Bupropion and Anger: What Users Say (Page 5)

• Ive...
• Taken for less than 1 month
• December 10, 2016

Bupropion for Depression "I've taken it for a week now, and all it's caused was me and my gf to have big fights in public. I already had anger issues. It's worse now. I'll stick with it for another week or two, if it doesn't get better, I'm quitting this mess."

• Chi...
• Taken for 1 to 6 months
• September 3, 2013

For Depression "I have been taking bupropion for about 2 months. So far, I haven't noticed any drastic changes other than I've lost 10 lbs, lack of appetite, more energy, heart does race a little. I have, although, noticed at times feeling very angry at things that wouldn't have bothered me before. I do like the weight loss part, though I have to admit!"

• Dep...
• May 22, 2017

For Depression "My doctor switched me from Prozac, which I have been on for years and really works for me. The reason for the change was lack of sex drive. When taking this medication, I became anxious and angry. My heart would palpitate, and I would shake. Stopped taking and went back to Prozac and leaving good enough alone. This was scary stuff."

• Cat...
• Taken for 1 to 6 months
• April 22, 2015

For Bipolar Disorder "I was started on Wellbutrin about 2 months ago, along with Lamictal for mood stabilization. I reluctantly got on it after a year free of meds (when I got hit with a bad case of Seasonal Depression beginning in fall and lasting through March and some of April, after a move to mostly gloomy Asheville, NC). I started off on half a tablet of 75 mg regular release. Then I went up an extra half a tab. At first, I thought it was great, and then I started to feel low down again and went up to 150 mg. Slowly, I noticed feeling quite agitated and almost aggressive. I cut back down to just one tab and then half a tab, and still the side effects persisted, along with horrible anxiety and restlessness. So no more for me."

• Che...
• Taken for 1 to 6 months
• March 21, 2017

For Depression "When I was taking this just as a smoking cessation aid, I couldn't sleep ever. Not even when I took half the prescribed dose and took it early in the morning. It made me crash, made me irritable, and couldn't eat. But now I take it for Major Depressive Disorder and as smoking cessation, and even on 2 tablets (300 mg total) I fall asleep! And not at night time...it makes me fall asleep during the day, especially after it kicks in. I can take it at 5 pm and fall asleep at midnight or even before, take naps, etc. This is the only antidepressant I will take, because SSRIs do not work one bit for me. They make me feel more depressed. Wellbutrin does help my moods, though. I don't get fits of rage when I take this anymore like I used to."

• Som...
• Taken for 6 months to 1 year
• March 26, 2021

For Major Depressive Disorder "My condition is major depression, anxiety, and PTSD. Been taking this drug for 7 months now, and it didn't help me at all. For about 2 weeks, I was feeling better, and a little bit of my sex drive was back. After that, everything was back to how it has been for the past 20 years. No motivation, sadness, anger, and I don't have ANY sex drive. Even doubling the dose (from 150 mg to 300 mg) didn't help. I am still taking this pill, working out every day and doing yoga and all the stuff, but these days I even feel worse than ever."

• Ann...
• December 22, 2020

For Depression "I was on Wellbutrin for 5 days before I had to stop. What I was feeling went way beyond normal side effects. Mentally, I was having a complete breakdown. Sobbing for hours, having thoughts about self-harm. Stuff I hadn't ever thought about before. My depression wasn't that bad prior to Wellbutrin, it mostly manifested in having low energy/motivation, but I wasn't 'sad'. Now, all of a sudden, I am bawling my eyes out, and I have no idea why. This would morph into extreme anger, again not for any real reason. I was forgetting simple words, losing my train of thought, and unable to hold a conversation. Physically, I was feeling brain zaps and waves of uncomfortable tickles, tingles, pins and needles washing over my skin. I couldn't move my eyes side to side, it would trigger a reaction where my brain would shake and chills would go down my spine. My balance was off, and I couldn't sleep, I just laid in bed crying and twitching. 2 days after I stopped taking this, I felt okay again."

• aor...
• Taken for 1 to 6 months
• September 7, 2021

For Depression "Two years ago, I was a 33-year-old woman who took 150 mg of bupropion daily for a little over two months. It was the only medication that I was on at the time. My partner and I noticed that gradually, I lost my sense of fear. As in, I was no longer afraid of anything. Instead, I began to show signs of immediate aggression the moment something irritated me. Example: while waiting for a doctor's appointment with my partner, an older man went up to the receptionist area and started yelling and berating them out of nowhere. Typically, I'm a 'freeze' type of person, who blanks out when confrontations or anxiety-producing situations occur. Not this time. Without thinking, I got up with my fists balled and was getting ready to punch him in the face. My partner had to grab my wrists and drag me back into a chair and keep me down. That situation was enough to have me come off the medication. Can't say I don't miss that effect at times, though."

