Skip to main content

Humira for Rheumatoid Arthritis User Reviews (Page 3)

Reviews for Humira

Commonly mentioned side effects
  • jay...
  • Taken for 1 to 6 months
  • April 8, 2015

"Humira lowered my immunity to where I suddenly got severe pneumonia that spread very fast. I had never had lung problems before this happened. After 2 weeks in the hospital with all different kinds of antibiotics and antifungal and drained fluid from the lung, I started to get better. This was after stopping the Humira the first day in the hospital. Now I have a scarred lung and cold to show for it. I will not be going back on it!"

1 / 10
Was this helpful?YesNo
53 Report
  • In...
  • November 30, 2015

"Began experiencing rheumatoid arthritis in spring of 2014. Was put on methotrexate and Humira. The arthritis was affecting my wrists, hands, and fingers with severe pain, with some additional pain to both knees, ankles, feet, and toes. At 52 years of age, the debilitating pain was not acceptable. Almost immediate relief from pain was achieved with these medications, but the side effects began. Yeast infections, skin rashes, etc. Quit both meds in December 2014. The severe pain in both hands has returned. Have an appointment in January 2016 with a new rheumatologist for a second opinion for treatment. For those with allergies and sinus infections, try eating some raw local honey each day. Eating honey has taken headaches away for me."

5 / 10
Was this helpful?YesNo
48 Report
  • Anonymous
  • November 8, 2011

"I have moderate to severe rheumatoid arthritis, and until I got on Humira, I was unable to do much of anything. I was misdiagnosed for almost 2 years, and since the first injection, I've had great success."

9 / 10
Was this helpful?YesNo
65 Report

Frequently asked questions

  • Hum...
  • May 6, 2016

"I was put on Humira after trying DMARDs that just wouldn't control my RA, which went to being severe in a very short space of time from first diagnosis. I have now been on the drug together with 10 mg methotrexate for 2 years and haven't looked back. When I think back to being in so much pain that I couldn't get out of bed and had to have my husband help me climb the stairs, there is no comparison. Now I exercise 3 times a week and am able to work without being constantly off ill. I did take shingles last year, which wasn't very pleasant, but other than that, I haven't had any other side effects, thankfully. I feel like I've been given my life back."

10 / 10
Was this helpful?YesNo
45 Report
  • Ric...
  • Taken for 2 to 5 years
  • March 31, 2015

"On Humira for about 4-5 years now. I understand the risk of your immune system being compromised, however, the relief I receive outweighs in my mind that risk. I am overall a healthy and active individual. I'm 56. I take Methotrexate in combination with the Humira. Early January 2015, I had a knee replacement. Successful surgery. I needed to be off the Humira for more than 2 months due to that. During that time, I had major flare-ups. I've been injecting again with the Humira pen, 3 times in 3 weeks...it's not yet working again. Has anyone experienced this, being off of it for a few months and then starting up and the Humira being non-effective? I'd be interested to know. I'm at the point to ask my rheumatologist what gives? Different treatment options?"

8 / 10
Was this helpful?YesNo
46 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Anonymous
  • July 24, 2008

"The medicine has given my mother a new lease on life. After trying many medicines, Humira has given her better mobility and a lot less pain (she refers to it as discomfort or stiffness). Also, kudos to the company for recently, my mother had trouble with the pharmacy, and when she contacted the company, they arranged for her to receive it through a pharmacy in another town and delivered to her by UPS. They took care of everything for her. Thanks on her behalf."

9 / 10
Was this helpful?YesNo
67 Report
  • lan...
  • February 28, 2008

"Excellent drug for me. My illness was misdiagnosed, thus when it came to using the meds for controlling the disease, I either had mild to severe allergic reactions or broke through the meds within a year and a half. I am in the 3rd stage of RA. Drugs like Humira were out of reach for those of us in the moderate to severe stage due to cost. Humira is my last resort. It helps me tremendously."

10 / 10
Was this helpful?YesNo
72 Report

More FAQ

  • Pin...
  • Taken for 1 to 6 months
  • June 11, 2017

"Diagnosed with RA in 2014, started with methotrexate and low-dose prednisone. 46 yrs. Had other medical conditions and taken off meds for approximately 1 1/2 years. Placed back on meth/pred in 2016. Started Humira in Feb 2017, weekly shots, and taken off meth/pred. Then went to Humira every other week and placed back on meth/pred. Now Humira every other week only. Then informed my RA was being managed and taken off meth/pred once again. It is now June, and I feel terrible. My hands are killing me. They feel like they are on fire/placed in a press/hot/cold/asleep/etc. My feet are starting to hurt a lot, and my knees too. I am so, so tired. I can sleep constantly. I feel like I have the flu daily, with a cough and congestion. Making another doctor's appointment."

