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Crisaborole topical Side Effects

Medically reviewed by Last updated on Aug 31, 2022.

For the Consumer

Applies to crisaborole topical: topical application ointment

Side effects requiring immediate medical attention

Along with its needed effects, crisaborole topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking crisaborole topical:

Less common

  • Burning, stinging, swelling, or irritation of the skin
  • difficulty with breathing or swallowing
  • fast heartbeat
  • hives or welts, itching, or skin rash
  • redness of the skin
  • swelling of the face, throat, or tongue

Incidence not known

  • Blistering, burning, crusting, dryness, or flaking of the skin
  • itching, scaling, severe redness, soreness, or swelling of the skin

For Healthcare Professionals

Applies to crisaborole topical: topical ointment


The most frequently reported side effect was application site pain.[Ref]


Common (1% to 10%): Application site pain[Ref]


Frequency not reported: Contact urticaria[Ref]


Frequency not reported: Hypersensitivity reaction[Ref]

Frequently asked questions


1. "Product Information. Eucrisa (crisaborole topical)." Anacor Pharmaceuticals, Inc. (2017):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.