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5-hydroxytryptophan User Reviews & Ratings (Page 3)

Brand names: 5-HTP

5-hydroxytryptophan has an average rating of 6.5 out of 10 from a total of 186 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for 5-hydroxytryptophan

  • 5htp
  • Taken for 1 to 2 years
  • April 27, 2017

5-HTP (5-hydroxytryptophan) for Anxiety "It has been the only thing that has relieved my symptoms of depression and anxiety and possibly my pain. The only downside is that it makes me vomit, make sure you eat BEFORE taking it. Also can make stomach hurt and nauseous. That's the only reason I didn't give it a 10."

9 / 10
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67 Report
  • Bug
  • Taken for 10 years or more
  • February 3, 2013

5-HTP (5-hydroxytryptophan) for Fibromyalgia "I took 5HTP for about 10 years and it kept my Fibromyalgia pain in control enough that I could work 40 to 60 hours a week again without discomfort. Unfortunately, my family doctor had me stop taking it when my blood pressure became dangerously high. I would recommend you try it, but keep a close watch on your blood pressure."

8 / 10
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95 Report
  • anony...
  • May 14, 2015

5-HTP (5-hydroxytryptophan) for Anxiety "This supplement has really worked for me! The only problem is after about a month of taking it I have started experiencing ringing in my ears and pressure headaches. But, it does boost my mood and I haven't mood swings or anxiety like before I started taking this. Also, I find I haven't been as hungry and eating as much. This supplement would be perfect if I hadn't started having the problems with my ears and the headaches."

8 / 10
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80 Report
  • Anonymous
  • Taken for 2 to 5 years
  • April 9, 2017

5-HTP (5-hydroxytryptophan) for Anxiety "So far so good as only on it for about 5 days at 300mg per day. I have combined it with multi vitamin, vitamin b complex, niacin plus vitamin c. I am reducing big pharma medication to almost nil and feel better with 5-htp. Better sleeps, better days as I divide the dosages at breakfast, dinner and before bed. Big pharma medications only mask up the problem whilst this feels so normal."

9 / 10
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65 Report
  • Gezab...
  • Taken for 1 to 2 years
  • October 18, 2015

5-HTP (5-hydroxytryptophan) for Anxiety "Don't start off with to high dosage , it affected my sleep . Went from 150mg back to 20mg and slowly increased . Two weeks of stomach upset but it went away . I have noticed I am calmer however my body seems to get use to the dosage quickly and I need to increase it . I am up to 180 mg now and again need to up the dosage . It's really worth giving this product a try before you turn to pharmaceutical medication ."

4 / 10
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74 Report

Are you taking this medicine?

  • Mak
  • Taken for 10 years or more
  • February 7, 2020

For Depression "After being on Prozac for years, it lost it's efficacy and then tried almost all SSRI's in the market. Nothing worked. I was paralyzed with major depression, anxiety and subsequent severe insomnia. I researched 5HTP as a last resort. Followed recommendations of starting at 50 mg and every 3-4 days went up another 50mg till effective. I found absolute effectiveness at 400mg- Extended Release, taken every night. It has been a miracle in my life with no insomnia, depression or anxiety for the past 16 years! There are no side effects & or numbness. I can cry & feel emotions appropriately. Life has been Great!"

10 / 10
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42 Report
  • Monal...
  • May 12, 2015

For Depression "Was on Wellbutrin for 10 - TEN - years. As my life had only gone downhill since taking that I make the decision that prescription antidepressants are not for me and I want to feel again...and have the energy I need to function versus being in bed all day. Two days of 5 HTP and I feel like a new person. I am remembering things so clearly when it was all fuzzy before. I am starting and finishing projects that have sat for an eternity. I hope it lasts..."

8 / 10
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73 Report
  • BigTrev
  • Taken for less than 1 month
  • February 28, 2020

5-HTP (5-hydroxytryptophan) for Anxiety "I been suffering from PTSD and severe anxiety issues. The doctor put me on mirztapine at 15mg to help which it did. Saying that I was so determined to get off this nasty antidepressant because of weight gain even tho I run 30 miles a week. So silly me started taking 200mg of 5htp for 2 days. I have ended up with really bad palpitations and anxiety because of the two 200mg of 5htp and antidepressants giving me serotonin syndrome. Can someone tell me when is it safe for me to go back on my mirztapine again and how long will it take for 5htp to leave my system. Day 2 after taking 5htp and very anxious still shallow breathing etc. My doctors are useless and don't even know about 5htp. Maybe friends from across the pond can guide me better."