1 / 10
Was this helpful?YesNo
40 Report
  • ckn...
  • May 27, 2011

"This is the second time I have started Humira (three weeks ago). It gave me great relief the first time around, but I was forced to quit due to a change in insurance. In the four months I was off Humira, my inflammation and pain accelerated. I worked with my doctor, COBRA provider, and Humira customer service to be reinstated. I have been on it now for a month, with one injection every two weeks. I find the auto injector easy to use and safer than a syringe. I have found that sinus infections can be reduced by the use of mupirocin ointment in my nostril once a day and by using the NeilMed sinus rinse every night."

9 / 10
Was this helpful?YesNo
57 Report
  • sAV...
  • Taken for 10 years or more
  • December 3, 2022

"I have been on Humira ever since it was available in the US. I am also taking methotrexate. I have rheumatoid arthritis and psoriatic arthritis and uveitis, but ever since I have been on this combination, I have been problem-free! I have pictures to prove how much I suffered before: huge inflamed knees, itching rash on half the body."

10 / 10
Was this helpful?YesNo
15 Report
  • Dai...
  • Taken for 2 to 5 years
  • May 9, 2015

"I have been taking Humira for 2 years now. I have had RA since 2008. No one in my family has had RA. I noticed the first week of taking Humira that my pain and swelling was gone. I do get sinus infections and dry skin on my feet. I am SO happy not having as much pain. I can live with the infections or dry feet."

10 / 10
Was this helpful?YesNo
45 Report
  • Anonymous
  • March 14, 2012

"After many years on Imuran, my rheumatoid arthritis was no longer controlled. I was in terrible pain for months. About three days after my first Humira injection, I felt amazing. Didn't realize how bad the pain had been for so long. Then I had a setback. I was taking Imuran with the Humira and ran out of Imuran for three days. All the pain returned. I didn't go back to being pain-free after that, and some symptoms returned. My doctor switched me to Humira biweekly and injections of methotrexate weekly. Pain again subsided. I have had an itchy, puffy reaction at the site of Humira injections. Now, after 3 or 4 shots, I have horribly itchy, watery, burning eyes. Not sure if this is some kind of allergic indication."

8 / 10
Was this helpful?YesNo
55 Report
  • Anonymous
  • January 16, 2009

"I have juvenile rheumatoid arthritis as well as uveitis as a result of the arthritis. I'm 13 years old, and I've been using Humira for the past six months. I'm using Humira to try to control both the pain and the eye disease. This drug is pretty much the last option for me, and it is thankfully working. I hope that Humira will continue to work and that I won't have side effects like I did with just about everything else. I'm glad that something is finally working."

8 / 10
Was this helpful?YesNo
62 Report
  • Bos...
  • Taken for less than 1 month
  • April 6, 2019

"Diagnosed with RA at 22 years. Started with Plaquenil, it helped for a year, then we added methotrexate. Took some time to get the dose right due to nausea. That combo helped for about 2 years. Then added Enbrel. Added Meloxicam. Prednisone as needed for the worst flare-ups. After serious ulcers, I stopped the meloxicam and prednisone as they both increase the chances of getting ulcers. Enbrel only worked for 1.5 years. Just switched to Humira, still taking Plaquenil and methotrexate. I prefer the syringes to the pens. Some relief in the first week, hoping it works for more than a year or two. Many illnesses due to the compromised immune system, and extreme fatigue, but my RA is so severe I am fully disabled without these meds. I hope I can find one that will last a little longer. With the Humira support card, I have not had to pay for this drug."

5 / 10
Was this helpful?YesNo
31 Report
  • imj...
  • June 10, 2016

"For rheumatoid arthritis. I was diagnosed in 2011; nothing works well. Until I was allowed Humira 40 mg pen plus 20 mg of methotrexate every 2 weeks. Humira works overnight, none of the side effects. I am back to my perfect self again. Now I am waiting for another shoe to drop: medications stop working, insurance stops covering, liver funk out, etc."

10 / 10
Was this helpful?YesNo
41 Report
  • Anonymous
  • August 29, 2011

"I tried many drug combinations prior to using Humira, and nothing worked. After my second dose of Humira, I noticed the inflammation subside and was virtually pain-free for the first time in years. Very little side effect most of the time, but did have much more occurrence of pharyngitis on this medicine."

10 / 10
Was this helpful?YesNo
51 Report
  • Di ...
  • January 17, 2014

"Been on this for almost 10 years. I now have frequent sinus headaches that are difficult to clear. Am fatigued but able to function well on this medicine, but now have stomach pain and also use methyprednisolone. Also, vasculitis has appeared in my ankle, and it's here to stay. I plan to stop and start Sulfasalazine EC to take its place as a DMARD, at least. An old case of psoriasis appeared after my 4th year but left entirely after 3 years. On my feet, and utterly painful."