• wil...
• September 4, 2015

For Depression "After years on Prozac, switched to Wellbutrin XL 150 mg 5 days ago. I had gained at least 40 pounds while on Prozac. On day 5 of Wellbutrin XL 100 mg and so far, so good. I am waking up throughout the night, no appetite, which isn't a bad thing - down 4 pounds already - much more energy - however, I am finding my OCD tendencies are getting stronger and things that I would let go, a couple of nights, kept waking up throughout the night. But appetite - no appetite - down 4 pounds. Do find that some of my OCD issues are stronger than they were before...not too bad, so hopefully things will settle down on that front, and the anger issues where I am angry at anyone and everything will settle down also."

• pan...
• Taken for 1 to 6 months
• March 17, 2021

For Smoking Cessation "I'm also on Pristiq for depression and recently put on 300 mg Wellbutrin to quit smoking. I've been on it a month now, and I've never felt worse in my life. I thought I was going crazy, I've been crying, shaking, migraines, ears ringing loud, then pressure in my head, heart palpitations very often, forgetting things, bad dreams, insomnia, angry, no appetite, dry mouth, everything tastes awful, itching, having thoughts about suicide. I broke down today and told my husband the details. We looked things up, and he says it's the medicine. I hope so, my mind is a prison. I can't escape the negative thoughts, and this just isn't me. This is the most horrific medicine. I've never left a comment, nor have I had any reactions to any meds. I suggest you know yourself very well, mental cycles, and body before taking. Today is my first day not taking it, and I'm still a mess."

• tyh...
• June 26, 2021

For Major Depressive Disorder "Was prescribed this for depression and possible ADHD. I was optimistic since the med worked really well for my dad. After around 4 weeks of waiting, it did start having an effect... of an unwanted quality. I was tense and anxious all day long and seemingly only had energy for being that way. I also started being angry, which is normally 100% out of character for me! I'd snap at everyone who tried to talk to me, throw and break things, and hurt myself. Super scary and I didn't see a positive effect. Had better luck with an SNRI since I've got anxiety as well. So be careful if you're anxious."

• Not...
• July 11, 2011

Bupropion for Depression "I'm shocked to see not a single negative review listed. The first day taking Wellbutrin after drinks with a friend (not advisable), we had a bad fight, my anger was uncontrollable. The next day, I had a fight with my roommate, I was absorbed in rage, completely unaware of others' feelings. That week, I was stuck in my head, angry, charged, paranoid, and isolated. A week later, I had a terrible fight with my roommate resulting in a bad physical altercation, cops were called, and the next day she moved out. The next day, I was extremely depressed and indifferent. I stopped taking it. Maybe I didn't give it time. Don't want to discourage others, but if you have irritability/anger issues, be very aware and cautious."

• Jan...
• Taken for less than 1 month
• June 23, 2018

For Depression "I have BPD. I suffer trauma from my childhood. Anyways, I was looking desperately for a med to be a type of mood stabilizer. This medication did not work for me one bit. I went on it for two weeks, and I BROKE OUT in cystic acne and got geographic tongue. These things are not serious, but it was enough for me to quit. I also had my first gout attack, all after Wellbutrin 150 XL. I know these may contribute from other factors, but I live a healthy and active lifestyle. Otherwise, I am female and only 27. Going back on Trintellix. If anyone is looking for a medication that doesn't interfere with your sex drive, Trintellix is it. Expensive, but well worth it. I am currently on the 5 and will be increasing to the 10. I am not worried, as those who reported a decrease in sex drive were nearly the same as placebo in studies. Wellbutrin is not worth it, it is complete garbage. It made me very angry and hostile, got nothing done during the day, and I wonder why. I was an angry psychopath on Wellbutrin. Never again."

• Jos...
• Taken for 1 to 6 months
• June 15, 2022

For Depression "I tried Bupropion/Wellbutrin since I didn't react well to SSRIs/SSNRIs. I can tell the first 4 weeks was pure nightmare: no sleep, no appetite, panic attacks, terrible anxiety, feeling sick all day. But after that, it became much better. Suddenly I started to notice that I had a lot more energy, I had more self-confidence, my social anxiety was better, so I got back most of my motivation and old life. And... most importantly, instead of the lack of libido, I had increased sex drive! So far, perfect, right? Well, unfortunately not really, but overall it is indeed a good medicine. The reason why I decided to stop taking it after 3 months was that some of the stubborn side effects stayed: after months I still couldn't fall asleep, I was drastically losing weight, I became aggressive and sometimes paranoid, and my anxiety showed only minor improvements. If you have anxiety, forget it, for depression, it is worth a try, but there is a reason that this is the last medicine you are prescribed."

