Bupropion for Major Depressive Disorder User Reviews (Page 4)

• Lor...
• Taken for less than 1 month
• April 15, 2023

Bupropion "I'm a 52-year-old male that has suffered with long-term depression for the majority of my young and adult life. I came to terms with the fact that I must medicate in order to have a fighting chance. I called my doctor a few days ago, and she recommended Wellbutrin based on my constant suicidal thoughts and battle with anxiety and depression. I was excited at the thought of 'turning the page' of my life. I must say that I was absolutely surprised at how well and how fast Wellbutrin worked. I just can't express what a difference it's made in my personal life. Now I have a good chance of mending fences with family that I once ignored purposely due to my severe battle with depression. Only time will tell just how good Wellbutrin works - it's a beautiful start, though! Wishing you all peace in your journey."

• Clo...
• August 13, 2015

Bupropion "Struggled with MDD and Gen. Anxiety Dis. and self-harming habits. Wellbutrin has changed my life. It's definitely a noticeable chemical adjustment for the first few weeks. Once I adjusted though, it was a miracle. I'm calm, don't have anger or outbursts, no anxiety, no obsessive thoughts or ruminating. I haven't been depressed in over 3 months and I started Wellbutrin in Feb. of 2015. I've had no side effects besides the first few weeks. You will feel very weird for two weeks. Stick with it. No weight fluctuations, dry mouth went away, no sexual side effects, and I have more energy but I don't feel artificially stimulated (you will for about a month though). I give this medicine a 10. My doctor says I'm textbook MDD. Runs heavy in my family."

• Ann...
• Taken for 1 to 6 months
• April 15, 2020

Bupropion "I started Wellbutrin after taking Zoloft for about 6 months but had to stop because I gained 30 lbs in 3 months and was retaining water like crazy. Wellbutrin definitely stopped the water retention, and I’ve lost about 6 pounds since starting it about a month ago. Unfortunately, I have to stop taking this one too. I was hoping this would be the one— I’ve been back and forth on a lot of meds, but nothing has worked. I felt severely angry and would lash out. I’ve never been that way. I am convinced this medication has caused me to have anger problems when I never had them before. Coming off the medication hasn’t been great, super emotional, tired, lots of headaches, and irritability, but after day 12, I’m finally feeling better."

• ctr...
• Taken for 1 to 6 months
• February 4, 2020

Bupropion "After 1 week of taking Wellbutrin, I developed severe intrusive tinnitus. I have been off the drug for almost a year, and it has not faded at all. While obviously this side effect doesn't happen to everyone who takes Wellbutrin, it is frighteningly common. All of the doctors I've seen since then (psychs, ENTs, etc.) weren't surprised at all when I told them my tinnitus was from Wellbutrin. It has absolutely destroyed what was left of my life. I already had depression, anxiety, and insomnia, now all of these are 100x worse, plus suicidal thoughts. Again, I don't want to say 'don't take this drug' because all drugs have side effects, and I was one of the unlucky ones. But I would highly suggest something else as I would not wish this on my worst enemy."

• Ano...
• Taken for 2 to 5 years
• May 16, 2020

Bupropion "I have suffered a lot from MDD and Panic Disorder. My primary doctor prescribed Wellbutrin for me, and it did absolute wonders for my depression, but my panic went up by tons. I had panic attacks for no reason, every single day. I was later added to another SNRI along with a decreased dose of the Wellbutrin. After that, my anxiety became much more manageable. If you suffer from anxiety as well as depression, please talk to your doctor/psychiatrist about taking Wellbutrin with another medication."

• Jam...
• Taken for less than 1 month
• August 23, 2017

Bupropion "So I was on Lexapro 20 mg for 3 months, and it helped somewhat with my very severe depression that I was suffering from with severe anxiety. It was hell! So, at my next appointment with the nurse practitioner, I was prescribed bupropion XL, and she told me to add it to my Lexapro and to take both together. But as soon as I started to take them both, I got very emotionally sad and numb. So my sister told me to stop taking the Lexapro to give the bupropion a chance to work on its own, and that has helped so much because now I feel a lot better than before, and I'm only taking 150 mg XL. Just wanted to share my experience with anyone."

• Tac...
• Taken for 1 to 6 months
• November 24, 2019

Bupropion "I started this a month ago, first, it made me very hostile, but after a few days, I evened out. I am taking it having bulimia and anorexia alternating, as well as major depressive disorder. It has actually helped me control my eating and almost fully stopped the binge-purge cycle. However, it does have its drawbacks. I have a fast heart rate, not really fast but noticeable, less suicidal thoughts, but when they do come, they are stronger impulses. The urge to self-harm has been lowered, but I still have moments I lose control. It has definitely helped me a lot, and I choose the side effects over wanting to commit suicide constantly. This has saved my life 100% for sure because before, I had planned to end my life, but this made me reconsider it, and I want to live."

