Diclofenac / misoprostol User Reviews & Ratings (Page 2)
Brand names: Arthrotec
Diclofenac / misoprostol has an average rating of 8.2 out of 10 from a total of 56 reviews on Drugs.com. 75% of reviewers reported a positive experience, while 7% reported a negative experience.
Reviews for Diclofenac / misoprostol
- EDW...
- Taken for 10 years or more
- November 11, 2012
Diclofenac / misoprostol "I have been on Arthrotec for 12 years now. For me, it was a lifesaver. I fractured 11 vertebrae, both shoulders, both legs, both arms - and had multiple surgeries. This medicine was like no other I had tried before. It allowed me to regain some type of life."
- cal...
- June 27, 2009
Diclofenac / misoprostol for Rheumatoid Arthritis "I was on Arthrotec for about 2 years and found it to be a great drug, but now have had to go off it because of the risk of kidney damage and cannot take any more NSAIDs. I have been put on Plaquenil, and while waiting for it to kick in, have also been put on Prednisone, which has helped tremendously. Hope the Plaquenil will soon work so I can get off the Prednisone."
- Rob...
- Taken for 10 years or more
- July 30, 2020
Diclofenac / misoprostol for Osteoarthritis "I have had problems with my back for decades. Now, at 73, the challenges are worse. The family doctor says my whole back is degenerating (arthritis and compressed discs primarily). I have used Arthrotec in the past (at 50 mg or 75 mg). I got away from it when I developed chronic kidney disease. My family doctor has me on Tylenol Arthritis (the maximum amount I can take). I've been taking that for a while, but now I'm getting breakthrough pain. My kidney specialist said Arthrotec would be ideal for breakthrough, but no more than one tablet a day. It all works. I am very happy with the results."
- Val...
- Taken for less than 1 month
- September 30, 2015
For Osteoarthritis "Tried several anti-inflammatory drugs with 0 pain relief. I was ready to try cortisone shots in my painful, crippling hips (both) till my Dr said, let me try this last pill for you with immediate pain relief! I cried and felt like giving my Dr a big, tearful hug! Wow... what a difference. Taking 75."
Are you taking this medicine?
Your review helps others make informed decisions.- MCh...
- June 6, 2016
Diclofenac / misoprostol for Rheumatoid Arthritis "I have had RA for 6 years. Recently, I changed doctors, and he suggested Arthrotec as it was discovered I have early onset OA as well. I needed something else besides Metho and Humira. Let me say, Arthrotec is AMAZING, I hadn't felt so good in years! I am 35 years old, and I was able to play with my kids, run around, which I haven't been able to do. All was great until I ended up in the ER. I thought I was having a heart attack. Luckily, it was not, but it was an ulcer. At least I had a little time with my kids."
- pai...
- Taken for 1 to 6 months
- May 31, 2015
For Osteoarthritis "I was taking diclofenac-misoprostol 75-200 TB twice daily. It caused me to have gastritis so severe that I thought I would die. Had to stop taking it and begin another medication for my stomach. Don't like it at all."
- FLA...
- Taken for 2 to 5 years
- March 1, 2018
Diclofenac / misoprostol for Osteoarthritis "I have multiple sclerosis (MS) and severe arthritis. The pain of arthritis is difficult sometimes to define from the other pain effects. If I fall, which is often, that pain is much worse. Lately, I was stupid, so I increased the Arthrotec after having frequent falls and finding the pain too much. Because of the higher dose, now I have edema (swelling) in my legs and feet. I must start weaning back to a lesser dose since edema may not be likely, but it is listed as a possibility. Even with my MS, I never had edema. I have to wing it from here. I'd rather have pain from age-old arthritis than edema because I stupidly thought a rather low dose would be a good thing to increase without considering the cost of really bad side effects. Lesson to take away: leave the dosing to your doctor and don't play at being a know-it-all because that never, ever works."
- 11Q...