8 / 10
Was this helpful?YesNo
46 Report
  • CBa...
  • January 28, 2019

"18 years old; diagnosed with JRA in Jan. 2018. Take 6 pills of Methotrexate every week, one Humira shot every 2 weeks. Not the healthiest eater, notice when I do eat healthy major differences in effects. Take medications every Saturday night to sleep off pain. When I didn't care about diet, I felt extreme effects of a headache and pain in the stomach. Noticed that if I eat a lot of food that day, my effects aren't bad. Watch your diet!! With Humira, the first few months I noticed pain went away. Was so happy; now I think that it isn't helping anymore. Feet still ache because of cold weather, but the first few months I had no pain. I read reviews and the mention of tinnitus comes a lot. I thought ears may ring/hum because of wearing earbuds, but starting to believe that it may be caused by Humira. My doc told me I may need to take another med or Humira every week. After one year, I shouldn't be given more medication but instead see improvements."

3 / 10
Was this helpful?YesNo
30 Report
  • Azi...
  • March 31, 2017

"I'm a 69-year-old woman with seronegative RA - hence it took a long time for a diagnosis. Many rheumatologists do not understand that you can be seronegative & have RA. Sad. After several years of anti-inflammatory drugs & cortisone, I was prescribed Humira. Took about 2 months & wow! Not so much pain relief, but having so much less fatigue. As I live in Australia, my experience with obtaining the drug is different from the US. My rheumatologist makes application through the federal government after other drugs have failed & they heavily subsidize. Thus far, no obvious side effects. However, reading others' comments, I wonder about the flushes at night - never had them as a menopausal symptom...... Wish you all the best in managing RA."

6 / 10
Was this helpful?YesNo
36 Report
  • Kel...
  • September 9, 2015

"I've had RA for 16 years (I'm 49 years).... I'm currently on Methotrexate (5 pills weekly) and Humira. In the past 10 months, I've had shingles twice, so I had to go off of it so that I could get the shingles vaccine. I definitely missed taking it and have suffered a bit. I just started back up and am looking forward to it kicking in! It works wonders for me.... although I will say that whenever I travel south (TN), I forget I even have arthritis.... climate matters..."

9 / 10
Was this helpful?YesNo
39 Report
  • Chu...
  • February 12, 2017

"I'm 47 years old, and I was recently diagnosed with RA. I was very reluctant about taking this medicine after reading all the possible side effects. But I have to say that this medication changed my life. The day after the first shot, I felt a little worse. But after that, I felt great-no pain, no side effects. I guess everybody is different. Good luck."

10 / 10
Was this helpful?YesNo
40 Report
  • RA...
  • Taken for 6 months to 1 year
  • December 12, 2017

"Thought this was my miracle cure for extreme RA. Nothing else seemed to work and was having trouble walking and functioning. One shot and things started returning to normal, it was wonderful to have no pain. Until the first round of A-FIB. Hospitalized, then atrial flutter. Hospitalized. Then the fainting and rapid heartbeat...220! Hospitalized. Woke up one night and could not breathe...diagnosed with pneumonia. Hospitalized. The pulmonologist revised diagnosis to pulmonary fibrosis with scarring on the lungs. Five months later, still coughing and using a nebulizer. Stopped this medicine and can breathe again. RA returned, but I'm alive. Stay away from Humira."

4 / 10
Was this helpful?YesNo
35 Report
  • MAR...
  • February 28, 2011

"I have to take the injection once a week. This medication drastically changed my condition from bad to great in March 2004. I am stable most of the time, and I consider what my life would be like. The progress of the damage is very slow, and I appreciate that fact."

10 / 10
Was this helpful?YesNo
49 Report
  • Min...
  • Taken for 1 to 6 months
  • June 16, 2018

"Absolutely terrible drug! Felt worse than ever, so many side effects, but the rheumatologist kept adding anti-inflammatories. Then prednisone, then Targin plus tablets to protect my stomach. Back pains put me in the hospital, and she still wouldn't do anything. Kept telling me I have to wait three months. Injections stung badly and bruised badly. Not even worth one star, don’t bother with this toxic drug."

1 / 10
Was this helpful?YesNo
32 Report
  • Hum...
  • Taken for 6 months to 1 year
  • July 21, 2016

"I had exactly the same thing happen to me as Jayall and Jall did. No breathing problems or skin problems prior, but on my seventh injection, I got deathly ill with pneumonia, 2 weeks in the hospital with different antibiotics and antifungal. Had lung fluid drained, now have scar tissue and COPD and psoriasis. Was and still on methotrexate and plaquenil and Orencia IV now. Joint pain not better after six months IV, just upped IV dosage, hoping for some relief. Humira made things extremely worse for me but may work for others."

1 / 10
Was this helpful?YesNo
33 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Rheumatoid Arthritis

Care guides

Symptoms and treatments

Medicine.com guides (external)