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Wellbutrin SR for Depression User Reviews (Page 4)

Reviews for Wellbutrin SR

Commonly mentioned side effects
  • kke...
  • February 22, 2009

"I started Wellbutrin 5 days ago. The first night I felt like my heart was racing and pounding, but it went away the next day. Then at work, for the past 2 days, I have been sweating excessively and getting the feeling that I need to sit. Last night, after taking the medication for 5 days, I had the feeling that my head weighed a thousand pounds, and I just felt so dizzy, lightheaded, and weak I could barely walk right. I went to lay down to sleep, and all of a sudden I couldn't swallow and was gasping for air. It was so scary. I just couldn't catch my breath. I could feel my throat closing up. I was rushed to the E.R., and they found I was having an allergic reaction to it."

3 / 10
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37 Report
  • Mis...
  • July 30, 2016

"I rated it a 5 because I felt for me it was 50/50. Tomorrow will have been only my 5th day taking the generic version (bupropion SR), but I am making today the last one. I was prescribed only 150 mg once a day. The first 3 times I took it, it worked wonderfully. I experienced a handful of side effects that were super mild, but I felt great. I felt energized and positive. Today, on the other hand, about two hours after I took my dose, I was hunched over the toilet, almost throwing up with bad stomach pain in addition to the nausea. I never threw up. I have ZERO appetite and no energy and a bad sharp pain in my upper stomach. I feel totally disconnected from my body."

5 / 10
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30 Report
  • Anonymous
  • July 10, 2011

"I used this on and off for several years, never over 150 mg/day. I liked the energy it provided, the suppression of appetite, the low cost (without insurance), and the increased sex drive (as opposed to Prozac/Zoloft, which prevented me from reaching orgasm). The downside for me was increased sweating and anxiety. The anxiety was the worst. I now use Ritalin and prefer it."

7 / 10
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32 Report

Frequently asked questions

  • Joa...
  • November 8, 2018

"I feel the same way as someone else on here - super irritated and angry. Have ruminations of the past. I'm stopping it today. I have a mood disorder, and this makes it bad. Plus, I feel weepy too. I can deal with the depression until I find a better med."

5 / 10
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  • Msr...
  • Taken for less than 1 month
  • November 3, 2016

"Taking name brand. Started 150 1x a day for a week. First day so amazing, energized, went to the gym, positive, and for 4 days felt great. 5th not so much and by 7th day was feeling back to my depressed self, so I upped it to 2 a day. Now I go from anxious to flat. Feel absolutely nothing, zoned out, very irritable. Vivid dreams and nightmares, kind of can't separate dream from reality because it seems like someone's in the house and I wake up out of a dead sleep and I'm not sure if someone's in the house. Going to give this a few more days, if things don't get worse, hopefully they'll get better. If not, not going to take it anymore. I took this because I wanted to avoid weight gain, which happened years ago with other SSRIs. Hasn't affected appetite."

5 / 10
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  • Ale...
  • Taken for less than 1 month
  • April 22, 2016

"I started taking 150 mg twice a day, and I started feeling a difference since day 1. The very first night I woke up in the middle of the night, agitated because of a very vivid dream, and they only got worse as the days went by, to the point I could not differentiate dreams from reality and having a lot of trouble waking up. During the day, I was feeling hopeful again and started doing things I had stopped doing, but on day 7, approximately, I had a major panic attack at work, feeling like I was choking due to lack of oxygen and started hyperventilating, which I had never experienced before in my life. So, long story short, I ended up in the ER that night. Even though the paramedics suggested it was going to go away by itself, I still wanted to be checked out. Horrible experience."

1 / 10
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  • mih...
  • January 15, 2018

"I've been taking this medication off and on for quite a few years, and I have mixed feelings about it. If you want lots of energy, this is the stuff to take. If you have OCD or an anxiety disorder, you might want to pair this with some Effexor or Zoloft. I'm still in the process of figuring out a dose that works well for me. I'm on 450 mg XL and 75 mg Effexor XL. If you want to drink alcohol, keep it to a minimum, preferably no more than 3 beers. I personally find that it reduces my desire to drink, and I'm also going to ask my doctor about taking Contrave, which is 300 mg Wellbutrin and 12.5 mg Naltrexone for weight loss (Thanks, Effexor)."

6 / 10
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More FAQ

  • Nic...
  • January 25, 2021

"I don't find this an antidepressant rather than a demeanor stimulant/energy enhancer. Goes well with SSRIs, SNRIs, and many others as add-ons. Personally, on 150 mg daily, I found myself more energetic, needing less sleep, more able to focus for seriously long days, more outspoken, and also more irritable. Some restlessness or a stupor-kind of feeling for a couple of hours in the afternoon. All of this subsided as the months passed. 1-2 years led to some kind of tolerance. 300 mg doses seemed to give me some more focus but also made me feel a bit off. Enhances the focus a little more, and likely possible overt wakefulness, irritability, or confusion would subside over time. I still couldn't estimate needing such a dose myself. Initially, a combination of Sertraline made me hypermanic for a month or two: showed up at parties drinking and talking to everyone, making new acquaintances, life choices ultimately leading to major changes, etc. My psychiatrist didn't think it was a problem, though."

7 / 10
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  • Anonymous
  • December 15, 2010

"I have Major Depressive Disorder, anxiety, and severe ADHD. I took Wellbutrin for four days, and at first it was fine, then I quickly developed hot flashes and eventually started freaking out and having unrelenting suicidal thoughts. Guess it just didn't work for me, but it didn't make me tired."

1 / 10
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  • Anonymous
  • September 8, 2010

"I have been taking Wellbutrin SR 150 mg for five years. Have been doing really well, but here lately I have been really tired, low sex drive, wanting to eat when I am not hungry. Maybe I need an increase."