• Srw...
• Taken for 2 to 5 years
• October 14, 2015

Bupropion "A noticeable difference between the brand and generic (bupropion). Started out with brand years ago. I was no longer stuck in bed avoiding life. I could concentrate, no impulsive decision-making or stuck with indecision. Interested in life again, getting out, and lost 40 lbs within the first year. Then insurance changes meant getting generic. I thought, 'no big deal, I take generic for everything'. I soon found myself overpowered by MDD symptoms again while still taking an AD. Dr. mentioned switching to generic was likely the problem. I've since found lots of FDA/med research/similar experiences. Thankfully, I'm back on brand doing good, it wasn't just all in my head. There really is a BIG difference."

• Fox...
• Taken for 6 months to 1 year
• February 1, 2024

"I was a full-blown alcoholic and drank rum and whiskey every night with thoughts of an abusive childhood for me and my brother. Then my brother passed at the age of 42 and left me alone with all the darkness we went through together. I felt I was alone in there now, and no one was with me. I had a few mental breakdowns, and I was sober for over a year, but I was in a dark place, and I feared my wife would soon leave me. Then the doc put me on these at 150 mg, I didn’t want higher. I told him I was in them for about 3 weeks or a little more, then I had another bad episode. Then they started to work, it just took a while. I see things differently now. I see the way the leaves blow in the wind on the trees, I hear the beauty and see the beauty of everything. My eyes are open now, and I crawled out of that dark hole and thinking about a better career change, financially, in which I was always too scared to do in the past. These pills saved my life and my family."

• Mac...
• December 11, 2019

Bupropion "I started taking 150 mg about two years ago, quickly went up to 300 mg. My motivation went back to a normal level, and I started painting, drawing, and cooking again. My only issue was that I started getting daily headaches (after I had been on it for six months). My doctor put me on 150 mg, which got rid of the headaches, but my motivation got worse. I felt like I could do things I couldn’t when depressed, but also like I needed to convince myself to do anything extra. My doctor then gave me 5 mg of Lexapro on top of the Wellbutrin, and it’s good. Recently got my blood work done for being fatigued, sleeping a lot, and brain cloudiness - it’s because I have a severe vitamin D deficiency. I highly recommend getting your blood work done if you feel like this suddenly loses effectiveness. A low vitamin D level can also cause depression, which probably made it harder for me to feel better even on medications. Also, look into getting this prescription from Walmart, it is apparently $9."

• Ami...
• December 25, 2016

Bupropion "Wellbutrin XL (Bupropion) has helped me kick cravings for alcohol and other drugs. It's really amazing. My doctor prescribed it for major depressive disorder/PTSD, and I can feel it helping me get through the winter. I started out on 150 mg for 2 months, which was fine, then one month on 300 mg, which was too much (everyday stomach aches, shakes, too much energy, very speedy), so the doctor put me back on 150 mg XL, which is again working nicely, and all the shaky/speedy feelings I had on 300 mg are gone. My first 2-3 months on this drug, I didn't have much of an appetite, but it came back after that, so now I still eat normally even though I'm on the drug. So yeah, it takes some getting used to. Don't expect immediate results."

• Jan...
• Taken for 1 to 6 months
• December 20, 2020

Bupropion "Wellbutrin worked for me, was actually pretty much a lifesaver. Tried Zoloft and Buspar and Effexor, all didn't work too well. However, this med does have side effects like increased anxiety, but apart from that, I haven't experienced much else. It calms me down and makes me feel like the old me when I was a kid. Confident and happy."

• rr8...
• Taken for 1 to 2 years
• February 17, 2016

Bupropion "For the past five years, I have been battling depression. I feel extremely fatigued and unmotivated, with thoughts of wanting to be dead. Life is totally miserable most times. I went from Cymbalta to Wellbutrin, and after a few weeks, I started to feel alive again. After about a year on it, now I am back to my old depressive ways, and my doctor is reluctant to start me on something new. So right now, I am miserable again and waiting for my doctor to try something different. I wish all the best to everyone out there fighting this terrible disease!"

• Squ...
• Taken for 1 to 6 months
• March 21, 2023

Bupropion "I was so depressed for several years that I could no longer manage my own hygiene, cooking, cleaning, or even leaving my apartment. I tried multiple antidepressants and mood stabilizers, nothing worked. Then I was put on Wellbutrin XL, and two months later, my hygiene is managed, I've lost 20 kg, and am no longer obese. I am outside again and even using public transport. I had no light left in my life, and I was planning to end it. This medication saved my life."

• Gog...
• Taken for less than 1 month
• May 17, 2019

Bupropion "I have only been on bupropion XL for 2 and a half weeks. I'm on it for MDD. But that being said, I can see it starting to work. I am not as anxious as I normally am. My thoughts seem more rational and aren't spiraling out of control like they normally do. I was on Celexa for years but found it wasn't working, and climaxing was such a struggle to achieve. My female libido is really coming back to what it was 20 years ago! I really am excited that I am starting to feel more happy and not so easily irritated. Give it a try if you are struggling. I'm sure it's not for everyone, but you won't know until you try :)"

• KMD...
• Taken for 1 to 6 months
• March 7, 2017

Bupropion "I was on the 75 mg SR formulation for a week before taking two a day. Went to 150 XL the next month and 300 XL after that. I've been on it for about three months now. I love this medication. It's changed my life. I don't feel depressed very often anymore, and combined with therapy, my life is substantially better. No side effects at all! Much better than Lexapro, which gave me bad sexual side effects."