• Bor...
• Taken for less than 1 month
• December 17, 2019

For Depression "I was on Zoloft for three months and gained 15 lbs even though I work out and lift every day. This sucked because it really made me feel mentally better. My doctor then put me on Wellbutrin (bupropion), and the first day I felt okay, but now I am into day six, and I wouldn't wish this onto my worst enemy. I cry uncontrollably, I am angry, I am dizzy, I can't focus, and when I move my eyes from side to side, I feel like I am going to pass out. I am stopping it today. I was reading these other reviews, and I am glad to know I am not crazy - this drug should be taken off the market."

• Car...
• February 28, 2021

Bupropion "I only took this for three days because it increased my anxiety greatly and did not help with the jaw clenching I’ve been experiencing. It also made me incredibly and irrationally angry about everything, and I felt like I was crawling out of my skin. This was only on 50 mg, which is half the starting dose."

• Lee...
• April 30, 2021

For Depression "I started bupropion 150 mg XL 1x daily 6 weeks ago. I have depression, general anxiety, social anxiety, and PTSD. Week 1, I felt like I was on cocaine. I was restless, angry, and crawling out of my skin. I could not eat. Mind you, I usually eat a lot. I’m about 40 lbs overweight for reference. (I’ve lost 10 lbs in the 6 weeks since I’ve started this.) In these past few weeks, the stimulant effect has kind of evened out, and now I feel what I can only assume is “normal.” I don’t have to force myself to get up in the morning and clean my house and go to work. I don’t have to hype myself up for 3 hours to make one phone call. (It has helped my social anxiety remarkably.) I do want to mention that in the last couple of weeks, I have been showing signs of some new and unusual OCD tendencies, and I’m assuming it’s the medication. I haven’t noticed any other side effects except the stimulant effects in the beginning. All in all, this has really helped me so far."

• Ble...
• Taken for 6 months to 1 year
• June 13, 2016

Bupropion for Major Depressive Disorder "Brand name Wellbutrin XL 450, severe gain weight, severe anger, severe stomach pain, severe constipation, severe vivid nightmares, made me from social normal person to an unreal horror human, scared to the world.... More than 90 days I can't even get out of my room.... severe panic attacks!!!"

• 229...
• Taken for less than 1 month
• October 22, 2021

Bupropion "My psychiatrist decided to start with bupropion SR for my ADHD because it was less addictive than the usual ADHD meds. Of course, I was open to this because I just wanted help. I have been on bupropion for 3 weeks now, and it has been, emotionally, the worst 3 weeks of my life. I would say that typically I am a happy person, and I don't ever have a hard time controlling my emotions, but on bupropion, I've done a 180. I cry throughout the day, some days I can't get out of bed, I find myself getting extremely angry over the smallest things, and to top it off, I am less focused than I was before because of these emotional episodes. Overall, I would say that I don't really understand why it was prescribed for ADHD. If you have depression and ADHD, then I think this MAY be a good fit for you, but if you just have ADHD, this may not be for you."

• xxy...
• Taken for less than 1 month
• March 21, 2022

For ADHD "After about a week on this, I had a complete mental breakdown. Hyperactive, sleeplessness, shaking, impulsive, irritable, racing thoughts, angry outbursts, threats of hurting others. Feeling of nausea and collapsed on the floor once. My family was so alarmed they had me dragged off to the hospital in the middle of the night."

• Muc...
• Taken for 1 to 2 years
• April 4, 2020

Bupropion for Major Depressive Disorder "Please do not drink alcohol on this medication. It’s an amazing drug but if you drink on it, it’ll make you angry and paranoid. I did just that and I lost all of my friends and family."

• zoo...
• November 26, 2014

Bupropion for Depression "Bad for me. Would not let me sleep. Felt angry all the time. Did not help me at all, in fact, it made things worse."

• tom...
• Taken for 1 to 6 months
• February 25, 2019

Bupropion for Depression "Good for fatigue and anxiety with social phobia. But memory problems, aggressiveness, increased appetite, and hypertension were major issues. No improvement in depression whatsoever. Took 150 mg."

• AMA...
• Taken for 1 to 6 months
• December 19, 2022

Bupropion for Major Depressive Disorder "Never worked. It actually made me feel worse and more depressed. I didn’t realize it was the reason for being so rude and aggressive for no reason until it became very clear."

• Anonymous
• January 12, 2012

For Bipolar Disorder "I'm not sure yet what to think. I've been on 300 mg of Bupropion XL for one week and feel angry, edgy, and cranky."