain a fair bit. I still feel the right buttock pain when driving my car, but other types of sitting are much better. The side effects are not so good: a lot of bloating. I feel like I have a balloon in my tummy, upset stomach, lightheadedness, and dizziness. With having vertigo in the past, it's hard to tell if it's vertigo or the medication. The doctor wanted me to try it for 2 weeks, but I will go see him today after 1 week and have a chat with him about it. My dosage is 2 pills per day with food, 50MG. I will ask if taking 1 per day may be a good idea, and who knows, it may be enough."

7 / 10
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13 Report

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  • Lau...
  • Taken for less than 1 month
  • April 8, 2018

Diclofenac / misoprostol for Osteoarthritis "After taking two 50 mg doses am and pm, I am having to sit up in bed, hoping that the gas and stomach upset will pass so I can get some sleep. I did notice some pain relief, but I won't take it again due to the stomach upset."

3 / 10
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9 Report
  • Her...
  • Taken for 10 years or more
  • December 12, 2012

Diclofenac / misoprostol for Rheumatoid Arthritis "I have been taking this for 12 yrs, made a big difference in my life. Tried every medicine, and none had the same effect. Take two pills a day, 3 upsets my stomach. Without this, I would be bedridden."

10 / 10
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51 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.