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Eucrisa and Pain: What Users Say

Pain: mentioned by 22 users (7.7%)

Based on user experiences from 284 Eucrisa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 54.9%
itching 14.1%
stinging 10.9%
pain 7.7%
rash 3.5%
swelling 2.1%
tingling 2.1%
redness 1.8%
discomfort 1.4%
irritation 1.4%

Reviews for Eucrisa

Commonly mentioned side effects
  • Fla...
  • May 16, 2019

For Atopic Dermatitis "I can't remember the last time I cried before using Eucrisa. I now can point out the exact date. May 15, 2019. Today was the 5th application, and holy moly, my eyeballs had flames protruding from them for the last 10 minutes. I had some odd swelling, redness, and irritation on both eyelids and below the eye. I put Eucrisa on them and was happy that it alleviated the symptoms with little discomfort. Until today... My symptoms were raw, just like my flaming eyelids. This may be the source of the most pain I have experienced for 8 minutes. I closed my eyes, fanned with my hands, put a water bottle on them, and hoped it didn't blind me if it made its way down. It didn't, and I still have the gift of sight. Eucrisa is very effective but feels like hemorrhoids on your eyes (if this is where you are affected). The pain lets you know it is working. Again, the first 6 applications were tolerable. I paid $10 for this giant tube of flames with a coupon."

9 / 10
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44 Report
  • HJa...
  • Taken for less than 1 month
  • January 10, 2020

For Atopic Dermatitis "This ointment creates a very intense burning/stinging sensation, difficult for me as an adult to tolerate. I suffered through the first application, the next day, the second application was even more intense, and I had to wash it off. PLEASE NEVER USE THIS PRODUCT ON A CHILD!!! The pain is too intense."

1 / 10
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18 Report
  • Anonymous
  • Taken for less than 1 month
  • July 21, 2017

For Atopic Dermatitis "I have always been prescribed a mild steroid for my facial eczema, so I was happy to try Eucrisa as a steroid-free treatment for my face. The stinging and burning are so uncomfortable that I'm not sure the results are worth it for me. The medication does help calm down flare-ups and reduce any itching, but the pain for the first 5 minutes after application is so severe on my face that sometimes I have to just wash it off and try the next day. The site pain on the body is way more tolerable, and I do recommend it for that! Maybe my face is just too sensitive, but I'm going to keep trying."

5 / 10
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18 Report

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Frequently asked questions

  • BMa...
  • Taken for less than 1 month
  • February 21, 2019

For Atopic Dermatitis "As others have experienced, when applied to the face, this feels like acid. Perhaps because the skin is more sensitive here, the pain lasts about half an hour. After using daily for a few weeks, it hurts less, or it is quite possible my pain tolerance has increased... but the presumed areas of eczema haven't shown improvement. For this level of pain, I was expecting a better return. I'm giving it a full month, though, to work its magic."

1 / 10
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14 Report
  • Tbe...
  • March 18, 2017

For Atopic Dermatitis "I've had eczema my entire life. For as long as I can remember, I've been itchy. You name it, I've tried it. From all-natural remedies to every prescription cream, ointment, and pill. I've only been using this ointment for 2 days, and I noticed a difference within hours. The itching is completely gone, and my skin is noticeably softer (to me at least). I didn't have any irritation or pain on the affected sites. So far, I'm very pleased. I'm using it as a free trial from my dermo, and she and I are both hoping it's a game changer that will soon be covered by insurance."

9 / 10
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19 Report

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  • Jil...
  • July 12, 2017

For Atopic Dermatitis "This cream not only caused me pain, but it caused my eczema to itch 100x more. It also dried my skin up to the point where my skin would crack and start to peel. I'm disappointed not only because it cost me $70, but because I was excited for a new solution to my eczema that didn't require steroids."

2 / 10
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15 Report
  • Pip...
  • March 20, 2019

For Atopic Dermatitis "I am torn on how to review this. Luckily, my dermatologist warned me about possible burning and suggested I mix it with face lotion. I tried this and, dear god! It burned like nothing I have ever felt. I was tearing up and actually sweating from the pain, which caused more hurt, even so I had to remove it. I eventually figured out if I put on a layer of Aquaphor (which has a similar consistency) and then put on a little Eucrisa, it was manageable but still quite painful (would have a glass of ice water and an ice pack ready to immediately apply to help). This actually did seem to help, and my skin felt smoother and saw less flaking, but I just couldn’t face this torture every day. I hoped the burning would decrease like some other reviewers experienced, but it never did."

