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Amitriptyline for Depression User Reviews (Page 5)

Reviews for Amitriptyline

Commonly mentioned side effects
  • Not...
  • Taken for 1 to 6 months
  • October 31, 2021

"I have suffered from depression and anxiety for almost 27 years. Amitriptyline was another medication that didn't help at all. After five months, I decided to quit taking it. The dose was 200 mg at the end of that period, so it was maximum."

1 / 10
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  • tes...
  • Taken for 1 to 6 months
  • March 2, 2021

"Took Zoloft (Sertraline) for social anxiety for 3 years. Feelings were too numbing, couldn't even cry when I wanted... not natural. Doc put me on 50 mg of amitriptyline at first, but the dose resulted in severe constipation. So reduced to 25 mg at bedtime, and stool softener, more water, fiber, and workouts 2 or 3 days a week. If you're taking iron, it may cause moderate constipation, be aware it could possibly make bowel movements difficult."

7 / 10
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  • Bun...
  • Taken for 10 years or more
  • July 18, 2021

"I was on amitriptyline for well over 25 years for various conditions, including depression. I decided to slowly withdraw myself over 6 months. The most I ever took was 45 mg nightly. THIS IS A WARNING TO EVERYONE: Make darn sure that you intend to stay on this drug because the withdrawal is horrendous. I have been off it for 8 weeks, and it is pure nightmare material: insomnia, aches, bloating, panic attacks, etc. I am struggling and wish I had never heard of this drug. I believe it is addicting. Yes, it helped me, that is why I am warning users of this medication to be very careful because going off/staying off is the most nightmarish time you will ever have. Good luck."

2 / 10
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Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • August 10, 2021

"I have been on Prozac for depression and anxiety for a month, but I had to stop because the insomnia got worse. Then I saw another doctor who prescribed this drug, amitriptyline. I started with 25 mg at night, then increased to 50 mg. Anxiety and depression gone. Sleepless nights gone. But I have dry mouth, surprisingly only during the day when I'm outdoors, and also weird dreams. I am looking forward to going back to 25 mg as a maintenance dose to see if the dry mouth will go since it wasn't there at 25 mg. It helps!"

9 / 10
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  • cam...
  • Taken for less than 1 month
  • July 26, 2014

"I'm taking this more as a mood stabilizer. The medicine has caused my tongue to be sore, excessive dry lips, mouth, and throat. It has helped with my mood, though. I can't take this medicine anymore. I'm contacting my doctor for some other medication."

5 / 10
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  • Pk7...
  • Taken for 1 to 6 months
  • November 12, 2015

"Not recommending this. On 25 mg, knocked me out for 12 hours and groggy for the next 12 hours. Cut pill into quarters and still had a strong effect, causing grogginess all of the next day. Went to trazodone, which is perfect for me."

1 / 10
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  • jus...
  • Taken for 1 to 2 years
  • December 20, 2020

"Many years ago, I was taking amitriptyline, and I began randomly passing out, and when I fell down, seizures began. (I never had seizures before this.) Each time, I was taken to the emergency room and woke up confused, and in some cases, they told me I was still begging for help, even though I was begging the paramedics who were there to do just that. I didn't even realize that was who they were. It was very scary, and although the drug didn't cause the pain (that was the falling and hitting my head and/or face), it was painful. After five different trips over a year's time, I decided to get off the amitriptyline and never had another spell or seizure again."

4 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • January 20, 2018

"Was prescribed for bipolar depression. At first, it helped with insomnia (and relieved constipation!), which was a godsend, but faded after a few weeks. After 1 month, I had crippling fatigue, and it seriously jacked my heart rate up, so lowered from 75 to 50 mg. Spent another month developing akathisia before finally ditching it. I’m sure it’s great for some, but my body hated it. Not to mention it did squat for my mood."

1 / 10
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  • ran...
  • March 19, 2021

"It is the worst drug ever. Tryptomer I have been taking this for one month. Initially, it was 10 mg for 1 week, then 25 mg. This drug has made me more depressed. My neuropathic pain has also increased."