- May 26, 2018
Diclofenac / misoprostol for Rheumatoid Arthritis "Suffering from RA, osteo, fibro, and Sjögren's. Diagnosed at 41, am now 53. On Enbrel and Arthrotec 75. This combination works very well for me, I still have pain, but it is manageable. I tried to do generic Arthrotec, but it did not work. I usually take one tab before bed. If I am going to be very active, I will take one in the morning as well, but that is rare. The gas and stomach upset are expected, along with feeling very hungry, and I do have bathroom issues from it. I have lost weight while taking this. I believe a lot of inflammation stems from the digestive tract, and when it is emptied, I suffer a lot less. I will watch my kidneys, but as for this med, I love it, and the pros outweigh the cons."
- 06H...
- June 2, 2017
Diclofenac / misoprostol for Sciatica "Started taking this medication about a week ago for sciatica-related pain. I had L5-L6 back surgery 10 years ago and get flare-ups of pain from post-surgery. It has helped the pain a fair bit. I still feel the right buttock pain when driving my car, but other types of sitting are much better. The side effects are not so good: a lot of bloating. I feel like I have a balloon in my tummy, upset stomach, lightheadedness, and dizziness. With having vertigo in the past, it's hard to tell if it's vertigo or the medication. The doctor wanted me to try it for 2 weeks, but I will go see him today after 1 week and have a chat with him about it. My dosage is 2 pills per day with food, 50MG. I will ask if taking 1 per day may be a good idea, and who knows, it may be enough."
- Thr...
- Taken for 2 to 5 years
- July 11, 2018
Diclofenac / misoprostol for Rheumatoid Arthritis "I have been diagnosed with RA, and X-rays also show degenerated disk disease. I usually take Celebrex, but when my back flares up, I go to the one and only Arthrotec 50 mg, twice a day. I can actually get back on the treadmill again. The only medication that loosens up my back. A wonder drug!"
- Lau...
- Taken for less than 1 month
- April 8, 2018
Diclofenac / misoprostol for Osteoarthritis "After taking two 50 mg doses am and pm, I am having to sit up in bed, hoping that the gas and stomach upset will pass so I can get some sleep. I did notice some pain relief, but I won't take it again due to the stomach upset."
- Ano...
- Taken for 1 to 6 months
- November 13, 2023
Diclofenac / misoprostol "Two very effective medications combined is very convenient. However, it's still hard on the stomach. The misoprostol dosage should be higher, perhaps 300mcg with the 50mg and 400mcg with the 75mg. Also, diclofenac is hard on the kidneys. But used 2 days a week it is very effective."
- Lai...
- Taken for 1 to 2 years
- August 28, 2017
For Osteoarthritis "I have been taking this medication for well over a year now, and I am totally satisfied. It has made my arthritis bearable. Even though my prescription allows me to take 2 a day, so far I have only taken 1 before bedtime. I am nearly 76 years old. My husband, who is 65, started taking the same medication, but he takes at least 2 every day. He also has 2 slipped discs from a back injury along with the arthritis."
- Ano...
- June 20, 2019
For Osteoarthritis "I couldn’t take Celebrex for more than 3 days in a row because it would cause stomach pain, but I had found relief from arthritis pain only if I took the recommended dose. One day, my orthopedic doctor gave me samples of Arthrotec 75 to last until a new re-supply of Celebrex came in through my mail-order pharmacy. With the very first Arthrotec, I got complete relief from my arthritis aches and pains. As a result, I decided to wait until my pain came back before taking another. I was able to wait several days before needing another (I’m patient with pain as long as I can function without medication), and I found that I got complete relief with each tablet. I never take 2 a day, and I never have to take them for 2 days in a row. I never went back to Celebrex, incidentally. I recommend taking Arthrotec only as needed due to the risks involved with ANY medication. I can honestly recommend it to anyone except a high-risk patient. The effects are dramatic."
- T Z...
- September 3, 2016
For Osteoarthritis "Very helpful with arthritis pain, but side effects outweigh helpfulness. I noticed nausea, severe leg cramps, feeling uncomfortable after eating a small amount of food, fast weight gain. The main reason I quit this medication was because I felt it was making my antidepressant medication (Effexor) way less effective."
