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Aspirin and Upset Stomach: What Users Say

Brand names: Acetylsalicylic Acid, Ecotrin, Vazalore, Bayer Aspirin, Arthritis Pain, Easprin, Aspir-Low, Aspi-Cor, Aspergum, Aspir 81, Aspirtab, Ascriptin, Empirin, Bayer Aspirin Extra Strength Plus, Ecpirin, Entercote, Halfprin, Ecotrin Adult Low Strength, Genacote, Bufferin, Norwich Aspirin, Aspirin Low Strength, Bayer Aspirin with Heart Advantage, Fasprin, Acuprin 81, Arthritis Foundation Pain Reliever, Buffered Aspirin, Durlaza, Extra Strength Bayer, Ascriptin Enteric, Heartline, Ascriptin Maximum Strength, Bufferin Low Dose, Medi-Seltzer, St. Joseph 81 mg Chewable Aspirin, Aspiritab, Bayer Children's Aspirin, Buffex, Ecotrin Maximum Strength, Gennin-FC, Genprin, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, St. Joseph 81 mg Aspirin Enteric Safety-Coated Bayer Women's Aspirin With Calcium Miniprin Aspirin Lite Coat Bayer Aspirin Regimen Migralex Bayer Advanced Aspirin Buffasal …show all brand names

Upset stomach: mentioned by 3 users (5.8%)

Based on user experiences from 52 Aspirin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bleeding 5.8%
ulcers 5.8%
upset stomach 5.8%

Reviews for Aspirin

Commonly mentioned side effects
  • Mar...
  • August 17, 2009

For Sciatica "I am a 35-year-old male with moderate to severe sciatica (pain from buttock to ankle) due to a bulging disc L5 - S1. I found taking a 1000 mg dose gave significant and almost total relief for about 1 to 2 hours. The effect was greater if the pain was not too severe, the best results came from taking aspirin before the pain got severe. I also found that taking aspirin without food made it work faster, but I suffered stomach aches as a consequence."

7 / 10
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58 Report
  • Ior...
  • Taken for 10 years or more
  • November 16, 2017

For Osteoarthritis "Aspirin suits me best because I do not suffer from H. pylori, otherwise, it may cause ulcers, although lansoprazole or omeprazole can prevent the stomach issues. The reason that aspirin is best is that it helps, along with vitamin C and omega-3, to lubricate the joints, which is essential for painless movement. I sometimes interchange with ibuprofen, which, because it is coated, lasts longer than aspirin, but I have no knowledge of naproxen."

8 / 10
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5 Report
  • ano...
  • Taken for 1 to 2 years
  • September 13, 2025

For Angina "I have used Azpamin and it works very well for me but it causes stomach cramps and ulcers."

6 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.