8 / 10
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  • PTS...
  • Taken for less than 1 month
  • September 11, 2018

"I recently had to move to a different city and to find a new doctor. So, he took me off Clonazepam 0.5 for anxiety. Instead, he prescribed Wellbutrin 150 mg 2x to go with my Zoloft 100 mg. I've never taken Wellbutrin, so why did he put me on a high dose right away? I'm irritated at the slightest thing. Trying to get a new psychiatrist."

4 / 10
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  • Pri...
  • Taken for 1 to 6 months
  • December 28, 2020

"I’ve been taking Wellbutrin for a couple months now, and honestly, mood-wise, I have been feeling better. I still have big mood swings (diagnosed with bipolar type 2), so it really could be that. Side effects I have noticed would be extreme agitation and severe acne, which honestly is disappointing because I used to have really clean and clear skin. Other than that, I think it’s pretty cool."

8 / 10
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  • Txm...
  • Taken for less than 1 month
  • December 15, 2015

"I started this after talking to my doctor about how I was scared to gain weight with an antidepressant (I gained 15 pounds on Zoloft). This medicine made me feel crazy! I took it for 2 weeks, and every day I felt like there was a brick on my eyes/head. I felt like I was going to have a seizure any moment (no, I've never had one, I just felt like I was going to). I was sensitive to light and couldn't see when I was driving at night. It was awful!!! I'm on Prozac now and seem to be doing ok :)"

1 / 10
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  • 601...
  • September 22, 2016

"I have been on this med for two weeks now and I have yet to feel any benefits while starting this med. My doctor told me to take it twice daily, they are 100 mg. I have been taking it but still feel the same."

2 / 10
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  • Ano...
  • Taken for 6 months to 1 year
  • December 30, 2018

"I took Wellbutrin 150 mg for 1 week, then 300 mg for about 5, maybe 6 months, and then my doctor increased my dosage to 400 mg mixed with 100 mg of Zoloft, and I'm shaky, irritated, and more prone to crying. I have split personality disorder, and it's been throwing me into different ones, and on top of that, I have PTSD and mood disorder, plus I'm bipolar type 2, and I've been thrown into my manic states more often. It sucks."

2 / 10
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  • Cou...
  • Taken for less than 1 month
  • February 13, 2021

"I started taking Wellbutrin SR 150 mg twice a day for my depression and to quit smoking. Everything was getting better. I had a great night's sleep. By day 2, I felt a little lighter with my mood. Then, on day 4, I felt wrong, and by my nighttime dose, I ended up having a seizure, which I have no history of. Again, no sleep, and tremors, and horrible sweating. I was really hoping this was going to help me, but I have never been so scared in my life as I was when I lost control of all my muscles, and it took 2 days to start to feel better from it. My muscles hurt, extreme anxiety, and insomnia. Be very careful with this drug!"

2 / 10
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  • Ske...
  • March 10, 2009

"Good for depression, not for anxiety/depression. I had a history of General Anxiety, it got worse after menopause. I was on different SSRIs, the side effects were awful. When my depression returned, my doctor had me try Wellbutrin SR. It caused agitation, loss of appetite, muscle tremors, and sleep disturbances, which were the worst. It does not help my anxiety, but it did help my depression. I am off it now to try something else in a week."

5 / 10
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  • Bon...
  • Taken for 6 months to 1 year
  • July 28, 2022

"I started on Zoloft for depression. Worked wonders, but I had difficulty reaching orgasm and next to no sex drive. Doc prescribed Wellbutrin, and it helped, but I was still experiencing sexual dysfunction. I had no trouble reaching orgasm, but it felt like nothing. There was a buildup, but no fireworks. Just a faint sense of relief from tension. I was cycled through buspirone, Remeron, and Trintellix before I gave up on SSRIs altogether. It's been two months on just Wellbutrin, and orgasms have gotten better, but they're still not what they were before medication. I'm going to continue taking it, but I'm concerned about the lasting effects from the SSRIs."

8 / 10
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  • Nic...
  • Taken for less than 1 month
  • January 17, 2017

"Started taking this for depression when I was 17 (16 years ago). After about a week, I had a massive panic attack that lasted for 2 days straight, and I've had a panic disorder ever since. Medication destroyed my life."

1 / 10
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32 Report
  • Mel...
  • Taken for 10 years or more
  • April 4, 2020

"I have been taking it for over 15 years, it has saved my life."

10 / 10
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72 Report
  • Ros...
  • Taken for 1 to 6 months
  • February 24, 2015

"Major change in my mood and energy. I enjoy doing things I used to do. Wellbutrin has changed my life."

10 / 10
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116 Report
  • Mam...
  • Taken for 1 to 6 months
  • December 9, 2018

"I have found this medicine to be very good for me. I'm taking 150 mg three times a day. It has also helped me with losing some weight. My Klonopin works well with it."

10 / 10
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40 Report
  • Anonymous
  • January 19, 2009

"I have been taking Wellbutrin SR to treat stress-related depression. I have had no side effects and have experienced a large increase in my libido. I feel like a kid again."

10 / 10
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77 Report
  • jay...
  • Taken for 6 months to 1 year
  • November 20, 2014

"Extreme dry mouth. Could not leave home without a bottle of water. Extreme dry stools to the point that I was taking a stool softener every day to avoid unnecessary straining."

3 / 10
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45 Report
  • Ht1...
  • Taken for 1 to 6 months
  • August 10, 2018

"Switched to Wellbutrin after being on Zoloft for two years, and it has been awful. I suffer from depression, PTSD, and anxiety. Wellbutrin has made me extremely irritable, and I'm constantly tired."

1 / 10
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23 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.