4 / 10
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41 Report
  • sirius
  • Taken for less than 1 month
  • May 26, 2016

5-HTP (5-hydroxytryptophan) for Insomnia "I take 5-htp for both insomnia and anxiety .The benzos and other meds didn't work anymore . So I've started to take 100 mg of 5-htp at night with a bit (7.5 mg) of mirtazipine and bang , gone for the WHOLE night. Incredible. I was so happy after searching for a remedy for years. I've started to take some small doses of 5 htp during day time ( 50mg at noon) and my anxiety is down. Now I have to let go the ATIVAN slowly but surely for my daily anxiety because it is now useless so I just have to figure out the right dosage and hope to use only this and nothing else for my sleeping problem and anxiety. ( don't forget the vitamin B6 to make it work better) So I went from a bunch of pills at night to almost nothing :-)"

9 / 10
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64 Report
  • Robb
  • Taken for 1 to 6 months
  • July 3, 2021

5-HTP (5-hydroxytryptophan) for Insomnia "Solgar 5-htp 100mg. 1xdaily. First three days it helps with my insomnia, nice 7-8h sleep, but no change with anxiety or mood, then I started waking up at 3am sweaty with elevated heart rate and having very vivid bad dreams and it continued during the day with tension headache and severe anxiety and depression, didn't know 5-htp causing it so I continued taking it. Things get worst to the level that I was stuck in dark mood and suicide feelings. I stopped taking them. 3 days later my system cleared and was back to normal. Some of us are sensitive to these " brain chemical adjusters"."

1 / 10
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29 Report
  • dolly
  • Taken for less than 1 month
  • May 18, 2020

5-HTP (5-hydroxytryptophan) for Anxiety "I'm suffering PTSD after car accident. Started on 5-HTP and after 1st week taken at night --minimum dosage had terrifying anxiety attacks magnified way beyond the level I began with, also felt aggressive, have used St Johns Wort for depression in the past with no issues."

1 / 10
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36 Report
  • Milie
  • Taken for 5 to 10 years
  • January 24, 2021

5-HTP (5-hydroxytryptophan) for Anxiety "I take 150 mg of 5HTP twice a day for many years. It has helped me with depression, anxiety and insomnia. Great product. It can be used as an antidepressant without giving me a foggy brain. I take Serotone by Apex Energetics which includes 5htp and other good ingredients for depression, anxiety and insomnia."

9 / 10
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31 Report
  • Sad
  • April 12, 2019

5-HTP (5-hydroxytryptophan) for Anxiety "Took 5 HTP 100 mg at night with magnesium, to calm my mild anxiety and sadness, help with sleep. I was post concussion and being treated for autoimmune disease. At around 6 months I increasingly noticed I was waking at night, I started getting more anxious, suicidal thoughts . During this time I also did a small intestinal bacterial overgrowth (SIBO) treatment of antibiotics which probably helped my gut work better and then started low dose naltrexone for my autoimmune disease. I started to have heart palpitations, sweating at night, depressed thoughts, panic attacks which I never had before, where you get arrhythmia, continuous bad thoughts, tingling in your fingers and feel dizzy. When withdrawing from 5 HTP I had horrible time. I had to withdraw slowly as I had a lot of the symptoms of SSRI withdrawal. My brain, and thoughts were so disturbing. I would be very cautious using this drug long term, and continuously. Study needs to be done on low dose naltrexone and 5 HTP. Or post-concussion and 5HTP."

1 / 10
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42 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • January 27, 2014

5-HTP (5-hydroxytryptophan) for Anxiety "It seemed to help a bit at first, but after taking it for almost a year the positive effects seemed to have disappeared completely. If you suffer from an anxiety disorder I would seriously recommend a prescription medicine. I've recently been switched to Buspar and it works wonders and is very cheap."

3 / 10
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70 Report
  • l33tDad
  • August 6, 2015

For Depression "This stuff is FANTASTIC! I've been having issues with mild depression for about a year now and really didn't want to see a psychologist to be put on some sort of antidepressant. I read about this stuff while doing a search about depression about 2 weeks ago so I decided to give it a go and I can honestly say that I'm a different person. I feel like my old self, happy, energetic and just plain ole normal. I highly recommend this!"

10 / 10
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61 Report
  • Econut
  • August 17, 2016

5-HTP (5-hydroxytryptophan) for Insomnia "I've struggled with sleep-onset insomnia for 15+ years. It started in my early forties when perimenopause hit. Tried 5-HTP recently and after 2 weeks I'm sleeping great! I take 200 mg time-release an hour before bed. Also drink milk/buttermilk before bed. And gelatin mixed with hot water and juice earlier. I only take Ambien or Ativan when I still can't get to sleep but that's unusual. Since I'm sleeping sounding again like when I was younger, my energy level is back to normal and I feel great again! I also changed my diet to low sugar/ high fiber. 5-HTP is a life saver to me!!!"

