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Intrarosa and Irritability: What Users Say

Irritability: mentioned by 5 users (4.5%)

Based on user experiences from 111 Intrarosa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hair loss 12.6%
discharge 7.2%
burning 6.3%
cramps 5.4%
mood swings 5.4%
weight gain 5.4%
hot flashes 4.5%
insomnia 4.5%
irritability 4.5%
anxiety 3.6%

Reviews for Intrarosa

  • Mad...
  • Taken for 1 to 2 years
  • December 16, 2020

For Dyspareunia "Intrarosa helped in that it made sex a 'bit' less painful, but I am having significant hair loss and irritability. The residue did stain my pajamas, but OxiClean spray got them out. I started noticing a darkness around my pelvic area on my legs. Today I noticed odd dark spots on the top of my legs in my groin area. What is this? I have experienced weight gain, irritability, bloating, gas, major hair loss, and weird discolored spots in my groin area. I am so thankful to all the women who have shared their experiences. I was really troubled by the hair loss especially."

2 / 10
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  • Jan...
  • Taken for 6 months to 1 year
  • February 7, 2021

For Dyspareunia "I came off Intrarosa 3 months ago, and I’m feeling more like me, on a REALLY good day, most of the time. I didn’t realize how irritable and miserable it had made me. I was so desperate to find something to help that I persevered for 8 months (I’d already been on Vagifem for 18 months, without any significant changes). I decided to stop, have a break, and start again. Since stopping it, I’ve realized that it didn’t help with the pain one little bit and turned my desires completely off. Now my libido is much better, there is still discomfort on penetration, but it doesn’t feel as sore during, and I enjoy sex a bit more nowadays (instead of wishing it would end). I do use a lot more water-based lube than ever before (from Yes Yes Yes) which really helps. I’m in a much better place emotionally without Intrarosa (and Vagifem), and my husband agrees. Intrarosa definitely didn’t work for me. (I’m 56, had a total hysterectomy 10 years ago, and use Oestrogel HRT)."

1 / 10
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27 Report
  • Mis...
  • Taken for 6 months to 1 year
  • August 5, 2018

For Dyspareunia "After about 3 months of using Intrarosa, I felt I was having positive benefits with improvement of vaginal tissue. After that, I began to have terrible hot flashes (which were previously very infrequent and mild). I felt agitated and had an episode of crying that I could not control. Around 6 months of use, my blood pressure (which was never a problem) suddenly spiked to a dangerous level, and I ended up in the hospital. I discontinued using Intrarosa. Lots of tests later, and the doctors cannot say definitively that my problems were directly related to Intrarosa. I think they were, as all the symptoms have gone away, my hot flashes are back to 'normal,' and I feel like myself again. I'm now using coconut oil for lubrication, and so far, so good ;)"

2 / 10
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42 Report

Frequently asked questions

  • Man...
  • Taken for less than 1 month
  • August 10, 2020

For Dyspareunia "I have been taking Intrarosa for almost 3 weeks. I have been having severe headaches every day. I am going to stop taking it for a few days to see if it is from this medication. Really irritable too."

3 / 10
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15 Report
  • Ano...
  • Taken for less than 1 month
  • November 12, 2022

For Dyspareunia "I only tried it once. I have a history of depression and migraine. It made me very depressed and irritable and made my migraines worse. What a waste of money."

2 / 10
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7 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.