Crisaborole Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the use of topical crisaborole during breastfeeding. Some experts recommend avoiding its use during lactation because of the lack of information.[1,2] In general, drugs applied to the mother’s skin are unlikely to affect the breastfed infant unless it is applied to the nipple or other area where the infant can directly ingest it. Use of crisaborole in nursing mothers is not contraindicated by the product labeling,
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
1.
Vestergaard C, Wollenberg A, Barbarot S, et al. European task force on atopic dermatitis position paper: treatment of parental atopic dermatitis during preconception, pregnancy and lactation period. J Eur Acad Dermatol Venereol 2019;33:1644-59. [PubMed: 31231864]
2.
Yaghi M, McMullan P, Truong TM, et al. Safety of dermatologic medications in pregnancy and lactation: An Update - Part II: Lactation. J Am Acad Dermatol 2024;91:651-68. [PubMed: 38280680]
Substance Identification
Substance Name
Crisaborole
CAS Registry Number
906673-24-3
Drug Class
Breast Feeding
Lactation
Milk, Human
Enzyme Inhibitors
Phosphodiesterase Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
