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User Reviews for Endep

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition Avg. Ratings Reviews Compare
Fibromyalgia
7.9
   
7 reviews 20 medications
Interstitial Cystitis
7.5
   
2 reviews 30 medications
Pain
6.8
   
9 reviews 1110 medications
Depression
6.6
   
6 reviews 80 medications
Insomnia
5.9
   
6 reviews 108 medications
Anxiety and Stress
2.7
   
3 reviews 9 medications
Summary of Endep reviews 6.6 33 reviews

Reviews for Endep

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For Insomnia "I started taking Endep 10 for insomnia from menopause, this was too weak and no effect so after a week my Doctor upped to Endep 25. This works really well for me and most nights I sleep far more soundly and if I wake up fall back to sleep pretty quickly. Some days I wake up a little bit lethargic and slow to get out of bed but once I'm up I am my usual motivated self. This has worked well for me and I feel heaps better than when I was taking sleeping pills."

   
9.0

Nickers (taken for 1 to 6 months) October 11, 2018

11 users found this comment helpful.
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For Fibromyalgia "Have been on this for 2 days now, first and second night, best sleep ever...wait & see !!!"

   
10

Chrissiem (taken for less than 1 month) July 31, 2018

5 users found this comment helpful.
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For Interstitial Cystitis "I have to say that Endep is simply wonderful in shutting down the symptoms of interstitial cystitis (IC) BUT the side effects are horrendous. I have tried for 5 days but every day I feel worse. So I have given up . I will go back to Ditropan and try increasing the dose. If the people who make Endep ever read this , PLEASE do something to reduce the side effects because this is such a wonderful medication for those of us who have IC, but the side effects are just to much to deal with."

   
5.0

JT (taken for less than 1 month) July 28, 2018

5 users found this comment helpful.
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For Pain "I got shingles in December 2016 and have been on and off endep since then. It helped my shingles pain but I get very little sleep. I have to make a choice of not sleeping due to pain, taking endep and have no pain and still not sleep. If there was a natural alternative I'd use that but I've been told that there isn't any. I take Axit for my PTSD and OCD, plus norflex for my grinding teeth at night. I've had insomnia since I was a kid and refuse to take sleeping pills again."

   
4.0

Raysa (taken for 1 to 2 years) April 7, 2018

2 users found this comment helpful.
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For Depression "Hello I've been on probably every SSRI except prozac which all had a short lived outcomes. Finally after 20 years I've been put on an SNRI and its working, started on 10mg endep for appetite which didn't work and given valium for the shakes and tears. Valium stopped working in less than 2 weeks, so I stopped taking it and psych increased the dosage of endep to 25mg, and I'm actually feeling good, after 6 months of awfulness, this might be my answer. Sleeping well, lots of energy, memory and concentration is better and no more teeth grinding. No real side effects except for the first day I started on the 10mg I copped a bad headache but that was it."

   
10

Seehowthisgoes (taken for less than 1 month) April 7, 2018

9 users found this comment helpful.
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For Depression "I dropped 50mg of Endep cold turkey over 3 years ago. I ended up with 24/7 migraines for a month, collapsed and was taken to Hospital and unfortunately the Doctor started me back on Endep He said they were good for Headaches. Left Hospital on a small dose and started having Panic Attacks all day every day, collapsed and was put back in Hospital. They increased my Dose of Endep. I am now trying to get off it again as it is not working, I am decreasing the Endep by 5mg a week."

   
1.0

Pattie March 15, 2018

2 users found this comment helpful.
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For Insomnia "Works ok. I have Bulge discs, tear, depression & anxiety . On this I sleep well. Loss of sex drive, anxiety and stress still high. Doesn't help the pain so much in my back. I sleep really well at night after 100mg, but I wake up tired and need to nap for 2-3 hours and in bed by 9:30pm. Just always wanting to sleep and lazy."

