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Generic Name: sevoflurane (see-voe-FLOO-rane)
Brand Name: Ultane

Sevoflurane is used for:

Causing general anesthesia (loss of consciousness) before and during surgery.

Sevoflurane is an anesthetic. It works by depressing activity in the central nervous system, which causes loss of consciousness.

Do NOT use sevoflurane if:

  • you are allergic to any ingredient in sevoflurane
  • you have or have a history of severely high body temperature (malignant hyperthermia)

Contact your doctor or health care provider right away if any of these apply to you.

Before using sevoflurane:

Some medical conditions may interact with sevoflurane. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney problems or seizures

Some MEDICINES MAY INTERACT with sevoflurane. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Amiodarone, droxidopa, or labetalol because side effects, such as increased risk for low or high blood pressure and other heart complications, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if sevoflurane may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use sevoflurane:

Use sevoflurane as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Sevoflurane is usually administered by your doctor or other health care provider during surgery.
  • If you miss a dose of sevoflurane, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use sevoflurane.

Important safety information:

  • Sevoflurane will cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to sevoflurane. Using sevoflurane alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking sevoflurane, discuss with your doctor the benefits and risks of using sevoflurane during pregnancy. It is unknown if sevoflurane is excreted in breast milk. If you are or will be breast-feeding while you are using sevoflurane, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of sevoflurane:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; dizziness; drowsiness; increased cough; increased saliva; lightheadedness; nausea; shivering; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills; fast, slow, or irregular heartbeat; fever; seizures; unusual change in amount or urine; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; slow heartbeat.

Proper storage of sevoflurane:

Sevoflurane is usually handled and stored by a health care provider. If you are using sevoflurane at home, store sevoflurane as directed by your pharmacist or health care provider. Keep sevoflurane out of the reach of children and away from pets.

General information:

  • If you have any questions about sevoflurane, please talk with your doctor, pharmacist, or other health care provider.
  • Sevoflurane is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about sevoflurane. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Review Date: April 11, 2017

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.