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User Reviews for Endep

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Interstitial Cystitis 1 reviews 28 medications
   
10
Fibromyalgia 6 reviews 20 medications
   
7.5
Depression 4 reviews 80 medications
   
7.3
Pain 8 reviews 1094 medications
   
7.1
Insomnia 4 reviews 109 medications
   
5.5
Anxiety and Stress 3 reviews 9 medications
   
2.7
Summary of Endep reviews 26 reviews 6.7

Reviews for Endep

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For Anxiety and Stress "Been taking it for 6 years initially for depression then anxiety and stress and it's one of the worst things to happen to me. Constant eczema where my skins gets very itchy and sore that I have scars all over, constipation is probably the worst as I've had periods of vomiting to stomach being sore and bloated, blurred vision, it's addictive contrary to what doctors say as I have been trying to get off it for 2 years slowly and been admitted to hospital twice in that time for substance abuse relating to endep. Doctors can't understand why I have been on it for so long. Take mine at night as you get drowsy of a day on higher than 50mg (most I taken was 75mg) now on 10mg and still get constipation."

   
1.0

Chriso1 October 22, 2016

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For Fibromyalgia "Wonderful for my fibromyalgia. It helps reduce pain and helps me get a solid nights sleep. I take 50mg 2 hours before bedtime. Recommend this highly."

   
10

Anonymous (taken for 1 to 2 years) October 19, 2016

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For Pain "I've been taking 10mg Endep for 2 weeks for bladder pain. I may have a mild case of interstitial cystitis but I haven't been officially diagnosed yet. I have found it has worked really well with the pain. I went from being in pain all the time to only a couple of times and it's been manageable. I have dry mouth and an increased appetite from Endep but the worst side effect is constant drowsiness and a general feeling of being drugged up."

   
8.0

Hkfygcjb August 10, 2016

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For Depression "i use endep for 14 years for my depresion it is very good for me i take 100 mg every nighte i fill verey good and sleep verey nice and good no thinking no sad just i be relax thanks my god"

   
10

Abdolkhadir.athari August 5, 2016

8 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Depression "I have only been on this drug for two weeks and as yet not noticed any difference with my depression. My anxiety levels are up, I have swooshing, buzzing noises in my ears, I even feel dizzy while seated and even just turning my head from side to side. I have noticed tingling in my fingers. My balance is affected, feeling like a drunk person. My head throbs."

poey May 23, 2016

18 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Insomnia "Been on endep 10mg for 4 weeks .for insomnia. Although it helps me sleep the longer I take it the dopier I get during day. Feel like I am permanently sedated. Like my brain is shrinking and my head is full of cotton wool all day. No motivation to do anything.."

   
1.0

Theg (taken for less than 1 month) March 31, 2016

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For Depression "I was on 75mg of Endep & noticed 2 extreme side effects which lead to me having to stop taking the medication. The first was rapid & excessive weight gain; I gained 6 kgs (13 pounds) within 8 weeks (at 160cm, this is quite a bit of weight). I had no change in my diet, my exercise stayed the same, so the Endep was the only thing that could have caused the weight gain. The second was extreme Night Terrors. These occurred every night & were extremely frightening for myself & family, as I would wake up screaming & kicking every night. This occurred almost immediately after starting the Endep. Since stopping the Endep 2 weeks ago, the Night Terrors have ceased completely, & I have lost 1kg with no change in diet."

   
4.0

affff (taken for 1 to 6 months) October 15, 2015

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For Fibromyalgia "I'm on 150 and it doesn't do anything"

   
3.0

Frannyyyyyy October 13, 2015

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For Anxiety and Stress "Dramatic weight gain, heartburn, sleeplessness"

   
1.0

Me and everyone else September 13, 2015

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For Insomnia "I take Endep for depression. If I take it in the evening or at night I cannot sleep at all; just toss and turn all night. Therefore, I only take it in the morning."

   
1.0

rlltrash (taken for less than 1 month) July 28, 2015

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For Pain "My dr prescribed this as my pain from arthritis was constantly waking me up every night from day 1 it has enabled me to get a full nights sleep I will keep taking it as nothing else has worked it does not in any way interfere with daily work, a god send"

   
9.0

Zubie (taken for less than 1 month) July 10, 2015

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For Insomnia "I have been taking Endep 10 for approx 3 weeks and have I used a variety of sleeping meds. Endep is the best by far. I take it 3 hours prior to sleep and have no problems getting to sleep and if I do wake during the night I go back to sleep straight away. It can make me a little drowsy in the morning but nothing like other meds."

   
9.0

Jandal February 2, 2015

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For Fibromyalgia "I have been on Endep for 35 years. I have fibromyalgia, chronic fatigue syndrome and plenty more. In the last six months I have been getting very odd symptoms such as the ones provided within this article!( sudden weight gain, inability to eat properly, tiredness, rounded face,weakness, sore mouth and tongue, to slight more depression, At the moment I am on a doctor treadmill ...everyone from my endocrinologist to a neurologist, GP and many more have put their hands up saying I don't know!! The medicines work really well for fibromyalgia but after some time they can work against you! Please look at the list of side effects. I have a lot of them. Good luck!"