   
5.0

aaaaaaaallllllll January 6, 2017

29 users found this comment helpful.
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For Anxiety and Stress "Been taking it for 6 years initially for depression then anxiety and stress and it's one of the worst things to happen to me. Constant eczema where my skins gets very itchy and sore that I have scars all over, constipation is probably the worst as I've had periods of vomiting to stomach being sore and bloated, blurred vision, it's addictive contrary to what doctors say as I have been trying to get off it for 2 years slowly and been admitted to hospital twice in that time for substance abuse relating to endep. Doctors can't understand why I have been on it for so long. Take mine at night as you get drowsy of a day on higher than 50mg (most I taken was 75mg) now on 10mg and still get constipation."

   
1.0

Chriso1 October 22, 2016

16 users found this comment helpful.
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For Fibromyalgia "Wonderful for my fibromyalgia. It helps reduce pain and helps me get a solid nights sleep. I take 50mg 2 hours before bedtime. Recommend this highly."

   
10

Anonymous (taken for 1 to 2 years) October 19, 2016

48 users found this comment helpful.
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For Pain "I've been taking 10mg Endep for 2 weeks for bladder pain. I may have a mild case of interstitial cystitis but I haven't been officially diagnosed yet. I have found it has worked really well with the pain. I went from being in pain all the time to only a couple of times and it's been manageable. I have dry mouth and an increased appetite from Endep but the worst side effect is constant drowsiness and a general feeling of being drugged up."

   
8.0

Hkfygcjb August 10, 2016

76 users found this comment helpful.
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For Depression "i use endep for 14 years for my depresion it is very good for me i take 100 mg every nighte i fill verey good and sleep verey nice and good no thinking no sad just i be relax thanks my god"

   
10

Abdolkhadir.athari August 5, 2016

47 users found this comment helpful.
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For Depression "I have only been on this drug for two weeks and as yet not noticed any difference with my depression. My anxiety levels are up, I have swooshing, buzzing noises in my ears, I even feel dizzy while seated and even just turning my head from side to side. I have noticed tingling in my fingers. My balance is affected, feeling like a drunk person. My head throbs."

poey May 23, 2016

39 users found this comment helpful.
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For Insomnia "Been on endep 10mg for 4 weeks .for insomnia. Although it helps me sleep the longer I take it the dopier I get during day. Feel like I am permanently sedated. Like my brain is shrinking and my head is full of cotton wool all day. No motivation to do anything.."

   
1.0

Theg (taken for less than 1 month) March 31, 2016

52 users found this comment helpful.
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For Depression "I was on 75mg of Endep & noticed 2 extreme side effects which lead to me having to stop taking the medication. The first was rapid & excessive weight gain; I gained 6 kgs (13 pounds) within 8 weeks (at 160cm, this is quite a bit of weight). I had no change in my diet, my exercise stayed the same, so the Endep was the only thing that could have caused the weight gain. The second was extreme Night Terrors. These occurred every night & were extremely frightening for myself & family, as I would wake up screaming & kicking every night. This occurred almost immediately after starting the Endep. Since stopping the Endep 2 weeks ago, the Night Terrors have ceased completely, & I have lost 1kg with no change in diet."

   
4.0

affff (taken for 1 to 6 months) October 15, 2015

37 users found this comment helpful.
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For Fibromyalgia "I'm on 150 and it doesn't do anything"

   
3.0

Frannyyyyyy October 13, 2015

11 users found this comment helpful.
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For Anxiety and Stress "Dramatic weight gain, heartburn, sleeplessness"

   
1.0

Me and everyone else September 13, 2015

56 users found this comment helpful.
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For Insomnia "I take Endep for depression. If I take it in the evening or at night I cannot sleep at all; just toss and turn all night. Therefore, I only take it in the morning."