7 / 10
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11 Report
  • Red...
  • Taken for less than 1 month
  • June 8, 2019

"I'm surprised nobody has mentioned this before: Eucrisa does NOT absorb into the skin... it merely 'sits on top.' It's sticky, like Vaseline, and if you use it on your face (like I did), you'll be walking around with a wet, shiny face all day. It didn't work at ALL for my condition (rosacea), and it burned... it was very painful, and it made the redness and swelling worse. I'm not a chemist or anything, but this is the first time I've used a topical medication that didn't absorb into the skin. It makes me wonder how a drug could possibly work at all if it isn't absorbed?"

1 / 10
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13 Report
  • Kya...
  • August 17, 2017

For Atopic Dermatitis "I was able to get Eucrisa for $35 for a full 60-gram tube. I was temporarily on Elidel, which seemed to help my frequent flare-ups on my hands calm down. It seems my eczema has gotten so much worse with Eucrisa. I have rash-like bumps all over my hands, intense itching, and pain to the point where I don't even want to go to work, and they felt like they were on fire. I didn't know what to put on my hands to stop the intense itching, so I went back to applying my son's triamcinolone cream to my hand, and the pain went away within a half an hour. I'm really unsure if I want to continue using the Eucrisa, I have not noticed any improvement in my skin. I've been on it twice a day for at least a week."

1 / 10
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15 Report
  • Joe...
  • Taken for 1 to 6 months
  • April 19, 2017

For Atopic Dermatitis "I have severe eczema. Prednisone or tacrolimus will clear me up, but steroid topical medications only help a little. I was excited to hear about a new treatment. The tube cost 80.00 after insurance. I didn't notice any pain or discomfort, but I didn't notice any positive effect either. It did nothing for my itch. I decided to try it on one leg with triamcinolone ointment on the other. The triamcinolone worked noticeably better. I did not refill my prescription."

1 / 10
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12 Report
  • Kat...
  • Taken for less than 1 month
  • January 5, 2019

For Atopic Dermatitis "This medication burns like someone is pouring acid on your face. After using it the first time at night (which I cried because it burned so bad), my face became less red after 30 minutes to an hour, but by the next day it looked exactly the same as it had prior to using the cream. My dermatologist recommended that I put facial lotion on first and then apply the Eucrisa to prevent it from burning, but that turned out to be a laughable solution. The second day, I had to talk myself into applying it on my already sore face. It burned for 30 minutes. I have applied it for 5 days now and my eczema is exactly the same; all over my face, weeping, bright red, and itchy. I give up and I really hope my dermatologist can find something else because it is just not worth the pain for no result. I really wanted this to work. The only positive thing I can say is it applies easily and my dermatologist provided me with a coupon that made it $30. Not a fan."

2 / 10
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9 Report
  • Anonymous
  • Taken for less than 1 month
  • December 18, 2018

For Atopic Dermatitis "I have had horrible psoriasis for over 5 years on my hands. I have tried every steroid cream to no avail. The psoriasis covered the palms of both of my hands and was very painful, with constant fissures. Within 1 day of using Eucrisa, there was a noticeable difference. I have now been using it for a week, and I feel like a new person. I have experienced no stinging or pain, and the results are a miracle. This is the first time I have seen any improvement with a treatment for my psoriasis."

10 / 10
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8 Report
  • Mar...
  • Taken for 1 to 6 months
  • October 16, 2019

For Atopic Dermatitis "My granddaughter was prescribed this, she is 3 years old. She has used steroid cream for a couple of years, so the dermo wanted to try her on something else. This medication made her eczema worse, and also that poor baby screamed bloody murder every night that I applied this, meaning for a month straight. I wouldn't pay $5 for this medication, much less want anyone to endure such pain after paying out $1,000 for the medicine."

1 / 10
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8 Report
  • Min...
  • Taken for less than 1 month
  • August 16, 2019

For Atopic Dermatitis "Don't try this! I've been battling atopic dermatitis/eczema for 30 years, and Eucrisa is the WORST treatment I've ever tried. I put it on my face, and it burned with the most excruciatingly deep pain you can ever imagine. I can't describe how horrific it was, like a horror movie. I was screaming and crying, but there was no way to wash it off (actually, I wanted to claw my face off), and it took a while before the pain went away. I looked online and found other similar experiences. I can't believe they let this ointment on the market and that all these doctors are pushing it. Shame on you!"

