Brimonidine / Brinzolamide Ophthalmic Dosage
Medically reviewed by Drugs.com. Last updated on Aug 26, 2024.
Applies to the following strengths: 0.2%-1%
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Intraocular Hypertension
1 drop in the affected eye(s) 3 times per day
Comments:
- This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Usual Adult Dose for Glaucoma (Open Angle)
1 drop in the affected eye(s) 3 times per day
Comments:
- This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Usual Pediatric Dose for Intraocular Hypertension
2 years or older:
1 drop in the affected eye(s) 3 times per day
Comments:
- This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Usual Pediatric Dose for Glaucoma (Open Angle)
2 years or older:
1 drop in the affected eye(s) 3 times per day
Comments:
- This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.
- If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Renal Dose Adjustments
Severe renal impairment (CrCl less than 30 mL/min): Not recommended
Liver Dose Adjustments
Severe hepatic impairment: Use with caution
Precautions
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug is for topical use only and it is not for injection or oral ingestion.
- Shake well before use.
Patient advice:
- Pressure should be applied to the tear duct immediately following administration of the drug.
- To avoid contamination of the solution, the container should be kept tightly closed.
More about brimonidine / brinzolamide ophthalmic
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- During pregnancy
- Drug class: ophthalmic glaucoma agents
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Patient resources
- Brimonidine and brinzolamide ophthalmic drug information
- Brimonidine and brinzolamide (Advanced Reading)
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.