• col...
• Taken for 6 months to 1 year
• December 22, 2022

Bupropion "Though I was struggling with an intense chemical imbalance (feeling incredibly hopeless/empty/anxious), I avoided meds for a long time, terrified by bad reviews until the amount I struggled through every waking moment of my day made it impossible for me to continue avoiding. Started on 100 mg of bupropion. I remember feeling very weird at first, dissociating on the first day, then sweating, heart palpitations, some anxiety, and my leg randomly shaking (nothing unmanageable). Immediately, depressive feelings were greatly alleviated. Then a month in, all initial symptoms were pretty much gone, though I still had pockets of depression, so I upped my dose to 150 mg XL. Miraculous. I now feel calm, collected, and very content and thankful for my life. The only side effects I still feel are some ear ringing and loss of appetite (not complaining). This was the extra boost of dopamine my brain needed to function like a normal, healthy human brain. Absolutely incredible and so thankful this exists!!"

• dep...
• Taken for 1 to 2 years
• May 9, 2015

Bupropion "I got to a point where I was in bed 20 hours a day, couldn't work, etc. Severely depressed. I've battled that all my life but never got on an antidepressant. Wellbutrin, along with Lexapro 20 mg, changed my life. Mainly the Wellbutrin, as I truly changed when that was added. I'm on 300 mg SR. At first, you'll feel jumpy and anxious, but give it 3-4 days, a week tops, and it'll be incredible. I have a new job, I'm traveling. New person."

• Mel...
• Taken for 2 to 5 years
• February 2, 2016

Bupropion "I highly recommend Wellbutrin XL. I used to suffer from major depression, but thanks to Wellbutrin, my depression is almost nonexistent. Another great thing about it is that I don't have any side effects. In the beginning, I lost my appetite, and everything tasted bland. I was fine with that because I wanted to lose some weight, but thanks to my other medications, my appetite came back. Darn! Maybe if you take it and want to lose weight, you will get lucky as long as you don't take other medications to counteract it."

• Blu...
• Taken for 6 months to 1 year
• July 11, 2019

Bupropion "I have been on 300 mg Wellbutrin (WB) for 6 months. I was in a deep depression, and WB gave me the drive to get out of bed and out of the house. The physical symptoms of depression were greatly reduced - more awake, alert, increased sex drive, normalized cognitive function. However, it made me feel very uncomfortable - wound up, agitated, irritable. I didn’t like the person I had become. It was almost as if my ego had been amplified tenfold. I reduced to 150 mg and felt immediate relief from the restless energy, which was worsening my emotional state. I am considering discontinuing."

• Coc...
• Taken for 5 to 10 years
• May 23, 2017

Bupropion "Suffered three mental breakdowns, hospitalized three times & off work each time four months each. I am on Wellbutrin XL 300mg once daily in the a.m. and find I can function fully during each day; also take 'Adco-Alzam' 0.5mg twice daily to suppress panic attacks. Been on this for >8 years; and have got my confidence back!! Symptoms UNDER CONTROL!!! At last confidence and quality of life, not going off these again.... NEVER!"

• Don...
• October 4, 2014

Bupropion "I've been taking 150 mg for 2 weeks now. I felt the effects in just a few days. I have a lot of energy, and it has increased my thirst. I've lost a few pounds. My only problem is sleep. I've been taking zolpidem for 3 years (5 mg) and it isn't helping much. I've taken a few other antidepressants in the past, and this has been the most effective."

• Lin...
• October 4, 2014

Bupropion "I just started taking this after being almost debilitated by mirtazapine. I don't know if for sure I have an energy increase because of the Wellbutrin or because I quit taking mirtazapine. At any rate, I do feel better overall."

• Suu...
• November 13, 2015

Bupropion "I have bipolar disorder, anxiety, severe depression, PTSD, and an eating disorder. I am a 25-year-old female, and I've been taking Wellbutrin for 3 days with Lexapro. I've tried them all: Lamictal, Abilify, I don't need to go on. My doctor put me on this after attempting suicide. I'm trying this before I go to my last option, hospitalization. I've read so many positive comments, and I feel a difference already. I have so much energy, but I'm still sleeping a lot. The migraines are horrible, but that's really nothing new with this type of medication. This will be the 7th trial of medications I've been on in a year. Not one has worked. I'm trying really hard and being very patient. I hope for a happy ending, like most of you."

• San...
• Taken for less than 1 month
• July 20, 2019

Bupropion "My psychiatrist put me on Wellbutrin 75 mg once a day to start with, and after 7 days I went up to 2 times a day. Before I started to take it, I couldn’t get out of bed because of my depression. My energy levels were at almost zero. The Wellbutrin has helped me tremendously. I actually have energy to get out of bed and live my life. The side effects are constipation and loss of appetite. In the past, it gave me severe anxiety, which is why my psychiatrist started me at a very low dose, and it’s actually helped."