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Chlorthalidone and Weakness: What Users Say

Brand names: Thalitone Hemiclor

Weakness: mentioned by 6 users (12.2%)

Based on user experiences from 49 Chlorthalidone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 16.3%
increased heart rate 12.2%
nausea 12.2%
rash 12.2%
weakness 12.2%
tiredness 10.2%
cramps 8.2%
fatigue 8.2%
headaches 8.2%
migraine 8.2%

Reviews for Chlorthalidone

Commonly mentioned side effects
  • TTa...
  • Taken for less than 1 month
  • November 16, 2020

For High Blood Pressure "Chlorthalidone helped me with my blood pressure to go down but the side effects were just too much. I felt high and drunk on this medicine and I had only taken it for 3 days. The feeling would come in waves. I was prescribed 25mg once daily. My vision was very blurry and I became very confused and disoriented. It became difficult to walk. My legs cramped. I had heart flutters and irregular heartbeat for a few minutes. I had horrible anxiety and panic attacks on this med. I also had sharp pains in my toenails and my fingernails. My voice became hoarse and my eyes became bloodshot red with lots of pressure in my eyes. The room was spinning and I kept getting dizzy spells when I walked. I could not function on this. I could not concentrate or complete my daily tasks. I slept most of the day because of it. I stopped taking it and I feel better more and more every day. It was extremely scary to be on! I will never take this medicine again! It is definitely not for me!"

5 / 10
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144 Report
  • Fra...
  • Taken for 6 months to 1 year
  • July 1, 2014

For High Blood Pressure "I have been on a lot of this type of medication. Benicar almost did me in, and I was traveling far from home. Different doctors have prescribed a lot of different meds. I cannot take this type of pill. I almost become crippled with chlorthalidone. It weakens my knees, legs, and ankles. I am a type II diabetic on insulin. My morning glucose tests run between 230 and 246."

3 / 10
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57 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • April 7, 2023

For High Blood Pressure "I was started on chlorthalidone because losartan didn't lower my blood pressure, and I was having too many side effects with lisinopril. It lowered my blood pressure well for a few months and then seemed to stop working. During these three months, I was also dealing with heart palpitations. I completely stopped caffeine and alcohol. I had a Holter monitor test and was told I was experiencing harmless PVCs and PACs. My doctor doubled my chlorthalidone to try to get my BP back under control, and then I started to feel really terrible. Headaches, muscle cramping all over my body, weakness, fatigue, frequent heart palpitations. I thought it was just a little bit of dehydration since this medication is a diuretic, but my labs showed that my potassium dropped to severely low. I was taken off the medication and had my potassium replaced. Once my potassium was back to normal, I started to feel better, and after a few weeks, I also noticed that my heart palpitations had completely stopped."

2 / 10
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7 Report

Frequently asked questions

  • Dak...
  • Taken for less than 1 month
  • April 4, 2023

Chlorthalidone for High Blood Pressure "Just started taking this a week ago. Has not yet effectively lowered BP 150/90. I have had side effects of cold sweats, weakness, nausea, and erectile dysfunction, in order of severity. Planning to contact my doctor if symptoms do not lessen within another week."

1 / 10
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6 Report
  • Jta...
  • Taken for 1 to 6 months
  • December 22, 2019

For High Blood Pressure "It worked well at decreasing my systolic BP but gave me horrible migraines. I also had pins and needles in my feet, and some days I felt really weak and out of it, like I had an electrolyte problem."

4 / 10
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19 Report
  • Nie...
  • Taken for 1 to 6 months
  • August 15, 2021

For High Blood Pressure "Makes my legs feel like wet noodles; very weak and tired. Is this medicine or poison?"

7 / 10
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12 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.