   
1.0

rlltrash (taken for less than 1 month) July 28, 2015

29 users found this comment helpful.
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For Pain "My dr prescribed this as my pain from arthritis was constantly waking me up every night from day 1 it has enabled me to get a full nights sleep I will keep taking it as nothing else has worked it does not in any way interfere with daily work, a god send"

   
9.0

Zubie (taken for less than 1 month) July 10, 2015

136 users found this comment helpful.
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For Insomnia "I have been taking Endep 10 for approx 3 weeks and have I used a variety of sleeping meds. Endep is the best by far. I take it 3 hours prior to sleep and have no problems getting to sleep and if I do wake during the night I go back to sleep straight away. It can make me a little drowsy in the morning but nothing like other meds."

   
9.0

Jandal February 2, 2015

110 users found this comment helpful.
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For Fibromyalgia "I have been on Endep for 35 years. I have fibromyalgia, chronic fatigue syndrome and plenty more. In the last six months I have been getting very odd symptoms such as the ones provided within this article!( sudden weight gain, inability to eat properly, tiredness, rounded face,weakness, sore mouth and tongue, to slight more depression, At the moment I am on a doctor treadmill ...everyone from my endocrinologist to a neurologist, GP and many more have put their hands up saying I don't know!! The medicines work really well for fibromyalgia but after some time they can work against you! Please look at the list of side effects. I have a lot of them. Good luck!"

   
6.0

Rhondiga (taken for 10 years or more) December 3, 2014

72 users found this comment helpful.
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For Insomnia "I took Endep 25 for headaches. I felt drowsy even the next day. So I went to Endep 10. I need to to take it about 2 hours before sleep. Side effect - ear noise which is going on for over 1 week now after 1 tablet. Going to stop it for a while due to side effect."

   
7.0

Mr Mal March 21, 2014

68 users found this comment helpful.
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For Anxiety and Stress "I've been taking 20mg of amitriptyline for 2 weeks and I have slept extremely well every night and I have so much more energy during the day. I sleep solid and right through the night which is unusual for me these days as my stressful job and back pain often leaves me anxious and tossing and turning every night and then I end up grumpy, run down and feeling sick as a result. So far it has not helped with my anxiety or depression but getting a good night sleep helps me cope and gives me energy to attend yoga and exercise. I believe the dose may be too small to help the depression. I'm also taking this as it is the most studied antidepressant used during pregnancy and the SSRI's give me insomnia. I have almost no side effects so far."

   
6.0

Nik85 (taken for less than 1 month) December 13, 2013

138 users found this comment helpful.
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For Fibromyalgia "I have been on Endep for Fibromyalgia for 10 years. At first the affect was awesome, for the first time in many years I slept properly and had hardly any pain. Over the years though, this has changed. I started off on 50mg per day and over the years had to have it increased to the maximum does of 150mg. Recently I have been having heart palpatations and an increased heart rate. My doctor has put it down to the extended time I have been on Endep at such a high rate. So now I am on a drug to lower my heart rate, which works well, but my doctor is getting me to try to cut down on the Endep with a view of going off it altogether and hopefully also going off the drug that I need to lower my heart rate. It's not working I'm in too much pain"

   
7.0

Lemmingham November 5, 2013

56 users found this comment helpful.
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For Pain "I have fibromyalgia and take Tramadol 150mg daily. Recently had a flare of trigeminal neuralgia and widespread neuropathic pain and Tramadol was not working for this. Doctor put me back onto Endep, which I had given up previously as the side effects were very strong. Am now on only 5mg at 7pm and find sleep and pain relief much better. Still feel hungover in the morning."

   
5.0

susieoq October 18, 2013

119 users found this comment helpful.
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For Migraine Prevention "Started getting migraines at 18. I'm now 46. Vomiting so bad I used to go to hospital 1-2x per month to go on a drip to rehydrate. Made a professional career virtually impossible. Been on Sandomigran for 25 years. Had every possible treatment. Then 5 years ago a hospital locum prescribed Endep. That was the end of my migraines. I was suicidal for 2-3 weeks but then back to normal. I now take 1 x 50mg tab every second night. Endep is brilliant!"

   
10

Gerbras September 20, 2013

61 users found this comment helpful.
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