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Endep and Headaches: What Users Say

Headaches: mentioned by 4 users (8.3%)

Based on user experiences from 48 Endep reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 12.5%
weight gain 12.5%
dizziness 8.3%
headaches 8.3%
tiredness 8.3%
anxiety 6.3%
dry mouth 6.3%
insomnia 6.3%

Reviews for Endep

Commonly mentioned side effects
  • Hay...
  • October 5, 2019

For Pain "I am 37 years old. I started getting headaches at 13, from what I can remember. I went on day to day, year after year. When I was 26, I was put in hospital with all the drugs. Well, I was getting headaches monthly, bad ones. I couldn’t even handle light. As the years went on, I got them once every 6 months, putting me in the hospital. Then they started coming on every couple of months, then once a month, all the way down to 3 a week. By this stage, my face was numb. I couldn’t talk or walk. I could not have any light, losing memory. About 3 months ago, I went to a brilliant doctor and I couldn’t see, so I needed help going there and walking to him. He said to me, 'have you heard of ENDEP?' I have taken my Endep every night since for over 3 months now. And only had two very, very small headaches. I’ve been given a second chance at life. I’m very grateful. I thank my doctor so very much."

10 / 10
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  • tri...
  • August 30, 2007

For Pain "I have been taking Endep for about 20 years for pain and to help me sleep. I have seen many specialists and GPs over the years, and none of them warned me about chronic periodontal disease because of dry mouth. I was on 50mg per day. I had to have three teeth removed. I am now on 25mg. I have many health problems, apparently due to a seronegative autoimmune disease. I am also experiencing symptoms of headaches, vertigo, dizziness, balance problems, etc."

4 / 10
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172 Report
  • See...
  • Taken for less than 1 month
  • April 7, 2018

For Depression "I've been on probably every SSRI except Prozac, which all had short-lived outcomes. Finally, after 20 years, I've been put on an SNRI, and it's working. Started on 10 mg Endep for appetite, which didn't work, and given Valium for the shakes and tears. Valium stopped working in less than 2 weeks, so I stopped taking it, and the psych increased the dosage of Endep to 25 mg, and I'm actually feeling good. After 6 months of awfulness, this might be my answer. Sleeping well, lots of energy, memory and concentration are better, and no more teeth grinding. No real side effects except for the first day I started on the 10 mg, I copped a bad headache, but that was it."

10 / 10
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55 Report

Frequently asked questions

  • poe...
  • May 23, 2016

For Depression "I have only been on this drug for two weeks, and as yet, I have not noticed any difference with my depression. My anxiety levels are up, I have swooshing, buzzing noises in my ears. I even feel dizzy while seated and even just turning my head from side to side. I have noticed tingling in my fingers. My balance is affected, feeling like a drunk person. My head throbs."

2 / 10
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71 Report

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