Brimonidine / brinzolamide ophthalmic and Drowsiness: What Users Say

• Kar...
• July 25, 2013

Brimonidine / brinzolamide ophthalmic for Intraocular Hypertension "Very effective in decreasing eye pressure from 34 to 19 in one week. Side effects started increasing at two weeks, including blurriness, eye discomfort, drowsiness, and syncope. I am stopping Simbrinza on day 15."

• Chu...
• Taken for 1 to 6 months
• January 20, 2020

Brimonidine / brinzolamide ophthalmic for Intraocular Hypertension "This is an addendum to the review I wrote on 12/15/19: The feeling of fatigue and drowsiness after applying Simbrinza is consistent and may even have gotten a bit more intense. I also discovered that this drug drops my blood pressure by 20-30 points systolic and 5-10 points diastolic for about 2-3 hours after applying the drops. Not a big problem for me, as my 'normal' blood pressure is a little on the high side. If you normally have low blood pressure, be aware of this."

• Ano...
• Taken for 5 to 10 years
• May 10, 2025

For Glaucoma, Open Angle "I was given this drop by my eye doctor a long time ago, and I know it has done what he wanted it to do for my glaucoma. My only problem is that it makes me so drowsy that sometimes I find myself on the couch asleep just a couple of hours after getting up and taking the eye drop. Is there another that does the same thing but won't make me tired? Or can a stronger dose of this drop be taken at night only?"

• Bli...
• Taken for 6 months to 1 year
• August 10, 2018

Brimonidine / brinzolamide ophthalmic for Glaucoma, Open Angle "I take this for glaucoma. Effective at lessening ocular pressure. Makes me drowsy, so I take it at bedtime."