1 / 10
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  • Tir...
  • Taken for less than 1 month
  • April 9, 2022

"Well, I have only taken it for 2 nights as of today. The first night, I took around 50 mg, and I felt like I couldn’t get up for most of the day and was dizzy, so I halved my dose again for tonight. I have to say I’m a little scared of this medicine, but I have read some good reviews on this page, so I am going to keep taking it and see if some of the side effects let up. I was also pretty moody and feeling angry for the day, so I hope all this passes, from what I read, it will hopefully. I will post again in another week and tell my results, hopefully, they are good because I have tried everything for my depression and lack of motivation."

5 / 10
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  • Wen...
  • Taken for less than 1 month
  • August 14, 2019

Amitriptyline "I have been depressed for a very long time. I took everything, and nothing worked. My doctor gave me Elavil. I'm scared to take it. This whole summer, I never went out. All the things I used to love to do, I don't do them no more. I feel so alone. I don't know if I should try it. I never heard of it."

2 / 10
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  • Mol...
  • Taken for 1 to 6 months
  • October 20, 2018

"I was only on amitriptyline 25 mg for a few months, and I started waking up with pain and stiffness in the palms of my hands. I don’t know if it’s from the medication, but I stopped taking it, and I’m waiting to see if the pain and stiffness go away. Wondering if this has happened to anyone else?"

4 / 10
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  • Jom...
  • January 7, 2021

Amitriptyline "Elavil makes me poo my britches. I feel really good when I use it, but then out of nowhere, I poop my pants or sometimes I poop the bed in my sleep. This is embarrassing and frightening to experience. One night while on Elavil, I went dancing with some friends. I wore my favorite dance pants, which are a tight, stretchy material and very thin fabric. I refuse to wear underwear with these particular pants as I enjoy how they accentuate my, shall I say, “fruits and vegetables.” Anyhoo, you can imagine the sheer terror and embarrassment when I dropped a steamy, extremely foul-smelling deuce right there on the dance floor. I ran out the door crying and was banned from ever going back. I couldn’t completely get the stain out of my favorite dancing britches, and that makes me very sad."

10 / 10
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  • wia...
  • Taken for 1 to 6 months
  • September 12, 2019

"I am on 10 mg of amitriptyline for major depression severe anxiety. It has been a godsend. It saved my life."

10 / 10
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  • Dor...
  • January 29, 2011

Amitriptyline "Since going back to this med, my morning tiredness is gone, as well as weakness in general. I love it."

10 / 10
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  • Ree...
  • Taken for 1 to 2 years
  • August 11, 2024

"Last year, I was struggling with major severe depression, then my doctor put me on amitriptyline. After one month, the depression disappeared, and everything was great. It is the best."

10 / 10
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  • Anonymous
  • April 9, 2008

Amitriptyline "This medication not only helped my mood to pull me out of my depression but it also decreased my migraines which could last for several days at a time."

9 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • May 12, 2018

Amitriptyline "This helped me tremendously in a matter of a few weeks. I was so hopeless that nothing would work and that I would never be myself again. I’m so thankful for this medicine. It changed my life."

10 / 10
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  • Hea...
  • October 26, 2009

Amitriptyline "Been taking for 15 years. Started as an antidepressant but also helps back pain and sleep."

10 / 10
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  • Phi...
  • December 1, 2009

Amitriptyline "Happy thoughts once again."

8 / 10
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  • Cho...
  • August 29, 2019

"I wake up with energy, happier."

10 / 10
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  • cw2...
  • Taken for 1 to 2 years
  • June 28, 2017

"Most effective antidepressant. Works way better than SSRI and Effexor."

10 / 10
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  • Kta...
  • Taken for 1 to 2 years
  • November 13, 2020

"10-year roundabout of drug after drug for depression, hospital admissions, etc., TMS...finally put on amitriptyline, and it's been magic."

10 / 10
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  • Anonymous
  • January 19, 2011

Amitriptyline "Have tried many others: Zoloft, citalopram, nortriptyline. Other than side effects, this medicine works great. Just have to be careful with the sedative properties."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • August 8, 2012

"Felt a bit groggy at first but now I'm good! Mood swings cut way down now that I'm sleeping!"

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.