1 / 10
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  • Owl...
  • Taken for 1 to 2 years
  • September 13, 2018

For Atopic Dermatitis "I have been using Eucrisa for a year now; I use it primarily in the winter months, and when needed through the spring and summer. It has worked better for me than any other cream, ointment, or oil for my eczema, which I suffer from around the eyes. It is safe to use, unlike steroidal medicine. HOWEVER, putting this ointment on has to be the worst feeling of pain I’ve ever experienced... 60 seconds of a fiery, burning sensation takes over, and I can’t do anything but cry and suffer through it to get the results. Granted, my eczema is in a very sensitive spot, yet is very intense. If you have little to mild eczema (especially in a non-sensitive area), I HIGHLY recommend Eucrisa. But for me, it’s not worth the pain."

6 / 10
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6 Report
  • Dom...
  • Taken for less than 1 month
  • June 5, 2018

For Atopic Dermatitis "I’ve had eczema my entire life. I’ve never once had completely clear skin in almost 50 years. I started using Eucrisa yesterday, and the rashes are already clearing, the itch is almost completely gone, and for the first time, I am hopeful to finally have clear skin. Unlike many users, I experience no burning or pain when applied. It’s expensive, but so worth it to me."

10 / 10
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6 Report
  • Kie...
  • Taken for 1 to 6 months
  • December 3, 2017

For Atopic Dermatitis "My 8-year-old daughter has had severe atopic dermatitis and eczema, exacerbated by allergies, almost her whole life. It's so severe that her skin is consistently like raw meat, cracked open, and bleeds. This medicine says not to use on irritated skin. Is that a joke? Because the condition it claims to treat is, in fact, what it says to not use it on. Adding further insult is the excruciating pain that comes along with the treatment. My daughter says she'd rather deal with the bullying, torment, unsightlyness, itching, irritation, pain, and bleeding than use this medicine. How sad they develop a medicine that causes more pain than it's worth for children. I thought perhaps my daughter's struggles would be cured. Back to the drawing board, folks."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 30, 2018

For Atopic Dermatitis "It burns like fire!! Have to apply it around my eyes, and I almost screamed, so put a cooling gel pad on it, and after 3 (very long) minutes, the pain was gone. But I have been having rashes around my eyes for 10 years, so that skin is less than thin! So I am giving this a try... need to wait a couple of days to see if this helps..."

7 / 10
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4 Report
  • Tis...
  • Taken for less than 1 month
  • October 26, 2018

For Atopic Dermatitis "My skin started drying up really bad due to the cold weather. My dermatologist gave me a sample of Eucrisa. Before even trying it, I put in my prescription and was told it was not covered and was over $400. The pharmacist advised me to try the sample I was provided because a lot of customers were complaining about it. I tried it for the first time today on my face, and it burned and stung. It is very painful. I will go back to my usual prescribed ointment."

3 / 10
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4 Report
  • tee...
  • Taken for 6 months to 1 year
  • November 13, 2021

For Atopic Dermatitis "I struggled with severe eczema on my eyelids, breast area, armpit region, neck, etc., starting on a random day in 8th grade. I didn’t know what was wrong with me for so long, I suffered from embarrassment and shame until I found this product. My doctor just simply prescribed me a tube, and when I use it regularly, my eczema just disappears no matter how bad I was itching previously. I know it won’t work for all people, but the burn is worth it. It hurt worse than anything the first time I used it, but now it’s not bad at all. 100% worth it, and I totally recommend it if your natural treatment just doesn’t work."

10 / 10
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1 Report
  • Eza...
  • July 25, 2021

For Atopic Dermatitis "I've had moderate eczema since childhood, but in the past year, experienced the worst flare-ups I've ever had on my face and neck. After changing diets and trying every over-the-counter cream in existence, I saw no improvement. My neck lesions were so bad I could barely turn my head, and 90% of my face was red with blotchy, scaly skin. My mental health was in decline, and I was embarrassed to go out in public unless it was a necessity. My partner dragged me to the doctor, and I was prescribed Eucrisa with a card, which meant I got it for free (thank you, Canadian healthcare!) Honestly, the pain wasn't much worse than the pain I was already in with my open-wound skin. After day 1 (literally two uses), my partner already noticed an improvement. I'm on day 3 now, and almost every red patch on my face is gone. My neck lesions are gone. Not sure what kind of magic is in that tube, but it's given me the relief I never thought I'd get. This stuff is a game changer."

10 / 10
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1 Report
  • Jen...
  • Taken for less than 1 month
  • August 27, 2018

For Atopic Dermatitis "Eucrisa just made my eczema worse. It got more red, inflamed, and painful when I put it on. Would not recommend."

1 / 10
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5 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.