Generic Name: nitroglycerin (NYE-troe-GLIS-er-in)
Brand Name: Nitrostat
Nitroglycerin tablets are used for:
Preventing or relieving a sudden attack of angina (chest pain) caused by heart disease. It may also be used for other conditions as determined by your doctor.
Nitroglycerin tablets are a nitrate. It works by dilating (widening) blood vessels. Chest pain occurs when the heart needs more oxygen than it can get. Dilating blood vessels allows blood to flow more easily. This reduces the heart's workload and the amount of oxygen needed by the heart.
Do NOT use nitroglycerin tablets if:
- you are allergic to any ingredient in nitroglycerin tablets
- you have increased pressure in the head
- you have severe anemia
- you are also taking avanafil, riociguat, sildenafil, tadalafil, or vardenafil
Contact your doctor or health care provider right away if any of these apply to you.
Before using nitroglycerin tablets:
Some medical conditions may interact with nitroglycerin tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you drink alcoholic beverages
- if you have a history of other heart problems (eg, heart failure, an enlarged heart, a heart attack), an overactive thyroid, a stroke or other bleeding in the brain, or a recent head injury
- if you have anemia, low blood pressure, dehydration, or low blood volume
Some MEDICINES MAY INTERACT with nitroglycerin tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Avanafil, beta-blockers (eg, propranolol), calcium channel blockers (eg, diltiazem), diuretics (eg, furosemide, hydrochlorothiazide), medicines for high blood pressure, phenothiazines (eg, thioridazine), riociguat, sildenafil, tadalafil, or vardenafil because the risk of low blood pressure and dizziness when standing may be increased
- Salicylates (eg, aspirin) because they may increase the risk of nitroglycerin tablets's side effects
- Long-acting nitrates (eg, nitroglycerin patch) because they may decrease nitroglycerin tablets's effectiveness
- Ergot alkaloids (eg, dihydroergotamine, ergotamine) because the risk of their side effects may be increased by nitroglycerin tablets
- Alteplase because its effectiveness may be decreased by nitroglycerin tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if nitroglycerin tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use nitroglycerin tablets:
Use nitroglycerin tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Do NOT swallow, chew, or crush this tablet. Dissolve the tablet under the tongue or between the cheek and gum.
- To treat an angina attack, use nitroglycerin tablets at the first sign of chest pain. Sit quietly while the tablet is dissolving. The dose may be repeated every 5 minutes until you get relief or as directed by your doctor. Do not use more than 3 tablets in 15 minutes. If chest pain continues after a total of 3 tablets, seek medical attention at once, unless your doctor gives you different instructions.
- If you use nitroglycerin tablets to prevent angina caused by physical activity, use it 5 to 10 minutes before activity unless your doctor tells you otherwise.
- If you miss a dose of nitroglycerin tablets and you are still having chest pain, contact your doctor right away. Ask your health care provider any questions you may have about the proper use of nitroglycerin tablets.
Ask your health care provider any questions you may have about how to use nitroglycerin tablets.
Important safety information:
- Nitroglycerin tablets may cause dizziness, light-headedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use nitroglycerin tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Check with your doctor before you drink alcohol while you are using nitroglycerin tablets. Drinking alcohol may increase the risk of low blood pressure with nitroglycerin tablets.
- Nitroglycerin tablets may cause dizziness, light-headedness, or fainting. Sit down while taking nitroglycerin tablets. When you return to a standing position, stand slowly using caution to avoid falling caused by light-headedness or dizziness.
- Nitroglycerin tablets can cause tingling or burning when you put it under your tongue. However, lack of tingling or burning does not mean the medicine is not working.
- Contact your doctor right away if you develop slow heartbeat or new or worsening chest pain after you take nitroglycerin tablets.
- Do NOT take more than the recommended dose or use more often than prescribed without checking with your doctor.
- Keep medicine in the original glass bottle with the cap tightly closed.
- Tell your doctor or dentist that you take nitroglycerin tablets before you receive any medical or dental care, emergency care, or surgery.
- Nitroglycerin tablets may interfere with certain lab tests, including certain cholesterol tests. Be sure your doctor and lab personnel know you are using nitroglycerin tablets.
- Lab tests, including heart function, blood pressure, and blood electrolyte levels, may be performed while you take nitroglycerin tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use nitroglycerin tablets with caution in the ELDERLY; they may be more sensitive to its effects.
- Nitroglycerin tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking nitroglycerin tablets while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you are taking nitroglycerin tablets, check with your doctor. Discuss any possible risks to your baby.
When used at higher doses or more often than prescribed, nitroglycerin tablets may not work as well. This is known as TOLERANCE. Tolerance to other nitrates and nitrites may also occur. Increasing the dose is not effective in managing tolerance to nitroglycerin tablets. Talk with your doctor if nitroglycerin tablets stops working well. Do not take more than prescribed.
Possible side effects of nitroglycerin tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Burning or tingling sensation; dizziness or light-headedness; headache.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; dry mouth; fainting; fast or irregular heartbeat; flushing; heavy sweating; pale skin; restlessness; severe or persistent dizziness or headache; severe or persistent nausea or vomiting; slow or irregular heartbeat; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of nitroglycerin tablets:
Store nitroglycerin tablets in the original glass container, tightly closed, at or below 77 degrees F (25 degrees C). Protect from heat, moisture, and light. Do not store in bathroom. Keep nitroglycerin tablets out of the reach of children and away from pets.
- If you have any questions about nitroglycerin tablets, please talk with your doctor, pharmacist, or other health care provider.
- Nitroglycerin tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take nitroglycerin tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about nitroglycerin tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to nitroglycerin tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using nitroglycerin tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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