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Crisaborole topical

Generic name: crisaborole topical [ KRIS-a-BOR-ole-TOP-i-kal ]
Brand name: Eucrisa
Dosage form: topical ointment (2%)
Drug class: Miscellaneous topical agents

Medically reviewed by on Apr 25, 2022. Written by Cerner Multum.

What is crisaborole topical?

Crisaborole topical (for use on the skin) is used to treat mild to moderate eczema (atopic dermatitis) in adults and children who are at least 3 months old.

Crisaborole topical may also be used for purposes not listed in this medication guide.


Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use crisaborole topical if you are allergic to it.

Tell your doctor if you are pregnant or breastfeeding.

Crisaborole topical is not approved for use by anyone younger than 3 months old.

How should I use crisaborole topical?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Avoid getting crisaborole topical in your eyes, mouth, or vagina.

Rinse with water if this medicine gets in your eyes or mouth.

Do not share this medicine with another person, even if they have the same symptoms you have.

Apply a thin layer to the affected skin.

Wash your hands after applying this medicine, unless you are using it to treat eczema on your hands.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Store at room temperature away from moisture and heat. Keep the tube tightly closed when not in use.

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

An overdose of crisaborole topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using crisaborole topical?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Crisaborole topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching, skin redness or swelling; difficult breathing; swelling of your face, lips, tongue, or throat.

crisaborole topical may cause serious side effects. Stop using crisaborole topical and call your doctor at once if you have:

  • severe itching, redness, or swelling of the skin where the medicine was applied.

Common side effects of crisaborole topical may include:

  • pain, burning, or stinging where the medicine was applied.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Crisaborole topical dosing information

Usual Adult Dose for Atopic Dermatitis:

Apply a thin layer to the affected area(s) twice a day

Use: For the topical treatment of mild to moderate atopic dermatitis

Usual Pediatric Dose for Atopic Dermatitis:

2 years or older: Apply a thin layer to the affected area(s) twice a day

Use: For the topical treatment of mild to moderate atopic dermatitis

What other drugs will affect crisaborole topical?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Frequently asked questions

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.