Fosamax and Fatigue: What Users Say

• Nat...
• Taken for less than 1 month
• March 22, 2020

For Osteoporosis "I took two weekly doses of Fosamax then stopped because of side effects. Rapid weight gain, acute abdominal distension (like I’m 7 months pregnant), aching back, aching hips, fatigue, and random itching. Been off it for a month and side effects have not abated at all. It’s like I woke up and suddenly aged an extra 30 years overnight. Hope the side effects go away soon."

• Pat...
• February 21, 2023

For Osteoporosis "I started taking Fosamax once a week a month ago and took three doses. I have had horrible depression, fatigue, and body aches. I talked to my doctor and was told that the depression was not a side effect. I have never felt this bad before and refuse to take it ever again. It is a horrible drug."

• Tis...
• Taken for 1 to 6 months
• November 16, 2019

For Prevention of Osteoporosis "I was prescribed Fosamax for osteopenia. I have taken a total of 6 doses. I had no side effects for the first 2 weeks. By the 3rd week, extreme fatigue and headaches. I continued for another 3 weeks hoping symptoms would go away. When they didn't, I discontinued taking it. But a week AFTER I quit, I developed severe bone pain, unbearable pain which is worse at night. I am taking arthritis drug to make the days bearable. SOMEONE PLEASE TELL ME THIS PAIN EVENTUALLY GOES AWAY!! I will be calling my Dr. on Monday."

• Anonymous
• Taken for less than 1 month
• March 19, 2025

For Osteoporosis "After just one dose, seven hours later, I had a fever, chills, nausea, fatigue, and stomach issues. The second day, I was tired and chilled in the evening with bone pain in my back and also the third morning. Very achy. I am considering not taking any more doses."

• Boo...
• Taken for less than 1 month
• March 15, 2022

For Osteoporosis "I was asymptomatic but deemed high risk for fracture since diagnosed with osteoporosis. I respect some who’ve actually benefited from Fosamax. However, this has been a drug nightmare with symptoms similar to others here on this site. First week taking weekly Fosamax 70 followed next day by nonstop diarrhea for remainder of the week. Second week dose 2 had ongoing diarrhea, chills, nausea, fatigue, and debilitating cramps as if punched repeatedly in the stomach. To my FP’s irritation, I strongly refused further treatment after 2 weeks, stopping prior to the 3rd dose. Also declined Prolia injectable as an alternative as it must be followed by oral biophosphonates after injections are discontinued. I’m still dealing with diarrhea and fatigue impacting the quality of life. Please do extensive reading on side effects before pursuing Fosamax or other bone health drugs. I’m now pursuing a more natural option through exercise, nutrition, vitamins D3, calcium, K2, and fish oil."