10 / 10
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53 Report
  • Inten...
  • February 19, 2017

5-HTP (5-hydroxytryptophan) for Anxiety "It's caused mixed rxn, often awake and cannot return to sleep. Foggy feelings during the day, with occasional odd sense of impending doom. Anxiety that keeps me indoors...But, when I decide to go out despite odd feelings, I find myself to be strangely aggressive. It's a seems that I'm less tolerant to other people. For example, there is a cashier who is always rude, a real eye roller, with frequent head shaking and sighs. Well, after she rolled her eyes at me for asking for a pen, she reluctantly smacked down on the counter. I tossed it at her after using it. Hmmm, this is odd behavior for me, I usually don't react to other people like that..So, I've decided to quit this 5- Htp for now. I could end up doing something that gets me on the news"

4 / 10
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50 Report
  • Lyla
  • Taken for less than 1 month
  • October 18, 2020

5-HTP (5-hydroxytryptophan) for Anxiety "I’m a 51 yo female with a long history of anxiety and depression. With menopause just around the corner there are days my anxiety is off the charts. About 6 months ago I started taking 100mg daily. I was also having moderate to severe panic, heart palpitations, sweating, and severe vomiting. I didn’t make the connection to 5HTP until I recently started taking it again. This time only 25mg. Same symptoms but milder. I cannot be 100% sure but I’m making the connection to this supplement. If you’re thinking of taking thus supplement I highly recommend talking to a holistic health practitioner first. Not to be dramatic but my episodes landed me in the ED three times last year. It was quite scary."

1 / 10
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29 Report
  • Anony...
  • Taken for less than 1 month
  • September 7, 2020

5-HTP (5-hydroxytryptophan) for Anxiety "I took 5-HTP for the first time when I was feeling terribly depressed but it only made me feel even worse. Tried it again, the same thing happened. How different reaction can be when it's applied to different people. : ("

1 / 10
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29 Report
  • gbgould
  • Taken for less than 1 month
  • September 13, 2018

5-HTP (5-hydroxytryptophan) for Anxiety "Just started and noticed the difference overnight. No more stomach churning or ulcer like pain. Was tested for ulcer- negative. Feeling relaxed and a lot smoother. A little dry mouth and I know there's something in my system but no overwhelming or harsh. Started with 50 mgs."

9 / 10
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40 Report
  • perle...
  • Taken for 1 to 6 months
  • February 2, 2019

5-HTP (5-hydroxytryptophan) for Anxiety "Combined with therapy, I can almost say for sure that 5-HTP helps me. After a really painful breakup, I was having looping suicidal thoughts (the thought of a gun going "bang" all the time) and was in a really sordid mood overall. A week or so into taking 100mg 3x daily, I felt I was going better although I didn't necessarily think 5-HTP had played a role (I'm kind of skeptical person). I thought my improving mood was 100% due to a therapy with someone who really cares. I finished my 1-month supply bottle and stopped taking. Within a day or two, my mood mysteriously took a hard hit. Just today I bought a new bottle. I'm pretty sure it'll help me again. I can't compare to big pharma meds because I never took them. I take this combined with Omega-3. I like the fact that there are 0 side effects for me. I'll continue taking 5-HTP, at least for a while. 5-HTP isn't especially cheap, but it's worth a try if your symptoms are really messing with your life."

8 / 10
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37 Report
  • Oneho...
  • January 5, 2016

5-HTP (5-hydroxytryptophan) for Anxiety "Been using timed release 200mgs for last month and used to 400mgs daily. Slight stomach and headache issues but gone after first week. Works very well but need to buy a quality product. I paired this with Niacinamide 1500-2000mgs this is all medicinal level and it's working nicely with slight mood swings. My sleep is better with higher dose and I'm not suffering major panic attacks. I'm off Seroquel for now and this is working for my seasonal depression and I am bipolar 1. I would recommend a neuropath when using this but I'm very well trained and aware of my body"

8 / 10
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52 Report
  • Chris...
  • December 6, 2017

5-HTP (5-hydroxytryptophan) for Anxiety "I've only been taking 5-htp for a few days to see if it helps my anxiety at all, and already it definitely does seem to do something! It makes me feel very warm and relaxed, like there's a deep relaxation in my chest and stomach, these effects start within an hour of dosing."

8 / 10
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42 Report
  • Anonymous
  • August 11, 2011

5-HTP (5-hydroxytryptophan) for Insomnia "It works very well with my Ambien pills which have almost stopped working but can't sleep without (sounds familiar to chronic insomniacs I guess). I fall asleep amazingly fast (faster than at any time in my life) and I sleep up to 8 hours which I had forgotten about even on Ambien! I take only 50mg in late afternoon with food because I have a sensitive stomach. I wish I had tried this before."

5 / 10
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70 Report
  • Tinodog
  • Taken for less than 1 month
  • November 24, 2019

5-HTP (5-hydroxytryptophan) for Anxiety "I recently lost my job, and going through stress. For about three weeks now I've been taking Ativan for sleep because the anxiety was keeping me up at night. I do not want to get addicted to the benzo. Tried magnesium Theronate but the side effect was tension head. Tried valerian, that just made me more anxious. I take b complex and d3 Along with prescribe by my doc. I tried 5HTP. It relaxes me but doesn’t make me feel sleepy. Do I have to up the doses to make it more effective? How many days before it started working? Any ideas? Thanks"

7 / 10
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31 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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