Generic Name: Semaglutide Tablets (sem a GLOO tide)
Brand Name: Rybelsus
Medically reviewed by Drugs.com. Last updated on Nov 30, 2020.
- This medicine has been shown to cause thyroid cancer in some animals. It is not known if this happens in humans. If thyroid cancer happens, it may be deadly if not found and treated early. Call your doctor right away if you have a neck mass, trouble breathing, trouble swallowing, or have hoarseness that will not go away.
- Do not use this medicine (semaglutide tablets) if you have a health problem called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you or a family member have had thyroid cancer.
Uses of Semaglutide Tablets:
- It is used to lower blood sugar in patients with high blood sugar (diabetes).
What do I need to tell my doctor BEFORE I take Semaglutide Tablets?
- If you are allergic to this medicine (semaglutide tablets); any part of this medicine (semaglutide tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have any of these health problems: Acidic blood problem or type 1 diabetes.
- If you have ever had pancreatitis.
This is not a list of all drugs or health problems that interact with this medicine (semaglutide tablets).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (semaglutide tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Semaglutide Tablets?
- Tell all of your health care providers that you take this medicine (semaglutide tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Follow the diet and workout plan that your doctor told you about.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
- Wear disease medical alert ID (identification).
- Check your blood sugar as you have been told by your doctor.
- Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.
- It may be harder to control blood sugar during times of stress such as fever, infection, injury, or surgery. A change in physical activity, exercise, or diet may also affect blood sugar.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Talk with your doctor before you drink alcohol.
- Kidney problems have happened. Sometimes, these may need to be treated in the hospital or with dialysis.
- If you cannot drink liquids by mouth or if you have upset stomach, throwing up, or diarrhea that does not go away; you need to avoid getting dehydrated. Contact your doctor to find out what to do. Dehydration may lead to new or worse kidney problems.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Semaglutide Tablets) best taken?
Use this medicine (semaglutide tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take at least 30 minutes before the first food, drink, or drugs of the day.
- Take with plain water only. Do not take with more than 4 ounces (120 mL) of water.
- Swallow whole. Do not chew, break, or crush.
- Keep taking this medicine (semaglutide tablets) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Change in eyesight.
- Low blood sugar can happen. The chance may be raised when this medicine (semaglutide tablets) is used with other drugs for diabetes. Signs may be dizziness, headache, feeling sleepy or weak, shaking, fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do for low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices.
What are some other side effects of Semaglutide Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Constipation, diarrhea, stomach pain, upset stomach, or throwing up.
- Not hungry.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Semaglutide Tablets?
- Store in the original container at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (semaglutide tablets) is refilled. If you have any questions about this medicine (semaglutide tablets), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
- Where and how should Ozempic be injected?
- Does Rybelsus help with weight loss?
- How long does it take for Rybelsus to start working?
- What is Rybelsus used for and how does it work?
- What type of drug is Ozempic (semaglutide)?
More about semaglutide
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- 473 Reviews
- Drug class: incretin mimetics
- Patient Information
- Semaglutide (Advanced Reading)
- Semaglutide Subcutaneous (Advanced Reading)
- Semaglutide Prefilled Pens
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.