   
6.0

Rhondiga (taken for 10 years or more) December 3, 2014

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For Insomnia "I took Endep 25 for headaches. I felt drowsy even the next day. So I went to Endep 10. I need to to take it about 2 hours before sleep. Side effect - ear noise which is going on for over 1 week now after 1 tablet. Going to stop it for a while due to side effect."

   
7.0

Mr Mal March 21, 2014

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For Anxiety and Stress "I've been taking 20mg of amitriptyline for 2 weeks and I have slept extremely well every night and I have so much more energy during the day. I sleep solid and right through the night which is unusual for me these days as my stressful job and back pain often leaves me anxious and tossing and turning every night and then I end up grumpy, run down and feeling sick as a result. So far it has not helped with my anxiety or depression but getting a good night sleep helps me cope and gives me energy to attend yoga and exercise. I believe the dose may be too small to help the depression. I'm also taking this as it is the most studied antidepressant used during pregnancy and the SSRI's give me insomnia. I have almost no side effects so far."

   
6.0

Nik85 (taken for less than 1 month) December 13, 2013

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For Fibromyalgia "I have been on Endep for Fibromyalgia for 10 years. At first the affect was awesome, for the first time in many years I slept properly and had hardly any pain. Over the years though, this has changed. I started off on 50mg per day and over the years had to have it increased to the maximum does of 150mg. Recently I have been having heart palpatations and an increased heart rate. My doctor has put it down to the extended time I have been on Endep at such a high rate. So now I am on a drug to lower my heart rate, which works well, but my doctor is getting me to try to cut down on the Endep with a view of going off it altogether and hopefully also going off the drug that I need to lower my heart rate. It's not working I'm in too much pain"

   
7.0

Lemmingham November 5, 2013

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For Pain "I have fibromyalgia and take Tramadol 150mg daily. Recently had a flare of trigeminal neuralgia and widespread neuropathic pain and Tramadol was not working for this. Doctor put me back onto Endep, which I had given up previously as the side effects were very strong. Am now on only 5mg at 7pm and find sleep and pain relief much better. Still feel hungover in the morning."

   
5.0

susieoq October 18, 2013

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For Migraine Prevention "Started getting migraines at 18. I'm now 46. Vomiting so bad I used to go to hospital 1-2x per month to go on a drip to rehydrate. Made a professional career virtually impossible. Been on Sandomigran for 25 years. Had every possible treatment. Then 5 years ago a hospital locum prescribed Endep. That was the end of my migraines. I was suicidal for 2-3 weeks but then back to normal. I now take 1 x 50mg tab every second night. Endep is brilliant!"

   
10

Gerbras September 20, 2013

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For Pain "I am taking Endep 100mgs at night for nerve pain in my lower left leg & the outer side of my right leg. The nerve pain was intolerable and I seriously was suicidal. I have been on Endep as well as Baclofen and Epilim, for 7 years & can now enjoy my life so much more. The down side is loss of libido and dry mouth, but without Endep I could not enjoy my life at all."

   
9.0

barsha55 (taken for 5 to 10 years) August 8, 2013

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For Pain "Started taking 10mg then up to 25 for severe long term migraines/ headaches. Meds work well, am considering lowering dosages and getting off medicines all together to start family now though."

   
8.0

Megatron14 July 29, 2013

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For Pain "Was prescribed Endep 10 for the pain associated with an attack of Shingles. The effect was very good as I had very little pain from the rash or the nerves affected by shingles."

   
9.0

Chewy 1 July 12, 2013

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For Pain "10mg used to provide a pain free nights sleep. I have a pinched sciatic nerve. After cortizone injection under general anesthetic I experienced cramps that disturbed my sleep. This medicine is now giving me a good nights sleep and I wake refreshed in the morning."

   
9.0

Foges (taken for less than 1 month) March 19, 2013

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For Fibromyalgia "I had unrefreshing sleep, and needed a lot of it. Endep is awesome as can now get a good night sleep, feel refreshed for a few hours after waking, and decreases my body aches. No negative side effects for me luckily."

   
9.0

Anonymous May 9, 2012

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For Fibromyalgia "Endep had a very quick effect and eliminated the muscular pain that I have suffered for more than ten years. I do feel drowsy, its seems to have a calming effect on me and I sleep amazingly well."

   
10

Anonymous December 17, 2011

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For Interstitial Cystitis "I had been tested for everything to try and find the cause of constant bladder infections, or so I thought. It wasn't till I saw a urologist that I found the answer to my problem. I never had Bladder infections, but chronic cystitis, found after some very intrusive camera shots of my bladder. She first tried stretching my bladder to see if this helped. It didn't. She then suggested Endep, not for depression but it had been used for cystitis and burning mouth, which I also suffer from. It has helped my burning bladder problem 100% as long as I don't forget to take my tablets. If I forget just one, I have the pain back for about two weeks before I get back on track. My burning mouth is also about 60% better but not gone. "Side effects weight gain"."

   
10

shell09 July 12, 2011

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