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Codeine / guaifenesin and Cough: What Users Say

Brand names: Cheratussin AC, Guaiatussin AC, Virtussin A/C, Guaifenesin AC, Cheracol with Codeine, Robafen AC, Gani-Tuss NR, Guaitussin AC, Codar GF, Mar-cof CG, Bitex Liquid, Allfen CD, Allfen CDX, Mytussin AC, Guiatussin with Codeine, Glydeine, Guaifen-C, Guaifen AC, Codafen, Guai-Co, Duraganidin NR, Diabetic Tussin C Dex-Tuss ExeClear-C Guiatuss AC Brontex M-Clear WC Pro-Clear …show all brand names

Cough: mentioned by 8 users (9.2%)

Based on user experiences from 87 Codeine / guaifenesin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 12.6%
cough 9.2%
chest pain 4.6%
drowsiness 4.6%
nausea 4.6%
sore throat 4.6%
insomnia 3.4%

Reviews for Codeine / guaifenesin

Commonly mentioned side effects
  • Anonymous
  • January 20, 2010

Codeine / guaifenesin for Cough "This did little for my cough - still waking up in the middle of the night with coughing fits. Even when I take another dose at night, it doesn't help. In fact, I've now woken up every night while I've been taking this, so I will stop."

2 / 10
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27 Report
  • Ano...
  • Taken for less than 1 month
  • March 18, 2023

For Cough "After 3 weeks of a nagging cough, 1.5 bottles of NyQuil later and completed taking antibiotics, steroids, an inhaler, and the pearls, went back to urgent care. He assured me I would sleep with this as I haven’t had a full night's sleep in 3 weeks. The pharmacist mentioned it’s way better than NyQuil and I’ll sleep great. Not at all. I’m coughing so much and not tired at all. My chest and head hurt so badly from all the coughing. It gets to a point that you just cry. I don’t recommend this medication. Back to NyQuil, I guess."

1 / 10
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3 Report
  • Cou...
  • Taken for less than 1 month
  • December 26, 2016

Codeine / guaifenesin for Cough "Been incredibly frustrated with a virus that turned ugly and a strong, intense cough that caused pulled muscles, raw throat, and coughing up blood. This drug was prescribed with a decongestant and antibiotics. I still cough occasionally, but this is a huge improvement from the intense nonstop barking cough and gave my chest a chance to heal."

7 / 10
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7 Report
  • Ano...
  • Taken for less than 1 month
  • January 13, 2017

Codeine / guaifenesin for Cough "I tried this for the first time, and it kind of worked. I am still coughing a little, but not as much. I do still kind of taste it in my mouth, which is weird, but I would use it again if it was the only medicine I had. However, I will be looking for a new medicine."

6 / 10
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6 Report
  • Kat...
  • Taken for less than 1 month
  • January 3, 2020

For Cough "It’s terrible. I took it at bedtime and drank enough water as the instructions said. I woke up in the middle of the night two days in a row and coughed like crazy. The doctor in the urgent care prescribed me this medicine to help me sleep better at night, but I don’t think it’s working well for me. The price is about the same as a bottle of Mucinex nighttime."

1 / 10
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3 Report

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  • sle...
  • Taken for less than 1 month
  • October 24, 2018

For Cough "This stuff is awful. The first time I took it, it helped put me to sleep for an hour, and I woke up with an awful coughing attack and then barely slept through the night. The second night I took it, I was awake the entire night, coughing worse than not taking anything. Mucinex DM has the same active ingredient and works 1,000 times better, and NyQuil always knocks me out all night. I’m going to stick with over-the-counter meds."

1 / 10
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3 Report
  • nat...
  • March 30, 2009

Codeine / guaifenesin for Cough "I was using Mucinex DM and just wasn't doing the trick for me. I wasn't sleeping at night. So got this, and I am slowly getting back to sleeping without being interrupted with coughing."

9 / 10
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31 Report
  • Sle...
  • Taken for less than 1 month
  • December 31, 2019

For Cough "This drug is awful, the urgent care prescribed it to help suppress cough so I could sleep. It did the opposite. I’m coughing constantly and can't sleep at all. I’ll never take this again."

1 / 10
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5 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.