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Acyclovir and Fatigue: What Users Say

Brand names: Zovirax, Sitavig

Fatigue: mentioned by 4 users (2.1%)

Based on user experiences from 188 Acyclovir reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

itching 8.0%
burning 6.4%
headaches 4.8%
nausea 4.3%
tiredness 4.3%
depression 2.7%
pain 2.7%
dizziness 2.1%
fatigue 2.1%
blisters 1.6%

Reviews for Acyclovir

Commonly mentioned side effects
  • Dol...
  • Taken for 6 months to 1 year
  • November 14, 2013

For Herpes Simplex, Suppression "My face has developed more cystic adult acne that takes longer to heal. My eye whites have a yellowish tint. I notice I bruise easily and minor injuries take a long time to heal. I have lost weight (the good part). I feel fatigued frequently and lack energy."

3 / 10
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31 Report
  • Dol...
  • Taken for 6 months to 1 year
  • November 14, 2013

For Herpes Simplex, Suppression "My face has developed more cystic adult acne that takes longer to heal. My eye whites have a yellowish tint. I notice I bruise easily and minor injuries take a long time to heal. I have lost weight (the good part). I feel fatigued frequently and lack energy."

3 / 10
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31 Report
  • pop...
  • Taken for less than 1 month
  • August 20, 2022

For Herpes Zoster "I have been taking acyclovir 800 mg 5 times per day for 8 days for shingles (2 days more to go). I had a headache and nausea for the first couple of days taking this. The headache went away, but I still feel nauseated most of the time. I am also lightheaded, and the dizziness increases when I walk around at all. I feel very fatigued. Sometimes I have felt really agitated, like I wanted to crawl out of my skin. It has caused frequent bowel movements and some diarrhea. Between the shingles pain and the side effects, I am nearly housebound. I've been sick for a month (the rash didn't appear for 3 weeks). I'm at the end of my rope and cannot wait to get off this drug. I had shingles 8 months ago and couldn't tolerate the valacyclovir then - now that it's returned, my doctor insists I must take this to get the virus out of my system. I pray that it works. I am 64 and small build (110 pounds). I do tend to be sensitive to drug side effects."

5 / 10
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5 Report

See also:

Frequently asked questions

  • Anonymous
  • October 19, 2011

For Herpes Simplex (HSV) "I'm 25, and I've always had cold sores in my mouth since I was 4, and it can happen with sun or eating citrus. It's only getting worse now that I have braces, so my orthodontist told me about this pill and my doctor gave it to me, and I love it, EXCEPT I get a headache, fatigue, dizziness, and joint pain... but it's totally worth it!"

8 / 10
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13 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.