- Jak...
- Taken for less than 1 month
- September 26, 2020
"I crashed mountain biking. I went to the emergency, and the doctor wasn't very good. Six days later, I went to my family GP in excruciating pain after taking Advil for six days. He prescribed 75 mg every 12 hours, and after 30 minutes, much of the pain was gone. I am waiting for an X-ray and ultrasound to confirm the doctor's diagnosis."
- 06H...
- Taken for 1 to 6 months
- October 22, 2017
For Sciatica "After taking 50 mg twice a day for a few months, the pain started coming back. I talked to my doctor, and we are currently trying 75 mg twice per day. After about a month, I have decided it may be time to slowly go off it, as it is not really doing a whole lot to relieve my lower right buttock pain that radiates down my leg/hamstring/calf and into one side of my foot. The only other med on file from the surgeon who did my L5-L6 operation a few years ago is Lyrica. The side effects that they show on TV are quite numerous, but I may have no other option but to try it."
- Mar...
- Taken for 1 to 6 months
- July 20, 2021
Diclofenac / misoprostol for Osteoarthritis "Arthrotec 75 tablets taken twice daily as prescribed by one doctor resulted in a severe stomach ulcer requiring an antacid medication regimen for 30 days. Also, a blood test was performed. Arthrotec is only made in non-coated form, so it will not protect the stomach lining and should not even be approved for use!!"
- Anonymous
- Taken for less than 1 month
- July 5, 2017
For Sciatica "Lower right hand back started acting up. So mornings are not great. I am taking diclofenac/misoprostol 50 mg/200 mcg, 2 pills a day. It has given back my quality of life. I thought I would try just one in the evening, was a bad idea. Take after a meal with a full glass of water, np."
- Sam...
- Taken for 2 to 5 years
- November 19, 2022
For Rheumatoid Arthritis "I have used Diclofenac Gel for the last few years. My hip can be very painful to the point that I can hardly turn it from side to side. I can spread a small amount of gel on the area that pains me, rub it in well, and the pain just melts away. I have no side effects from the gel and I use it as directed. I wish I could take Diclofenac pills. I am unable to because I have early kidney disease due to my diabetes and gastroparesis. Reading all these reviews makes me want to run it by my doctor again!"
- Anonymous
- September 2, 2008
Diclofenac / misoprostol for Sciatica "I have a bulging disc on my L5 that is pinching my sciatic nerve. Arthrotec started working right away. I only take one a day. No side effects yet."
- kak...
- Taken for less than 1 month
- February 26, 2013
Diclofenac / misoprostol for Osteoarthritis "Just started taking Arthrotec, but I can tell a difference already. I have less pain. I also feel very hungry and nauseous. I've had a little dizziness too."
- Anonymous
- January 1, 2012
Diclofenac / misoprostol for Osteoarthritis "For people suffering from inflammation, this medication is amazing! After 2 days, my pain was gone. No long-term regimen. I've suggested this medicine to many people."
- Her...
- Taken for 10 years or more
- December 12, 2012
Diclofenac / misoprostol for Rheumatoid Arthritis "I have been taking this for 12 yrs, made a big difference in my life. Tried every medicine, and none had the same effect. Take two pills a day, 3 upsets my stomach. Without this, I would be bedridden."
Are you taking this medicine?
Your review helps others make informed decisions.More about diclofenac / misoprostol
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: Nonsteroidal anti-inflammatory drugs
- En español
Patient resources
Other brands
Professional resources
- Diclofenac and Misoprostol Delayed Release prescribing information
- Diclofenac and Misoprostol Tablets (FDA)
For Osteoarthritis "I was prescribed 50-0.2 mg twice a day. This medicine did work to relieve my back pain, but it came at a cost. It caused me to have severe stomach cramps and constantly feel nauseous. I had to stop taking the medicine because of this problem."